Search Results - "Emmanuel Barbier"

ImUnity: A generalizable VAE-GAN solution for multicenter MR image harmonization by Cackowski, Stenzel, Barbier, Emmanuel L., Dojat, Michel, Christen, Thomas

“…ImUnity is an original 2.5D deep-learning model designed for efficient and flexible MR image harmonization. A VAE-GAN network, coupled with a confusion module…”
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Treating early postnatal circuit defect delays Huntington's disease onset and pathology in mice by Braz, Barbara Yael, Wennagel, Doris, Ratié, Leslie, de Souza, Diego Alves Rodrigues, Deloulme, Jean Christophe, Barbier, Emmanuel L, Buisson, Alain, Lanté, Fabien, Humbert, Sandrine

“…Recent evidence has shown that even mild mutations in the Huntingtin gene that are associated with late-onset Huntington's disease (HD) disrupt various aspects…”
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Brain metabolism in tau and amyloid mouse models of Alzheimer's disease: An MRI study by Wei, Zhiliang, Xu, Jiadi, Chen, Lin, Hirschler, Lydiane, Barbier, Emmanuel L., Li, Tong, Wong, Philip C., Lu, Hanzhang

“…Alzheimer's disease (AD) is the leading cause of cognitive impairment and dementia in elderly individuals. According to the current biomarker framework for…”
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Re-routing Metabolism by the Mitochondrial Pyruvate Carrier Inhibitor MSDC-0160 Attenuates Neurodegeneration in a Rat Model of Parkinson’s Disease by Mallet, David, Goutaudier, Raphael, Barbier, Emmanuel L., Carnicella, Sebastien, Colca, Jerry R., Fauvelle, Florence, Boulet, Sabrina

“…A growing body of evidence supports the idea that mitochondrial dysfunction might represent a key feature of Parkinson’s disease (PD). Central regulators of…”
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Functional connectivity is preserved but reorganized across several anesthetic regimes by Becq, Guillaume J.-P. C., Habet, Tarik, Collomb, Nora, Faucher, Margaux, Delon-Martin, Chantal, Coizet, Véronique, Achard, Sophie, Barbier, Emmanuel L.

“…Under anesthesia, systemic variables and CBF are modified. How does this alter the connectivity measures obtained with rs-fMRI? To tackle this question, we…”
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A metabolic biomarker predicts Parkinson's disease at the early stages in patients and animal models by Mallet, David, Dufourd, Thibault, Decourt, Mélina, Carcenac, Carole, Bossù, Paola, Verlin, Laure, Fernagut, Pierre-Olivier, Benoit-Marand, Marianne, Spalletta, Gianfranco, Barbier, Emmanuel L, Carnicella, Sebastien, Sgambato, Véronique, Fauvelle, Florence, Boulet, Sabrina

“…BackgroundCare management of Parkinson's disease (PD) patients currently remains symptomatic, mainly because diagnosis relying on the expression of the…”
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PIEZO1 expression at the glio-vascular unit adjusts to neuroinflammation in seizure conditions by Garcia, Valentin, Blaquiere, Marine, Janvier, Alicia, Cresto, Noemie, Lana, Carla, Genin, Athenais, Hirbec, Helene, Audinat, Etienne, Faucherre, Adele, Barbier, Emmanuel L., Hamelin, Sophie, Kahane, Philippe, Jopling, Chris, Marchi, Nicola

“…Mechanosensors are emerging players responding to hemodynamic and physical inputs. Their significance in the central nervous system remains relatively…”
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A pericyte‐glia scarring develops at the leaky capillaries in the hippocampus during seizure activity by Klement, Wendy, Blaquiere, Marine, Zub, Emma, deBock, Frederic, Boux, Fabien, Barbier, Emmanuel, Audinat, Etienne, Lerner‐Natoli, Mireille, Marchi, Nicola

“…Objective Inflammatory cerebrovascular damage occurs in epilepsy. Here, we tested the hypothesis that a pericyte‐glia scar forms around the outer wall of…”
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High‐resolution perfusion imaging in rodents using pCASL at 9.4 T by Pires Monteiro, Sara, Hirschler, Lydiane, Barbier, Emmanuel L., Figueiredo, Patricia, Shemesh, Noam

“…Adequate perfusion is critical for maintaining normal brain function and aberrations thereof are hallmarks of many diseases. Pseudo‐Continuous Arterial Spin…”
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Bayesian Inverse Regression for Vascular Magnetic Resonance Fingerprinting by Boux, Fabien, Forbes, Florence, Arbel, Julyan, Lemasson, Benjamin, Barbier, Emmanuel L.

