Search Results - "Engel, B."

PPARβ/δ: Linking Metabolism to Regeneration by Magadum, Ajit, Engel, Felix B

“…In contrast to the general belief that regeneration is a rare event, mainly occurring in simple organisms, the ability of regeneration is widely distributed in…”
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Cardiomyocyte proliferation in cardiac development and regeneration: a guide to methodologies and interpretations by Leone, Marina, Magadum, Ajit, Engel, Felix B

“…The newt and the zebrafish have the ability to regenerate many of their tissues and organs including the heart. Thus, a major goal in experimental medicine is…”
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Advances in heart regeneration based on cardiomyocyte proliferation and regenerative potential of binucleated cardiomyocytes and polyploidization by Leone, Marina, Engel, Felix B

“…One great achievement in medical practice is the reduction in acute mortality of myocardial infarction due to identifying risk factors, antiplatelet therapy,…”
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Novel targets and future strategies for acute cardioprotection: Position Paper of the European Society of Cardiology Working Group on Cellular Biology of the Heart by Hausenloy, Derek J, Garcia-Dorado, David, Bøtker, Hans Erik, Davidson, Sean M, Downey, James, Engel, Felix B, Jennings, Robert, Lecour, Sandrine, Leor, Jonathan, Madonna, Rosalinda, Ovize, Michel, Perrino, Cinzia, Prunier, Fabrice, Schulz, Rainer, Sluijter, Joost P G, Van Laake, Linda W, Vinten-Johansen, Jakob, Yellon, Derek M, Ytrehus, Kirsti, Heusch, Gerd, Ferdinandy, Péter

“…Ischaemic heart disease and the heart failure that often results, remain the leading causes of death and disability in Europe and worldwide. As such, in order…”
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Silk proteins for biomedical applications: Bioengineering perspectives by Kundu, Banani, Kurland, Nicholas E., Bano, Subia, Patra, Chinmoy, Engel, Felix B., Yadavalli, Vamsi K., Kundu, Subhas C.

“…Biomaterials of either natural or synthetic origin are used to fabricate implantable devices, as carriers for bioactive molecules or as substrates to…”
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Phase-locking in double-point-contact spin-transfer devices by Mancoff, F. B, Rizzo, N. D, Engel, B. N, Tehrani, S

“…Spin-transfer in nanometre-scale magnetic devices results from the torque on a ferromagnet owing to its interaction with a spin-polarized current and the…”
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A review of preanalytical factors affecting molecular, protein, and morphological analysis of formalin-fixed, paraffin-embedded (FFPE) tissue: how well do you know your FFPE specimen? by Bass, B Paige, Engel, Kelly B, Greytak, Sarah R, Moore, Helen M

“…Formalin fixation and paraffin embedding is a timeless, cost-efficient, and widely adopted method of preserving human tissue biospecimens that has resulted in…”
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Effects of preanalytical variables on the detection of proteins by immunohistochemistry in formalin-fixed, paraffin-embedded tissue by Engel, Kelly B, Moore, Helen M

“…While formalin fixation and paraffin embedding has become a universal mechanism of tissue preservation and a gold standard for immunohistochemistry, fixation…”
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Treat-to-target (T2T) recommendations for gout by Kiltz, U, Smolen, J, Bardin, T, Cohen Solal, A, Dalbeth, N, Doherty, M, Engel, B, Flader, C, Kay, J, Matsuoka, M, Perez-Ruiz, F, da Rocha Castelar-Pinheiro, G, Saag, K, So, A, Vazquez Mellado, J, Weisman, M, Westhoff, T H, Yamanaka, H, Braun, J

“…The treat-to-target (T2T) concept has been applied successfully in several inflammatory rheumatic diseases. Gout is a chronic disease with a high burden of…”
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Towards quantification of the national water footprint in rice production of China: A first assessment from the perspectives of single-double rice by Zheng, Jiazhong, Wang, Weiguang, Liu, Guoshuai, Ding, Yimin, Cao, Xinchun, Chen, Dan, Engel, B.A.

“…Rice is one of the most important crops in China, contributing to approximately 28% of total cereal yield. Despite substantial production, given that rice is a…”
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Position Paper of the European Society of Cardiology Working Group Cellular Biology of the Heart: cell-based therapies for myocardial repair and regeneration in ischemic heart disease and heart failure by Madonna, Rosalinda, Van Laake, Linda W, Davidson, Sean M, Engel, Felix B, Hausenloy, Derek J, Lecour, Sandrine, Leor, Jonathan, Perrino, Cinzia, Schulz, Rainer, Ytrehus, Kirsti, Landmesser, Ulf, Mummery, Christine L, Janssens, Stefan, Willerson, James, Eschenhagen, Thomas, Ferdinandy, Péter, Sluijter, Joost P G

“…Despite improvements in modern cardiovascular therapy, the morbidity and mortality of ischaemic heart disease (IHD) and heart failure (HF) remain significant…”
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mTORC1 Controls Phase Separation and the Biophysical Properties of the Cytoplasm by Tuning Crowding by Delarue, M., Brittingham, G.P., Pfeffer, S., Surovtsev, I.V., Pinglay, S., Kennedy, K.J., Schaffer, M., Gutierrez, J.I., Sang, D., Poterewicz, G., Chung, J.K., Plitzko, J.M., Groves, J.T., Jacobs-Wagner, C., Engel, B.D., Holt, L.J.

