Search Results - "Endo, Hitoshi"
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Butyrate-producing probiotics reduce nonalcoholic fatty liver disease progression in rats: new insight into the probiotics for the gut-liver axis
Published in PloS one (16-05-2013)“…Nonalcoholic fatty liver disease (NAFLD) includes simple steatosis, nonalcoholic steatohepatitis (NASH), fibrosis, cirrhosis, and hepatocellular carcinoma. The…”
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Biomarker combination predicting imminent relapse after discontinuation of biological drugs in patients with rheumatoid arthritis in remission
Published in PloS one (21-03-2024)“…Compared to conventional disease-modifying antirheumatic drugs (DMARDs), biological DMARDs demonstrate superior efficacy but come with higher costs and…”
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3
Glucose starvation induces LKB1-AMPK-mediated MMP-9 expression in cancer cells
Published in Scientific reports (04-07-2018)“…Cancer cells utilise the glycolytic pathway to support their rapid growth and proliferation. Since cells in most solid tumours are subjected to severe…”
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A novel multi-biomarker combination predicting relapse from long-term remission after discontinuation of biological drugs in rheumatoid arthritis
Published in Scientific reports (21-10-2021)“…Biological disease modifying anti-rheumatic drugs (bDMARDs) show dramatic treatment efficacy in rheumatoid arthritis (RA). Long-term use of bDMARDs, however,…”
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5
NAC-MYB-based transcriptional regulation of secondary cell wall biosynthesis in land plants
Published in Frontiers in plant science (05-05-2015)“…Plant cells biosynthesize primary cell walls (PCW) in all cells and produce secondary cell walls (SCWs) in specific cell types that conduct water and/or…”
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Serum level of IFNβ distinguishes early from late relapses after biologics withdrawal in rheumatoid arthritis
Published in Scientific reports (03-10-2022)“…Since the advent of biological disease modifying anti-rheumatic drugs (bDMARDs) in the treatment of rheumatoid arthritis (RA), most RA patients receiving such…”
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7
Metabolic reprogramming sustains cancer cell survival following extracellular matrix detachment
Published in Redox biology (01-09-2020)“…Epithelial cells require attachment to a support, such as the extracellular matrix, for survival. During cancer progression and metastasis, cancerous…”
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Transcription Factors VND1-VND3 Contribute to Cotyledon Xylem Vessel Formation
Published in Plant physiology (Bethesda) (01-01-2018)“…Arabidopsis (Arabidopsis thaliana) VASCULAR-RELATED NAC-DOMAIN1 (VND1) to VND7 encode a group of NAC domain transcription factors that function as master…”
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9
Current status of the neutron resonance spin echo spectrometer on BL06 “VIN ROSE” at MLF, J-PARC
Published in Physica. B, Condensed matter (01-07-2019)“…Neutron spin echo technique is essential for high resolution inelastic and quasi-elastic neutron scattering experiments. We have developed a neutron resonance…”
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10
Multiple classes of transcription factors regulate the expression of VASCULAR-RELATED NAC-DOMAIN7, a master switch of xylem vessel differentiation
Published in Plant and cell physiology (01-02-2015)“…The secondary cell walls of xylem cells, including vessel elements, provide mechanical strength and contribute to the conduction of water and minerals…”
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Mitochondrial Functions and Estrogen Receptor-dependent Nuclear Translocation of Pleiotropic Human Prohibitin 2
Published in The Journal of biological chemistry (24-11-2006)“…Proteins with multiple cellular functions provide biological diversity to eukaryotic cells. In the current studies, we identified the mitochondrial functions…”
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12
Branched-chain amino acids govern the high learning ability phenotype in Tokai high avoider (THA) rats
Published in Scientific reports (29-11-2021)“…To fully understand the mechanisms governing learning and memory, animal models with minor interindividual variability and higher cognitive function are…”
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13
Interaction of human mitochondrial transcription factor A in mitochondria: its involvement in the dynamics of mitochondrial DNA nucleoids
Published in Genes to cells : devoted to molecular & cellular mechanisms (01-12-2015)“…Mitochondrial transcription factor A (TFAM) is a key regulator of mitochondrial DNA (mtDNA). TFAM interacts with itself and forms dimers; however, the precise…”
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14
Tip60/KAT5 Histone Acetyltransferase Is Required for Maintenance and Neurogenesis of Embryonic Neural Stem Cells
Published in International journal of molecular sciences (20-01-2023)“…Epigenetic regulation via epigenetic factors in collaboration with tissue-specific transcription factors is curtail for establishing functional organ systems…”
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A nationwide cross-sectional survey on hepatitis B and C screening among workers in Japan
Published in Scientific reports (10-07-2020)“…In Japan, there is no publicly funded screening for hepatitis B virus (HBV) and hepatitis C virus (HCV) infections (using HBs antigen and HCV antibody,…”
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16
Human prohibitin 1 maintains the organization and stability of the mitochondrial nucleoids
Published in Experimental cell research (10-03-2008)“…Mitochondrial prohibitin (PHB) proteins have diverse functions, such as the regulation of apoptosis and the maintenance of mitochondrial morphology. In this…”
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Evaluation of Erastin as a Therapeutic Agent Under Hypoxic Conditions in Pancreatic Cancer Cells
Published in Anticancer research (01-12-2021)“…Background/Aim: In pancreatic cancer tissues, hypoxic areas exist due to poor blood flow. Attenuation of the pharmacological efficacy of existing anticancer…”
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18
Loss of mitochondrial transcription factor A in neural stem cells leads to immature brain development and triggers the activation of the integral stress response in vivo
Published in PloS one (28-07-2021)“…Mitochondrial dysfunction is significantly associated with neurological deficits and age-related neurological diseases. While mitochondria are dynamically…”
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Superovulation with an anti-inhibin monoclonal antibody improves the reproductive performance of rat strains by increasing the pregnancy rate and the litter size
Published in Scientific reports (26-04-2024)“…Rats are multiparous rodents that have been used extensively in research; however, the low reproductive performance of some rat strains hampers the broader use…”
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Gelation Mechanism of Poly(N-isopropylacrylamide)−Clay Nanocomposite Gels
Published in Macromolecules (12-06-2007)“…The gelation mechanism of poly(N-isopropylacrylamide)−clay nanocomposite gels (NC gel) was investigated by dynamic light scattering (DLS) and contrast…”
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