Search Results - "Emsley, Hedley C."

Acute ischaemic stroke and infection: recent and emerging concepts by Emsley, Hedley CA, PhD, Hopkins, Stephen J, PhD

“…Summary The relation between acute ischaemic stroke and infection is complex. Infection appears to be an important trigger that precedes up to a third of…”
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HIV infection and stroke: current perspectives and future directions by Benjamin, Laura A, MRCP, Bryer, Alan, Prof, Emsley, Hedley CA, PhD, Khoo, Saye, MD, Solomon, Tom, Prof, Connor, Myles D, Dr

“…Summary HIV infection can result in stroke via several mechanisms, including opportunistic infection, vasculopathy, cardioembolism, and coagulopathy. However,…”
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Blood-Brain Barrier Leakage Is Increased in Parkinson's Disease by Al-Bachari, Sarah, Naish, Josephine H, Parker, Geoff J M, Emsley, Hedley C A, Parkes, Laura M

“…Blood-brain barrier (BBB) disruption has been noted in animal models of Parkinson's disease (PD) and forms the basis of the vascular hypothesis of…”
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A Systematic Review of Glucose Transport Alterations in Alzheimer's Disease by Kyrtata, Natalia, Emsley, Hedley C A, Sparasci, Oli, Parkes, Laura M, Dickie, Ben R

“…Alzheimer's disease (AD) is characterized by cerebral glucose hypometabolism. Hypometabolism may be partly due to reduced glucose transport at the blood-brain…”
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Routinely collected patient data in neurology research: a systematic mapping review by Biggin, Fran, Emsley, Hedley C A, Knight, Jo

“…This review focuses on neurology research which uses routinely collected data. The number of such studies is growing alongside the expansion of data…”
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Late-Onset Epilepsy and Occult Cerebrovascular Disease by Gibson, Lorna M, Hanby, Martha F, Al-Bachari, Sarah M, Parkes, Laura M, Allan, Stuart M, Emsley, Hedley CA

“…The interface between cerebrovascular disease (CVD) and epilepsy is complex and multifaceted. Late-onset epilepsy (LOE) is increasingly common and is often…”
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The incidence of acute encephalitis syndrome in Western industrialised and tropical countries by Jmor, Fidan, Emsley, Hedley C A, Fischer, Marc, Solomon, Tom, Lewthwaite, Penny

“…As part of efforts to control Japanese encephalitis (JE), the World Health Organization is producing a set of standards for JE surveillance, which require the…”
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Calibrated fMRI during a cognitive Stroop task reveals reduced metabolic response with increasing age by Mohtasib, Rafat S., Lumley, Guy, Goodwin, Jonathan A., Emsley, Hedley C.A., Sluming, Vanessa, Parkes, Laura M.

“…fMRI studies of aging have revealed increased blood oxygenation level dependent (BOLD) response to tasks of executive function with advancing age, which is…”
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Titin founder mutation is a common cause of myofibrillar myopathy with early respiratory failure by Pfeffer, Gerald, Barresi, Rita, Wilson, Ian J, Hardy, Steven A, Griffin, Helen, Hudson, Judith, Elliott, Hannah R, Ramesh, Aravind V, Radunovic, Aleksandar, Winer, John B, Vaidya, Sujit, Raman, Ashok, Busby, Mark, Farrugia, Maria E, Ming, Alec, Everett, Chris, Emsley, Hedley C A, Horvath, Rita, Straub, Volker, Bushby, Kate, Lochmüller, Hanns, Chinnery, Patrick F, Sarkozy, Anna

“…Objective Titin gene (TTN) mutations have been described in eight families with hereditary myopathy with early respiratory failure (HMERF). Some of the…”
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Interleukin-1 receptor antagonist treatment in acute ischaemic stroke does not alter systemic markers of anti-microbial defence [version 2; peer review: 2 approved] by McCulloch, Laura, Allan, Stuart M, Emsley, Hedley C, Smith, Craig J, McColl, Barry W

“…Background: Blockade of the cytokine interleukin-1 (IL-1) with IL-1 receptor antagonist (IL-1Ra) is a candidate treatment for stroke entering phase II/III…”
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Numbers and types of neurological emergencies in England and the influence of socioeconomic deprivation: a retrospective analysis of hospital episode statistics data by Jackson, Michael, Szczepaniak, Marta, Wall, Jasmine, Maskery, Mark, Mummery, Catherine, Morrish, Paul, Williams, Adrian, Knight, Joanne, Emsley, Hedley C A

