Normocalcemic hyperparathyroidism presented with mandibular brown tumor: report of a case

Brown tumor is a rare clinical entity complicating hyperparathyroidism. It may occur in the head and neck, with the mandible being the most frequent site. Hyperparathyroidism is usually associated with hypercalcemia. We report a case of madibular Brown tumor secondary to primary hyperparathyroidism....

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Bibliographic Details
Published in:	Auris, nasus, larynx Vol. 31; no. 3; pp. 299 - 304
Main Authors:	Emin, A.Haluk, Süoğlu, Yusufhan, Demir, Deniz, Karatay, Mesut Can
Format:	Journal Article
Language:	English
Published:	Netherlands Elsevier Ireland Ltd 01-09-2004
Subjects:	Biopsy, Needle Brown tumor Calcium - blood Calcium - metabolism Female Humans Hyperparathyroidism Hyperparathyroidism - complications Hyperparathyroidism - diagnosis Hyperparathyroidism - metabolism Magnetic Resonance Imaging Mandibular Diseases - complications Mandibular Diseases - diagnosis Mandibular Diseases - surgery Mandibular mass Middle Aged Terminology as Topic Tomography, X-Ray Computed Brown tumor Mandibular mass Hyperparathyroidism
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Summary:	Brown tumor is a rare clinical entity complicating hyperparathyroidism. It may occur in the head and neck, with the mandible being the most frequent site. Hyperparathyroidism is usually associated with hypercalcemia. We report a case of madibular Brown tumor secondary to primary hyperparathyroidism. In this case in spite of hyperparathyroidism and the bony lesion the serum calcium level was within normal range. The case managed by surgical excision of the mandibular tumor with an en-bloc hemithyroidectomy with inclusion of the diseased parathyroid gland. This case demonstrates that in osteolytic bony lesions a hyperparathyroid complication can be expected even with normal serum calcium level. The presence of normocalcemia in primary hyperparathyroidism should prompt the physician to look for vitamin D deficiency.
Bibliography:	ObjectType-Case Study-2 SourceType-Scholarly Journals-1 ObjectType-Feature-4 content type line 23 ObjectType-Report-1 ObjectType-Article-3
ISSN:	0385-8146 1879-1476
DOI:	10.1016/j.anl.2004.03.014