Search Results - "Emma, Sarah E"

Estrogen receptor blockade and radiation therapy cooperate to enhance the response of immunologically cold ER+ breast cancer to immunotherapy by O'Leary, Kathleen A, Bates, Amber M, Jin, Won Jong, Burkel, Brian M, Sriramaneni, Raghava N, Emma, Sarah E, Nystuen, Erin J, Sumiec, Elizabeth G, Ponik, Suzanne M, Morris, Zachary S, Schuler, Linda A

“…Most patients with estrogen receptor positive (ER+) breast cancer do not respond to immune checkpoint inhibition (ICI); the tumor microenvironment (TME) of…”
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Temporal analysis of type 1 interferon activation in tumor cells following external beam radiotherapy or targeted radionuclide therapy by Jagodinsky, Justin C, Jin, Won Jong, Bates, Amber M, Hernandez, Reinier, Grudzinski, Joseph J, Marsh, Ian R, Chakravarty, Ishan, Arthur, Ian S, Zangl, Luke M, Brown, Ryan J, Nystuen, Erin J, Emma, Sarah E, Kerr, Caroline, Carlson, Peter M, Sriramaneni, Raghava N, Engle, Jonathan W, Aluicio-Sarduy, Eduardo, Barnhart, Todd E, Le, Trang, Kim, KyungMann, Bednarz, Bryan P, Weichert, Jamey P, Patel, Ravi B, Morris, Zachary S

“…Clinical interest in combining targeted radionuclide therapies (TRT) with immunotherapies is growing. External beam radiation therapy (EBRT) activates a type 1…”
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Abstract 676: Fulvestrant and radiation modify the tumor immune microenvironment in ER+ metastatic breast cancer and cooperate to enhance response to anti-PDL1 checkpoint blockade by Nystuen, Erin J., Bates, Amber M., O'Leary, Kathleen A., Emma, Sarah E., Sumiec, Elizabeth G., Schuler, Linda A., Morris, Zachary S.

“…Abstract Metastatic, hormone therapy-resistant breast cancers expressing estrogen receptor (ER+) account for most breast cancer deaths. A lack of…”
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Abstract 508: Mechanisms of cooperative response to bempegaldesleukin (BEMPEG) and 90Y-NM600 targeted radionuclide therapy in the treatment of a syngeneic murine model of head and neck squamous cell carcinoma by Emma, Sarah E., Bates, Amber M., Hernandez, Reinier, Grudzinski, Joseph J., Marsh, Ian R., Jagodinsky, Justin C., Bednarz, Bryan P., Pieper, Alexander A., Sumiec, Elizabeth G., Nystuen, Erin J., Sosa, Gustavo A., Patel, Ravi B., Weichert, Jamey, Morris, Zachary S.

“…Abstract The purpose of this study was to evaluate mechanisms of cooperative therapeutic effects of bempegaldesleukin (BEMPEG; NKTR-214) and 90Y-NM600 in head…”
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Abstract 679: In vivo synergy of 90Y-NM600 and Bempegaldesleukin improves anti-tumor efficacy of immune checkpoint inhibitors in syngeneic murine cancer models by Sumiec, Elizabeth G., Bates, Amber M., Hernandez, Reinier, Grudzinski, Joseph J., Marsh, Ian R., Emma, Sarah E., Nystuen, Erin J., Jagodinsky, Justin C., Pieper, Alexander A., Sosa, Gustavo A., Bednarz, Bryan P., Patel, Ravi B., Weichert, Jamey, Morris, Zachary S.

“…Abstract We have observed in preclinical studies that the delivery of low dose targeted radionuclide therapy (TRT) therapy to sites of primary and metastatic…”
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Abstract 3060: Temporal analysis of type 1 interferon activation in tumor cells following external beam radiotherapy or targeted radionuclide therapy by Jagodinsky, Justin C., Bates, Amber M., Hernandez, Reinier, Grudzinski, Joseph J., Marsh, Ian R., Chakravarty, Ishan, Arthur, Ian S., Zangl, Luke M., Brown, Ryan J., Nystuen, Erin J., Emma, Sarah E., Kerr, Caroline, Jin, Won Jong, Carlson, Peter M., Engle, Jonathan W., Aluicio-Sarduy, Eduardo, Barnhart, Todd E., Le, Trang, Kim, KyungMann, Bednarz, Bryan P., Weichert, Jamey P., Patel, Ravi B., Morris, Zachary S.

“…Abstract Background: Radiation (RT) activates a type 1 interferon (IFN1) response and this is critical to the effect of RT in priming a response to immune…”
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PP13 Presentation Time: 3:30 PM by Jagodinsky, Justin Charles, Chakravarty, Ishan, Jin, Wonjong J., Sriramaneni, Raghava N., Clark, Paul A., Emma, Sarah E., Arthur, Ian S., Lan, Keng-Hsueh S., Das, Rupak K., Miller, Jessica R., Morris, Zachary S.

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PP13 Presentation Time: 3:30 PM: Brachytherapy Dose Heterogeneity Turns Cold Tumors Hot by Jagodinsky, Justin Charles, Chakravarty, Ishan, Jin, Wonjong J., Sriramaneni, Raghava N., Clark, Paul A., Emma, Sarah E., Arthur, Ian S., Lan, Keng-Hsueh S., Das, Rupak K., Miller, Jessica R., Morris, Zachary S.

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Abstract 1304: Brachytherapy dose heterogeneity primes response to immune checkpoint blockade to generate anti-tumor immunity by Jagodinsky, Justin C., Jin, Wonjong, Vera, Jessica M., Sriramaneni, Raghava N., Clark, Paul A., Lan, Keng-Hsueh S., Chakravarty, Ishan, Siegel, Noah, Allawi, Raad H., Emma, Sarah E., Arthur, Ian S., Das, Rupak K., Ong, Irene M., Miller, Jessica R., Morris, Zachary S.

“…Abstract Purpose: The immunologic effects of radiation (RT) are influenced by dose and each may be optimized over a unique dose range. We used brachytherapy…”
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