Search Results - "Eng, Huiyan"
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PI3K/AKT/mTOR signaling transduction pathway and targeted therapies in cancer
Published in Molecular cancer (18-08-2023)“…The PI3K/AKT/mTOR (PAM) signaling pathway is a highly conserved signal transduction network in eukaryotic cells that promotes cell survival, cell growth, and…”
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Journal Article -
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2,3,5,6-Tetramethylpyrazine Targets Epithelial-Mesenchymal Transition by Abrogating Manganese Superoxide Dismutase Expression and TGFβ-Driven Signaling Cascades in Colon Cancer Cells
Published in Biomolecules (Basel, Switzerland) (25-06-2022)“…Epithelial-mesenchymal transition (EMT) is a crucial process in which the polarized epithelial cells acquire the properties of mesenchymal cells and gain…”
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Journal Article -
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Delineating the role of nuclear receptors in colorectal cancer, a focused review
Published in Discover. Oncology (19-02-2024)“…Colorectal cancer (CRC) stands as one of the most prevalent form of cancer globally, causing a significant number of deaths, surpassing 0.9 million in the year…”
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Journal Article -
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Detection of the 113p53 protein isoform: A p53-induced protein that feeds back on the p53 pathway to modulate the p53 response in zebrafish
Published in Cell cycle (Georgetown, Tex.) (15-05-2010)“…Isoforms of p53 have been described in both zebrafish and human systems based on sensitive analysis of RNA using PCR-based methods. Despite consistent evidence…”
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Journal Article -
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Use of antibody engineering to improve the properties of antibodies as reagents
Published 01-01-2015“…The aim of this project is to generate a best-in-class antibody for use against mouse p53 with particular focus on the immunohistochemical (“IHC”) staining of…”
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Dissertation