Search Results - "En Siew, Bei"

MiR-138 is a potent regulator of the heterogenous MYC transcript population in cancers by Desi, Ng, Teh, Velda, Tong, Qing Yun, Lim, Chun You, Tabatabaeian, Hossein, Chew, Xiao Hong, Sanchez-Mejias, Avencia, Chan, Jia Jia, Zhang, Bin, Pitcheshwar, Priyankaa, Siew, Bei-En, Wang, Shi, Lee, Kuok-Chung, Chong, Choon-Seng, Cheong, Wai-Kit, Lieske, Bettina, Tan, Ian Jse-Wei, Tan, Ker-Kan, Tay, Yvonne

“…3′UTR shortening in cancer has been shown to activate oncogenes, partly through the loss of microRNA-mediated repression. This suggests that many reported…”
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Global analysis of RNA-binding proteins identifies a positive feedback loop between LARP1 and MYC that promotes tumorigenesis by Desi, Ng, Tong, Qing Yun, Teh, Velda, Chan, Jia Jia, Zhang, Bin, Tabatabaeian, Hossein, Tan, Hui Qing, Kapeli, Katannya, Jin, Wenhao, Lim, Chun You, Kwok, Zhi Hao, Tan, Hwee Tong, Wang, Shi, Siew, Bei-En, Lee, Kuok-Chung, Chong, Choon-Seng, Tan, Ker-Kan, Yang, Henry, Kappei, Dennis, Yeo, Gene W., Chung, Maxey Ching Ming, Tay, Yvonne

“…In addition to genomic alterations, aberrant changes in post-transcriptional regulation can modify gene function and drive cancer development. RNA-binding…”
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Preoperative Quality of Life and Mental Health Can Predict Postoperative Outcomes and Quality of Life after Colorectal Cancer Surgery by Law, Jia-Hao, Lau, Jerrald, Pang, Ning-Qi, Khoo, Athena Ming-Gui, Cheong, Wai-Kit, Lieske, Bettina, Chong, Choon-Seng, Lee, Kuok-Chung, Tan, Ian Jse-Wei, Siew, Bei-En, Lim, Yi-Xuan, Ang, Chermaine, Choe, Lina, Koh, Wei-Ling, Ng, Alyssa, Tan, Ker-Kan

“…: It remains unclear which domains of preoperative health-related quality of life (HRQOL) and mental health are predictive of postoperative clinical and…”
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Circular RNA as a source of neoantigens for cancer vaccines by Ren, Yi, Manoharan, Thamizhanban, Liu, Beijia, Cheng, Cyrus Zai Ming, En Siew, Bei, Cheong, Wai-Kit, Lee, Kai Yin, Tan, Ian Jse-Wei, Lieske, Bettina, Tan, Ker-Kan, Chia, Gloryn

“…BackgroundThe effectiveness of somatic neoantigen-based immunotherapy is often hindered by the limited number of mutations in tumors with low to moderate…”
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A functional personalised oncology approach against metastatic colorectal cancer in matched patient derived organoids by Thng, Dexter Kai Hao, Hooi, Lissa, Siew, Bei En, Lee, Kai-Yin, Tan, Ian Jse-Wei, Lieske, Bettina, Lin, Norman Sihan, Kow, Alfred Wei Chieh, Wang, Shi, Rashid, Masturah Bte Mohd Abdul, Ang, Chermaine, Koh, Jasmin Jia Min, Toh, Tan Boon, Tan, Ker-Kan, Chow, Edward Kai-Hua

“…Globally, colorectal cancer (CRC) is the third most frequently occurring cancer. Progression on to an advanced metastatic malignancy (metCRC) is often…”
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The effect of chicken extract on ERK/CREB signaling is ApoE isoform-dependent by Yong, Shan-May, Ong, Qi-Rui, Siew, Bei-En, Wong, Boon-Seng

“…It is unclear how the nutritional supplement chicken extract (CE) enhances cognition. Human apolipoprotein E (ApoE) can regulate cognition and this…”
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Pan-cancer pervasive upregulation of 3′ UTR splicing drives tumourigenesis by Chan, Jia Jia, Zhang, Bin, Chew, Xiao Hong, Salhi, Adil, Kwok, Zhi Hao, Lim, Chun You, Desi, Ng, Subramaniam, Nagavidya, Siemens, Angela, Kinanti, Tyas, Ong, Shane, Sanchez-Mejias, Avencia, Ly, Phuong Thao, An, Omer, Sundar, Raghav, Fan, Xiaonan, Wang, Shi, Siew, Bei En, Lee, Kuok Chung, Chong, Choon Seng, Lieske, Bettina, Cheong, Wai-Kit, Goh, Yufen, Fam, Wee Nih, Ooi, Melissa G., Koh, Bryan T. H., Iyer, Shridhar Ganpathi, Ling, Wen Huan, Chen, Jianbin, Yoong, Boon-Koon, Chanwat, Rawisak, Bonney, Glenn Kunnath, Goh, Brian K. P., Zhai, Weiwei, Fullwood, Melissa J., Wang, Wilson, Tan, Ker-Kan, Chng, Wee Joo, Dan, Yock Young, Pitt, Jason J., Roca, Xavier, Guccione, Ernesto, Vardy, Leah A., Chen, Leilei, Gao, Xin, Chow, Pierce K. H., Yang, Henry, Tay, Yvonne

“…Most mammalian genes generate messenger RNAs with variable untranslated regions (UTRs) that are important post-transcriptional regulators. In cancer,…”
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An isoform-resolution transcriptomic atlas of colorectal cancer from long-read single-cell sequencing by Li, Zhongxiao, Zhang, Bin, Chan, Jia Jia, Tabatabaeian, Hossein, Tong, Qing Yun, Chew, Xiao Hong, Fan, Xiaonan, Driguez, Patrick, Chan, Charlene, Cheong, Faith, Wang, Shi, Siew, Bei En, Tan, Ian Jse-Wei, Lee, Kai-Yin, Lieske, Bettina, Cheong, Wai-Kit, Kappei, Dennis, Tan, Ker-Kan, Gao, Xin, Tay, Yvonne

“…Colorectal cancer (CRC) ranks as the second leading cause of cancer deaths globally. In recent years, short-read single-cell RNA sequencing (scRNA-seq) has…”
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Abstract 4356: An isoform-resolution transcriptomic atlas of colorectal cancer from long-read single-cell sequencing by Li, Zhongxiao, Zhang, Bin, Chan, Jia Jia, Tabatabaeian, Hossein, Tong, Qing Yun, Chew, Xiao Hong, Fan, Xiaonan, Chan, Charlene, Driguez, Patrick, Cheong, Faith, Wang, Shi, Siew, Bei En, Tan, Ian Jse-Wei, Lee, Kai-Yin, Lieske, Bettina, Cheong, Wai-Kit, Kappei, Dennis, Tan, Ker-Kan, Gao, Xin, Tay, Yvonne

“…Abstract Colorectal cancer (CRC), a complex and molecularly heterogenous disease that lacks robust predictive markers and targeted therapies, is the second…”
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