Search Results - "Eng, Cathy"

The Evolving Role of Monoclonal Antibodies in Colorectal Cancer: Early Presumptions and Impact on Clinical Trial Development by Eng, Cathy

“…Targeted biologic agents have an established role in treating metastatic colorectal cancer (mCRC). Bevacizumab, a recombinant monoclonal antibody against the…”
Get full text

A Practical Approach to the Management of Cancer Patients During the Novel Coronavirus Disease 2019 (COVID‐19) Pandemic: An International Collaborative Group by Al‐Shamsi, Humaid O., Alhazzani, Waleed, Alhuraiji, Ahmad, Coomes, Eric A., Chemaly, Roy F., Almuhanna, Meshari, Wolff, Robert A., Ibrahim, Nuhad K., Chua, Melvin L.K., Hotte, Sebastien J., Meyers, Brandon M., Elfiki, Tarek, Curigliano, Giuseppe, Eng, Cathy, Grothey, Axel, Xie, Conghua

“…The outbreak of coronavirus disease 2019 (COVID‐19) has rapidly spread globally since being identified as a public health emergency of major international…”
Get full text

Treatment of Metastatic Colorectal Cancer: ASCO Guideline by Morris, Van K, Kennedy, Erin B, Baxter, Nancy N, Benson, 3rd, Al B, Cercek, Andrea, Cho, May, Ciombor, Kristen K, Cremolini, Chiara, Davis, Anjee, Deming, Dustin A, Fakih, Marwan G, Gholami, Sepideh, Hong, Theodore S, Jaiyesimi, Ishmael, Klute, Kelsey, Lieu, Christopher, Sanoff, Hanna, Strickler, John H, White, Sarah, Willis, Jason A, Eng, Cathy

“…To develop recommendations for treatment of patients with metastatic colorectal cancer (mCRC). ASCO convened an Expert Panel to conduct a systematic review of…”
Get full text

Antiemetics: American Society of Clinical Oncology Clinical Practice Guideline Update by Hesketh, Paul J, Kris, Mark G, Basch, Ethan, Bohlke, Kari, Barbour, Sally Y, Clark-Snow, Rebecca Anne, Danso, Michael A, Dennis, Kristopher, Dupuis, L Lee, Dusetzina, Stacie B, Eng, Cathy, Feyer, Petra C, Jordan, Karin, Noonan, Kimberly, Sparacio, Dee, Somerfield, Mark R, Lyman, Gary H

“…Purpose To update the ASCO guideline for antiemetics in oncology. Methods ASCO convened an Expert Panel and conducted a systematic review of the medical…”
Get full text

Antiemetics: ASCO Guideline Update by Hesketh, Paul J, Kris, Mark G, Basch, Ethan, Bohlke, Kari, Barbour, Sally Y, Clark-Snow, Rebecca Anne, Danso, Michael A, Dennis, Kristopher, Dupuis, L Lee, Dusetzina, Stacie B, Eng, Cathy, Feyer, Petra C, Jordan, Karin, Noonan, Kimberly, Sparacio, Dee, Lyman, Gary H

“…To update the guideline to include new anticancer agents, antiemetics, and antiemetic regimens and to provide recommendations on the use of dexamethasone as a…”
Get full text

Nivolumab for previously treated unresectable metastatic anal cancer (NCI9673): a multicentre, single-arm, phase 2 study by Morris, Van K, MD, Salem, Mohamed E, MD, Nimeiri, Halla, MD, Iqbal, Syma, MD, Singh, Preet, MD, Ciombor, Kristen, MD, Polite, Blase, MD, Deming, Dustin, MD, Chan, Emily, MD, Wade, James L, MD, Xiao, Lianchun, MS, Bekaii-Saab, Tanios, Prof, Vence, Luis, PhD, Blando, Jorge, DVM, Mahvash, Armeen, MD, Foo, Wai Chin, MD, Ohaji, Chimela, MD, Pasia, Manolo, BSN, Bland, Gail, BS, Ohinata, Aki, PAC, Rogers, Jane, PharmD, Mehdizadeh, Amir, MA, Banks, Kimberly, MS, Lanman, Richard, MD, Wolff, Robert A, Prof, Streicher, Howard, MD, Allison, James, Prof, Sharma, Padmanee, Prof, Eng, Cathy, Prof