“…Standard parameter estimation from vascular magnetic resonance fingerprinting (MRF) data is based on matching the MRF signals to their best counterparts in a…”
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In vivo γ‐aminobutyric acid increase as a biomarker of the epileptogenic zone: An unbiased metabolomics approach by Hamelin, Sophie, Stupar, Vasile, Mazière, Lucile, Guo, Jia, Labriji, Wafae, Liu, Chen, Bretagnolle, Ludiwine, Parrot, Sandrine, Barbier, Emmanuel L., Depaulis, Antoine, Fauvelle, Florence

“…Objective Following surgery, focal seizures relapse in 20% to 50% of cases due to the difficulty of delimiting the epileptogenic zone (EZ) by current imaging…”
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EEG-fMRI in awake rat and whole-brain simulations show decreased brain responsiveness to sensory stimulations during absence seizures by Stenroos, Petteri, Guillemain, Isabelle, Tesler, Federico, Montigon, Olivier, Collomb, Nora, Stupar, Vasile, Destexhe, Alain, Coizet, Veronique, David, Olivier, Barbier, Emmanuel L

“…In patients suffering absence epilepsy, recurring seizures can significantly decrease their quality of life and lead to yet untreatable comorbidities. Absence…”
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Prediction of therapeutic intensity level from automatic multiclass segmentation of traumatic brain injury lesions on CT-scans by Brossard, Clément, Grèze, Jules, de Busschère, Jules-Arnaud, Attyé, Arnaud, Richard, Marion, Tornior, Florian Dhaussy, Acquitter, Clément, Payen, Jean-François, Barbier, Emmanuel L., Bouzat, Pierre, Lemasson, Benjamin

“…The prediction of the therapeutic intensity level (TIL) for severe traumatic brain injury (TBI) patients at the early phase of intensive care unit (ICU)…”
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Evaluation of kernel low-rank compressed sensing in preclinical diffusion magnetic resonance imaging by de Souza, Diego Alves Rodrigues, Mathieu, Hervé, Deloulme, Jean-Christophe, Barbier, Emmanuel L

“…Compressed sensing (CS) is widely used to accelerate clinical diffusion MRI acquisitions, but it is not widely used in preclinical settings yet. In this study,…”
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Evidence of cerebral hypoperfusion consecutive to ultrasound‐mediated blood‐brain barrier opening in rats by Labriji, Wafae, Clauzel, Julien, Mestas, Jean‐Louis, Lafond, Maxime, Lafon, Cyril, Salabert, Anne‐Sophie, Hirschler, Lydiane, Warnking, Jan M., Barbier, Emmanuel L., Loubinoux, Isabelle, Desmoulin, Franck

“…Purpose This work aims to explore the effect of Blood Brain Barrier (BBB) opening using ultrasound combined with microbubbles injection on cerebral blood flow…”
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Fully Automatic Lesion Localization and Characterization: Application to Brain Tumors Using Multiparametric Quantitative MRI Data by Arnaud, Alexis, Forbes, Florence, Coquery, Nicolas, Collomb, Nora, Lemasson, Benjamin, Barbier, Emmanuel L.

“…When analyzing brain tumors, two tasks are intrinsically linked, spatial localization, and physiological characterization of the lesioned tissues. Automated…”
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SAR comparison between CASL and pCASL at high magnetic field and evaluation of the benefit of a dedicated labeling coil by Hirschler, Lydiane, Collomb, Nora, Voiron, Jérôme, Köhler, Sascha, Barbier, Emmanuel L., Warnking, Jan M.

“…Purpose To investigate the heating induced by (pseudo)‐continuous arterial spin labeling ((p)CASL) sequences in vivo at 9.4T and to evaluate the benefit of a…”
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Gadolinium-Based Nanoparticles and Radiation Therapy for Multiple Brain Melanoma Metastases: Proof of Concept before Phase I Trial by Kotb, Shady, Detappe, Alexandre, Lux, François, Appaix, Florence, Barbier, Emmanuel L, Tran, Vu-Long, Plissonneau, Marie, Gehan, Hélène, Lefranc, Florence, Rodriguez-Lafrasse, Claire, Verry, Camille, Berbeco, Ross, Tillement, Olivier, Sancey, Lucie

“…Nanoparticles containing high-Z elements are known to boost the efficacy of radiation therapy. Gadolinium (Gd) is particularly attractive because this element…”
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Optimized cervical spinal cord perfusion MRI after traumatic injury in the rat by Meyer, Briana P, Hirschler, Lydiane, Lee, Seongtaek, Kurpad, Shekar N, Warnking, Jan M, Barbier, Emmanuel L, Budde, Matthew D

“…Despite the potential to guide clinical management of spinal cord injury and disease, noninvasive methods of monitoring perfusion status of the spinal cord…”
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Neurovascular multiparametric MRI defines epileptogenic and seizure propagation regions in experimental mesiotemporal lobe epilepsy by Boux, Fabien, Forbes, Florence, Collomb, Nora, Zub, Emma, Mazière, Lucile, Bock, Fréderic, Blaquiere, Marine, Stupar, Vasile, Depaulis, Antoine, Marchi, Nicola, Barbier, Emmanuel L.

“…Objective Improving the identification of the epileptogenic zone and associated seizure‐spreading regions represents a significant challenge. Innovative…”
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