Search Results - "Emsley, Robin"

ChatGPT: these are not hallucinations – they’re fabrications and falsifications by Emsley, Robin

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Antipsychotics and structural brain changes: could treatment adherence explain the discrepant findings? by Emsley, Robin

“…Progressive structural brain changes are well documented in schizophrenia and have been linked to both illness progression and the extent of antipsychotic…”
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DNA methylation and antipsychotic treatment mechanisms in schizophrenia: Progress and future directions by Ovenden, Ellen S., McGregor, Nathaniel W., Emsley, Robin A., Warnich, Louise

“…Antipsychotic response in schizophrenia is a complex, multifactorial trait influenced by pharmacogenetic factors. With genetic studies thus far providing…”
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Safety of psychotropic medications in people with COVID-19: evidence review and practical recommendations by Ostuzzi, Giovanni, Papola, Davide, Gastaldon, Chiara, Schoretsanitis, Georgios, Bertolini, Federico, Amaddeo, Francesco, Cuomo, Alessandro, Emsley, Robin, Fagiolini, Andrea, Imperadore, Giuseppe, Kishimoto, Taishiro, Michencigh, Giulia, Nosé, Michela, Purgato, Marianna, Dursun, Serdar, Stubbs, Brendon, Taylor, David, Thornicroft, Graham, Ward, Philip B, Hiemke, Christoph, Correll, Christoph U, Barbui, Corrado

“…The novel coronavirus pandemic calls for a rapid adaptation of conventional medical practices to meet the evolving needs of such vulnerable patients. People…”
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The genetic architecture of schizophrenia, bipolar disorder, obsessive-compulsive disorder and autism spectrum disorder by O'Connell, Kevin S., McGregor, Nathaniel W., Lochner, Christine, Emsley, Robin, Warnich, Louise

“…Considerable evidence suggests that autism spectrum disorders (ASD), schizophrenia (SCZ), bipolar disorder (BD) and obsessive-compulsive disorder (OCD) share a…”
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Remission in early psychosis: Rates, predictors, and clinical and functional outcome correlates by Emsley, Robin, Rabinowitz, Jonathan, Medori, Rossella

“…Abstract Background Recently, the “Remission in Schizophrenia Working Group” proposed remission criteria consisting of a reduction to mild levels on key…”
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A systematic review of genetic variants associated with metabolic syndrome in patients with schizophrenia by Malan-Müller, Stefanie, Kilian, Sanja, van den Heuvel, Leigh L, Bardien, Soraya, Asmal, Laila, Warnich, Louise, Emsley, Robin A, Hemmings, Sîan M.J, Seedat, Soraya

“…Abstract Metabolic syndrome (MetS) is a cluster of factors that increases the risk of cardiovascular disease (CVD), one of the leading causes of mortality in…”
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Time Course for Antipsychotic Treatment Response in First-Episode Schizophrenia by Emsley, Robin, Rabinowitz, Jonathan, Medori, Rossella

“…Objective: The authors examined early onset of antipsychotic action and early prediction of nonresponse to antipsychotics in patients with first-episode…”
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Efficacy, safety and early response of paliperidone extended-release tablets (paliperidone ER): Results of a 6-week, randomized, placebo-controlled study by Davidson, Michael, Emsley, Robin, Kramer, Michelle, Ford, Lisa, Pan, Guohua, Lim, Pilar, Eerdekens, Mariëlle

“…Abstract Background Paliperidone extended-release tablet (paliperidone ER) is an oral psychotropic agent developed for schizophrenia treatment. Paliperidone…”
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Rate and predictors of non‐response to first‐line antipsychotic treatment in first‐episode schizophrenia by Chiliza, Bonginkosi, Asmal, Laila, Kilian, Sanja, Phahladira, Lebogang, Emsley, Robin

“…Objective The goals of this study were to (i) estimate the rate of non‐response to first‐line treatment in first‐episode schizophrenia, (ii) evaluate other…”
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Comparison of Treatment Response in Second-Episode Versus First-Episode Schizophrenia by EMSLEY, Robin, OOSTHUIZEN, Petrus, KOEN, Liezl, NIEHAUS, Dana, MARTINEZ, Lupe

“…This study investigated whether illness progression and treatment refractoriness emerge after relapse in schizophrenia. We compared outcomes in a cohort…”
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Factors associated with poor satisfaction with treatment and trial discontinuation in chronic schizophrenia by Schoemaker, Joep H., Vingerhoets, Ad J.J.M., Emsley, Robin A.

“…IntroductionDespite consistently high discontinuation rates due to withdrawal of consent (WOC) and insufficient therapeutic effect (ITE) in schizophrenia…”
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The factor structure for the Positive and Negative Syndrome Scale (PANSS) in recent-onset psychosis by Emsley, Robin, Rabinowitz, Jonathan, Torreman, Martijn

“…The Positive and Negative Syndrome Scale (PANSS) is a widely used instrument for measuring severe psychopathology in adult patients with schizophrenia. Data,…”
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Isolation rearing-induced deficits in sensorimotor gating and social interaction in rats are related to cortico-striatal oxidative stress, and reversed by sub-chronic clozapine administration by Möller, Marisa, Du Preez, Jan L, Emsley, Robin, Harvey, Brian H

“…Abstract Social isolation rearing (SIR) in rats induces behavioral and glutamatergic changes akin to schizophrenia. We studied the effects of 8 weeks SIR on…”
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Is the ongoing use of placebo in relapse-prevention clinical trials in schizophrenia justified? by Emsley, Robin, Fleischhacker, Wolfgang W

“…Abstract Background Placebo-controlled randomised controlled trials (RCTs) continue to be required or recommended by regulatory authorities for the licensing…”
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Causal attributions, pathway to care and clinical features of first-episode psychosis: A South African perspective by Burns, Jonathan K., Jhazbhay, Khatija, Emsley, Robin A.

“…Background: Causal belief systems and help-seeking practices may impact on pathway to care and features of first-episode psychosis (FEP) that have prognostic…”
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The concepts of remission and recovery in schizophrenia by Emsley, Robin, Chiliza, Bonginkosi, Asmal, Laila, Lehloenya, Keneilwa

“…PURPOSE OF REVIEWUntil recently outcome studies in schizophrenia lacked standardized measures, and outcome expectations were generally pessimistic. The…”
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Cognitive insight is associated with perceived body weight in overweight and obese adults by Suliman, Sharain, L van den Heuvel, Leigh, Kilian, Sanja, Bröcker, Erine, Asmal, Laila, Emsley, Robin, Seedat, Soraya

“…Accurate perception of body weight is necessary for individuals with a high body mass index (BMI) to initiate strategies to improve their health status…”
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Instruments measuring blunted affect in schizophrenia: a systematic review by Kilian, Sanja, Asmal, Laila, Goosen, Anneke, Chiliza, Bonginkosi, Phahladira, Lebogang, Emsley, Robin

“…Blunted affect, also referred to as emotional blunting, is a prominent symptom of schizophrenia. Patients with blunted affect have difficulty in expressing…”
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Risperidone and Haloperidol in First-Episode Psychosis: A Long-Term Randomized Trial by Schooler, Nina, Rabinowitz, Jonathan, Davidson, Michael, Emsley, Robin, Harvey, Philip D., Kopala, Lili, McGorry, Patrick D., Van Hove, Ilse, Eerdekens, Marielle, Swyzen, Wim, De Smedt, Goedele

“…OBJECTIVE: The first episode of psychotic illness is a key intervention point. The initial experience with medication can affect willingness to accept…”
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