“…Summary Background Squamous cell carcinoma of the anal canal (SCCA) is a rare malignancy associated with infection by human papillomavirus (HPV). No consensus…”
Get full text

Comprehensive Genomic Landscapes in Early and Later Onset Colorectal Cancer by Lieu, Christopher H, Golemis, Erica A, Serebriiskii, Ilya G, Newberg, Justin, Hemmerich, Amanda, Connelly, Caitlin, Messersmith, Wells A, Eng, Cathy, Eckhardt, S Gail, Frampton, Garrett, Cooke, Matthew, Meyer, Joshua E

“…The incidence rates of colorectal cancers are increasing in young adults. The objective of this study was to investigate genomic differences between tumor…”
Get full text

Classifying Colorectal Cancer by Tumor Location Rather than Sidedness Highlights a Continuum in Mutation Profiles and Consensus Molecular Subtypes by Loree, Jonathan M, Pereira, Allan A L, Lam, Michael, Willauer, Alexandra N, Raghav, Kanwal, Dasari, Arvind, Morris, Van K, Advani, Shailesh, Menter, David G, Eng, Cathy, Shaw, Kenna, Broaddus, Russell, Routbort, Mark J, Liu, Yusha, Morris, Jeffrey S, Luthra, Rajyalakshmi, Meric-Bernstam, Funda, Overman, Michael J, Maru, Dipen, Kopetz, Scott

“…Colorectal cancers are classified as right/left-sided based on whether they occur before/after the splenic flexure, with established differences in molecular…”
Get full text

Improved Survival in Metastatic Colorectal Cancer Is Associated With Adoption of Hepatic Resection and Improved Chemotherapy by KOPETZ, Scott, CHANG, George J, OVERMAN, Michael J, ENG, Cathy, SARGENT, Daniel J, LARSON, David W, GROTHEY, Axel, VAUTHEY, Jean-Nicolas, NAGORNEY, David M, MCWILLIAMS, Robert R

“…Fluorouracil/leucovorin as the sole therapy for metastatic colorectal cancer (CRC) provides an overall survival of 8 to 12 months. With an increase in surgical…”
Get full text

Neoadjuvant Treatment Response As an Early Response Indicator for Patients With Rectal Cancer by Park, In Ja, You, Y Nancy, Agarwal, Atin, Skibber, John M, Rodriguez-Bigas, Miguel A, Eng, Cathy, Feig, Barry W, Das, Prajnan, Krishnan, Sunil, Crane, Christopher H, Hu, Chung-Yuan, Chang, George J

“…Neoadjuvant chemoradiotherapy for rectal cancer is associated with improved local control and may result in complete tumor response. Associations between tumor…”
Get full text

High Survival Rate After Two-Stage Resection of Advanced Colorectal Liver Metastases: Response-Based Selection and Complete Resection Define Outcome by BROUQUET, Antoine, ABDALLA, Eddie K, VAUTHEY, Jean-Nicolas, KOPETZ, Scott, GARRETT, Christopher R, OVERMAN, Michael J, ENG, Cathy, ANDREOU, Andreas, LOYER, Evelyne M, MADOFF, David C, CURLEY, Steven A

“…Prolonged survival after two-stage resection (TSR) of advanced colorectal liver metastases (CLM) may be the result of selection of best responders to…”
Get full text

Randomized controlled trial of neurofeedback on chemotherapy‐induced peripheral neuropathy: A pilot study by Prinsloo, Sarah, Novy, Diane, Driver, Larry, Lyle, Randall, Ramondetta, Lois, Eng, Cathy, McQuade, Jennifer, Lopez, Gabriel, Cohen, Lorenzo

“…BACKGROUND Chemotherapy‐induced peripheral neuropathy (CIPN) is a significant problem for cancer patients, and there are limited treatment options for this…”
Get full text

Trends in colorectal cancer incidence by anatomic site and disease stage in the United States from 1976 to 2005 by Cheng, Lee, Eng, Cathy, Nieman, Linda Z, Kapadia, Asha S, Du, Xianglin L

“…The objectives of the current study were to examine the trends in incidence rates of subsite-specific colorectal cancer at all stages in a large US population…”
Get full text

