Search Results - "Emmens, Johanna E"
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Plasma kidney injury molecule-1 in heart failure: renal mechanisms and clinical outcome
Published in European journal of heart failure (01-06-2016)“…Aims Urinary kidney injury molecule‐1 (KIM‐1) is a marker of tubular damage and associated with worse outcome in heart failure (HF). Plasma KIM‐1 has not been…”
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Impaired High-Density Lipoprotein Function in Patients With Heart Failure
Published in Journal of the American Heart Association (04-05-2021)“…Background We recently showed that, in patients with heart failure, lower high-density lipoprotein (HDL) cholesterol concentration was a strong predictor of…”
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Albuminuria as a marker of systemic congestion in patients with heart failure
Published in European heart journal (01-02-2023)“…Albuminuria is common in patients with heart failure and associated with worse outcomes. The underlying pathophysiological mechanism of albuminuria in heart…”
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Worsening renal function in acute heart failure in the context of diuretic response
Published in European journal of heart failure (01-02-2022)“…Background For patients with acute heart failure (AHF), substantial diuresis after administration of loop diuretics is generally associated with better…”
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Sex disparities in the effect of statins on lipid parameters: The PharmLines Initiative
Published in Medicine (Baltimore) (14-01-2022)“…Real-world evidence on a potential statin effect modification by sex is inconclusive, especially for the primary prevention of cardiovascular disease (CVD). We…”
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Clinical value of pre‐discharge bio‐adrenomedullin as a marker of residual congestion and high risk of heart failure hospital readmission
Published in European journal of heart failure (01-04-2020)“…Aims Recently, bio‐adrenomedullin (bio‐ADM) was proposed as a congestion marker in heart failure (HF). In the present study, we aimed to study whether bio‐ADM…”
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Multiomics Analysis Provides Novel Pathways Related to Progression of Heart Failure
Published in Journal of the American College of Cardiology (14-11-2023)“…BACKGROUNDDespite major advances in pharmacological treatment for patients with heart failure, residual mortality remains high. This suggests that important…”
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Association between adherence to statin therapy and low-density lipoprotein cholesterol (LDL-c) response in first-time users of standard-dose and low-dose statins: the PharmLines initiative
Published in Current medical research and opinion (2022)“…To investigate whether statin adherence (defined as proportion days covered, PDC) is associated with LDL-c response in statin initiators on standard and low…”
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Assessment of Proximal Tubular Function by Tubular Maximum Phosphate Reabsorption Capacity in Heart Failure
Published in Clinical journal of the American Society of Nephrology (01-02-2022)“…The estimated glomerular filtration rate (eGFR) is a crucial parameter in heart failure. Much less is known about the importance of tubular function. We…”
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Biomarker signature and pathophysiological pathways in patients with chronic heart failure and metabolic syndrome
Published in European journal of heart failure (01-02-2023)“…Aim The comorbidities that collectively define metabolic syndrome are common in patients with heart failure. However, the role of metabolic syndrome in the…”
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Are circulating relaxin levels related to pulmonary hypertension in patients with heart failure?
Published in European journal of heart failure (01-07-2017)Get full text
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Proenkephalin, an Opioid System Surrogate, as a Novel Comprehensive Renal Marker in Heart Failure
Published in Circulation. Heart failure (01-05-2019)“…PENK (proenkephalin) is a stable surrogate for enkephalins, endogenous opioid peptides, which exert cardiodepressive effects and improve renal function. PENK…”
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Proenkephalin and the risk of new‐onset heart failure: data from prevention of renal and vascular end‐stage disease
Published in Clinical cardiology (Mahwah, N.J.) (01-12-2021)“…Background Enkephalins of the opioid system exert several cardiorenal effects. Proenkephalin (PENK), a stable surrogate, is associated with heart failure (HF)…”
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The influence of atrial fibrillation on the levels of NT-proBNP versus GDF-15 in patients with heart failure
Published in Clinical research in cardiology (01-03-2020)“…Background In heart failure (HF), levels of NT-proBNP are influenced by the presence of concomitant atrial fibrillation (AF), making it difficult to…”
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Systemic oxidative stress associates with disease severity and outcome in patients with new-onset or worsening heart failure
Published in Clinical research in cardiology (01-08-2023)“…Background Oxidative stress may be a key pathophysiological mediator in the development and progression of heart failure (HF). The role of serum-free thiol…”
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Correction to: The influence of atrial fibrillation on the levels of NT-proBNP versus GDF-15 in patients with heart failure
Published in Clinical research in cardiology (01-08-2021)“…The original article can be found online…”
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Multi-omics analysis provides novel pathways related to progression of heart failure
Published in Journal of the American College of Cardiology (14-11-2023)Get full text
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18
Association between adherence to statin therapy and low-density lipoprotein cholesterol (LDL-c) response in first-time users of standard-dose and low-dose statins: the PharmLines initiative
Published in Current Medical Research and Opinion (02-01-2022)“…To investigate whether statin adherence (defined as proportion days covered, PDC) is associated with LDL-c response in statin initiators on standard and low…”
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