“…Macromolecular crowding has a profound impact on reaction rates and the physical properties of the cell interior, but the mechanisms that regulate crowding are…”
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International Union of Basic and Clinical Pharmacology. XCIV. Adhesion G protein-coupled receptors by Hamann, Jörg, Aust, Gabriela, Araç, Demet, Engel, Felix B, Formstone, Caroline, Fredriksson, Robert, Hall, Randy A, Harty, Breanne L, Kirchhoff, Christiane, Knapp, Barbara, Krishnan, Arunkumar, Liebscher, Ines, Lin, Hsi-Hsien, Martinelli, David C, Monk, Kelly R, Peeters, Miriam C, Piao, Xianhua, Prömel, Simone, Schöneberg, Torsten, Schwartz, Thue W, Singer, Kathleen, Stacey, Martin, Ushkaryov, Yuri A, Vallon, Mario, Wolfrum, Uwe, Wright, Mathew W, Xu, Lei, Langenhan, Tobias, Schiöth, Helgi B

“…The Adhesion family forms a large branch of the pharmacologically important superfamily of G protein-coupled receptors (GPCRs). As Adhesion GPCRs increasingly…”
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Spatially Resolved Genome-wide Transcriptional Profiling Identifies BMP Signaling as Essential Regulator of Zebrafish Cardiomyocyte Regeneration by Wu, Chi-Chung, Kruse, Fabian, Vasudevarao, Mohankrishna Dalvoy, Junker, Jan Philipp, Zebrowski, David C., Fischer, Kristin, Noël, Emily S., Grün, Dominic, Berezikov, Eugene, Engel, Felix B., van Oudenaarden, Alexander, Weidinger, Gilbert, Bakkers, Jeroen

“…In contrast to mammals, zebrafish regenerate heart injuries via proliferation of cardiomyocytes located near the wound border. To identify regulators…”
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ESC working group cellular biology of the heart: position paper: improving the preclinical assessment of novel cardioprotective therapies by Lecour, Sandrine, Bøtker, Hans E, Condorelli, Gianluigi, Davidson, Sean M, Garcia-Dorado, David, Engel, Felix B, Ferdinandy, Peter, Heusch, Gerd, Madonna, Rosalinda, Ovize, Michel, Ruiz-Meana, Marisol, Schulz, Rainer, Sluijter, Joost P G, Van Laake, Linda W, Yellon, Derek M, Hausenloy, Derek J

“…Ischaemic heart disease (IHD) remains the leading cause of death and disability worldwide. As a result, novel therapies are still needed to protect the heart…”
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Gpr126 functions in Schwann cells to control differentiation and myelination via G-protein activation by Mogha, Amit, Benesh, Andrew E, Patra, Chinmoy, Engel, Felix B, Schöneberg, Torsten, Liebscher, Ines, Monk, Kelly R

“…The myelin sheath surrounding axons ensures that nerve impulses travel quickly and efficiently, allowing for the proper function of the vertebrate nervous…”
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Effects of transport age and calf and maternal characteristics on health and performance of veal calves by Marcato, F., van den Brand, H., Kemp, B., Engel, B., Schnabel, S.K., Hoorweg, F.A., Wolthuis-Fillerup, M., van Reenen, K.

“…The objective of this study was to investigate effects of calf transport age (14 vs. 28 d) and calf (e.g., sex and breed) and dam characteristics (e.g., parity…”
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Towards regenerating the mammalian heart: challenges in evaluating experimentally induced adult mammalian cardiomyocyte proliferation by Zebrowski, David C, Becker, Robert, Engel, Felix B

“…In recent years, there has been a dramatic increase in research aimed at regenerating the mammalian heart by promoting endogenous cardiomyocyte proliferation…”
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Application of water footprint combined with a unified virtual crop pattern to evaluate crop water productivity in grain production in China by Wang, Y.B., Wu, P.T., Engel, B.A., Sun, S.K.

“…Water shortages are detrimental to China's grain production while food production consumes a great deal of water causing water crises and ecological impacts…”
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Differential association of STK11 and TP53 with KRAS mutation-associated gene expression, proliferation and immune surveillance in lung adenocarcinoma by Schabath, M B, Welsh, E A, Fulp, W J, Chen, L, Teer, J K, Thompson, Z J, Engel, B E, Xie, M, Berglund, A E, Creelan, B C, Antonia, S J, Gray, J E, Eschrich, S A, Chen, D-T, Cress, W D, Haura, E B, Beg, A A

“…While mutations in the KRAS oncogene are among the most prevalent in human cancer, there are few successful treatments to target these tumors. It is also…”
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