Impact of Recurrence and Salvage Surgery on Survival After Multidisciplinary Treatment of Rectal Cancer by Ikoma, Naruhiko, You, Y Nancy, Bednarski, Brian K, Rodriguez-Bigas, Miguel A, Eng, Cathy, Das, Prajnan, Kopetz, Scott, Messick, Craig, Skibber, John M, Chang, George J

“…Purpose After preoperative chemoradiotherapy followed by total mesorectal excision for locally advanced rectal cancer, patients who experience local or…”
Get full text

Phase II Trial of Infusional Fluorouracil, Irinotecan, and Bevacizumab for Metastatic Colorectal Cancer: Efficacy and Circulating Angiogenic Biomarkers Associated With Therapeutic Resistance by KOPETZ, Scott, HOFF, Paulo M, LIEU, Christopher, SHAOYU YAN, TRAN, Hai T, ELLIS, Lee M, ABBRUZZESE, James L, HEYMACH, John V, MORRIS, Jeffrey S, WOLFF, Robert A, ENG, Cathy, GLOVER, Katrina Y, ADININ, Rosie, OVERMAN, Michael J, VALERO, Vincete, SIJIN WEN

“…We investigated the efficacy of fluorouracil (FU), leucovorin, irinotecan, and bevacizumab (FOLFIRI + B) in a phase II trial in patients previously untreated…”
Get full text

Survival outcomes used to generate version 9 American Joint Committee on Cancer staging system for anal cancer by Janczewski, Lauren M., Faski, Joseph, Nelson, Heidi, Gollub, Marc J., Eng, Cathy, Brierley, James D., Palefsky, Joel M., Goldberg, Richard M., Washington, M. Kay, Asare, Elliot A., Goodman, Karyn A.

“…The American Joint Committee on Cancer (AJCC) staging system for all cancer sites, including anal cancer, is the standard for cancer staging in the United…”
Get full text

Comprehensive Genomic Profiling of Metastatic Squamous Cell Carcinoma of the Anal Canal by Morris, Van, Rao, Xiayu, Pickering, Curtis, Foo, Wai Chin, Rashid, Asif, Eterovic, Karina, Kim, Taebeom, Chen, Ken, Wang, Jing, Shaw, Kenna, Eng, Cathy

“…Squamous cell carcinoma of the anal canal (SCCA) is a rare gastrointestinal malignancy with an increasing annual incidence globally. The majority of cases are…”
Get full text

Low-grade Appendiceal Mucinous Neoplasm of Uncertain Malignant Potential (LAMN-UMP): Prognostic Factors and Implications for Treatment and Follow-up by Fournier, Keith, Rafeeq, Safia, Taggart, Melissa, Kanaby, Paul, Ning, Jing, Chen, Hsiang-Chun, Overman, Michael, Raghav, Kanwal, Eng, Cathy, Mansfield, Paul, Royal, Richard

“…Background Low-grade appendiceal mucinous neoplasm of uncertain malignant potential are poorly understood lesions characterized by extraluminal mucin or…”
Get full text

Global and targeted serum metabolic profiling of colorectal cancer progression by Long, Yin, Sanchez‐Espiridion, Beatriz, Lin, Moubin, White, Lindsey, Mishra, Lopa, Raju, Gottumakkala S., Kopetz, Scott, Eng, Cathy, Hildebrandt, Michelle A. T., Chang, David W., Ye, Yuanqing, Liang, Dong, Wu, Xifeng

“…BACKGROUND Patients with colorectal adenoma polyps (PLPs) are at higher risk for developing colorectal cancer (CRC). However, the development of improved and…”
Get full text

Phase II Trial of Neoadjuvant Bevacizumab, Capecitabine, and Radiotherapy for Locally Advanced Rectal Cancer by Crane, Christopher H., M.D, Eng, Cathy, M.D, Feig, Barry W., M.D, Das, Prajnan, M.D, Skibber, John M., M.D, Chang, George J., M.D, Wolff, Robert A., M.D, Krishnan, Sunil, M.D, Hamilton, Stanley, M.D, Janjan, Nora A., M.D, Maru, Dipen M., M.D, Ellis, Lee M., M.D, Rodriguez-Bigas, Miguel A., M.D

“…Purpose We designed this Phase II trial to assess the efficacy and safety of the addition of bevacizumab to concurrent neoadjuvant capecitabine-based…”
Get full text