“…ObjectivesIn this first large-scale analysis of neurological emergency admissions in England, we determine the number and types of emergency admissions with…”
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Peak plasma interleukin-6 and other peripheral markers of inflammation in the first week of ischaemic stroke correlate with brain infarct volume, stroke severity and long-term outcome by Smith, Craig J, Emsley, Hedley C A, Gavin, Carole M, Georgiou, Rachel F, Vail, Andy, Barberan, Elisa M, del Zoppo, Gregory J, Hallenbeck, John M, Rothwell, Nancy J, Hopkins, Stephen J, Tyrrell, Pippa J

“…Cerebral ischaemia initiates an inflammatory response in the brain and periphery. We assessed the relationship between peak values of plasma interleukin-6…”
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Evaluation of C-reactive protein measurement for assessing the risk and prognosis in ischemic stroke : A statement for health care professionals from the CRP pooling project members by DI NAPOLI, Mario, SCHWANINGER, Markus, MUIR, Keith W, PACIUCCI, Anna, PAPA, Francesca, RONCACCI, Sabina, SANDER, Dirk, SANDER, Kerstin, SMITH, Craig J, STEFANINI, Alessandro, WEBER, Daniela, CAPPELLI, Roberto, CECCARELLI, Elena, DI GIANFILIPPO, Giacinto, DONATI, Cristina, EMSLEY, Hedley C. A, FORCONI, Sandro, HOPKINS, Stephen J, MASOTTI, Luca

“…Several studies have shown, in different populations, that modest elevation of plasma C-reactive protein (CRP) in the range seen in apparently healthy…”
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Urgent referral for suspected CNS cancer: which clinical features are associated with a positive predictive value of 3 % or more? by Mohammad, Hasan Raza, Boardman, Jeremy, Howell, Laura, Mills, Roger J, Emsley, Hedley C A

“…Urgent referral for suspected central nervous system (CNS) cancer is recommended, but little analysis of the referral criteria diagnostic performance has been…”
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Inflammation in Acute Ischemic Stroke and its Relevance to Stroke Critical Care by Emsley, Hedley C. A., Smith, Craig J., Tyrrell, Pippa J., Hopkins, Stephen J.

“…Thrombolysis heralded a new era of acute intervention for ischemic stroke, accompanied by an increasing need for comprehensive acute critical care support…”
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Variation in waiting times by diagnostic category: an observational study of 1,951 referrals to a neurology outpatient clinic by Biggin, Fran, Howcroft, Timothy, Davies, Quinta, Knight, Jo, Emsley, Hedley C A

“…ObjectiveTo investigate the frequency of diagnoses seen among new referrals to neurology outpatient services; to understand how these services are used through…”
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Myasthenia gravis as a ‘stroke mimic’ – it’s all in the history by Shaik, Saiffuddin, Ul-Haq, Mian Ayaz, Emsley, Hedley CA

“…An 85-year-old man presented to hospital as an emergency having difficulties with swallowing and speech. In the emergency department, he was assessed as having…”
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Integrating acute stroke telemedicine consultations into specialists' usual practice: a qualitative analysis comparing the experience of Australia and the United Kingdom by Bagot, Kathleen L, Cadilhac, Dominique A, Bladin, Christopher F, Watkins, Caroline L, Vu, Michelle, Donnan, Geoffrey A, Dewey, Helen M, Emsley, Hedley C A, Davies, D Paul, Day, Elaine, Ford, Gary A, Price, Christopher I, May, Carl R, McLoughlin, Alison S R, Gibson, Josephine M E, Lightbody, Catherine E

“…Stroke telemedicine can reduce healthcare inequities by increasing access to specialists. Successful telemedicine networks require specialists adapting…”
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Neurological symptoms in a post-transplant patient: a cautionary tale by Chhetri, Suresh Kumar, Dayanandan, Rejith, Jacob, Joseph, Sonwalkar, Hemant, Ahmed, Aimun, Kumar, Varadarajan, Emsley, Hedley C. A.

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Validation of ICD-10 codes shows intracranial venous thrombosis incidence to be higher than previously reported by Handley, Joel D, Emsley, Hedley CA

“…Background: Intracranial venous thrombosis (ICVT) accounts for around 0.5% of all stroke cases. There have been no previously published studies of the…”
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