Search Results - "Endapally, Shreya"
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Molecular Discrimination between Two Conformations of Sphingomyelin in Plasma Membranes
Published in Cell (21-02-2019)“…Sphingomyelin and cholesterol are essential lipids that are enriched in plasma membranes of animal cells, where they interact to regulate membrane properties…”
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Ostreolysin A and anthrolysin O use different mechanisms to control movement of cholesterol from the plasma membrane to the endoplasmic reticulum
Published in The Journal of biological chemistry (15-11-2019)“…Recent studies using two cholesterol-binding bacterial toxin proteins, perfringolysin O (PFO) and domain 4 of anthrolysin O (ALOD4), have shown that…”
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Oxysterols provide innate immunity to bacterial infection by mobilizing cell surface accessible cholesterol
Published in Nature microbiology (01-07-2020)“…Cholesterol 25-hydroxylase ( CH25H ) is an interferon-stimulated gene that converts cholesterol to the oxysterol 25-hydroxycholesterol (25HC). Circulating 25HC…”
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OlyA – A Tool to Study Sphingomyelin‐Cholesterol Interactions in Plasma Membranes
Published in The FASEB journal (01-04-2017)“…Abstract only Sphingomyelin (SM) and cholesterol are lipids that are critical for the function of animal cells. Interplay between these two lipids is important…”
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Sphingomyelin‐Cholesterol Complexes In Plasma Membranes
Published in The FASEB journal (01-04-2018)“…Sphingomyelin(SM) and cholesterol are lipids that are critical for the function of animal cells. Interplay between these two lipids is important for…”
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Sphingomyelin-Cholesterol Complexes in Plasma Membranes
Published in Biophysical journal (02-02-2018)Get full text
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A cholesterol-binding bacterial toxin provides a strategy for identifying a specific Scap inhibitor that blocks lipid synthesis in animal cells
Published in Proceedings of the National Academy of Sciences - PNAS (13-02-2024)“…Lipid synthesis is regulated by the actions of Scap, a polytopic membrane protein that binds cholesterol in membranes of the endoplasmic reticulum (ER). When…”
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