Search Results - "Emilsson, V."

Expression of the functional leptin receptor mRNA in pancreatic islets and direct inhibitory action of leptin on insulin secretion by Emilsson, V., Liu, Y. L., Cawthorne, M. A., Morton, N. M., Davenport, M.

“…Expression of the functional leptin receptor mRNA in pancreatic islets and direct inhibitory action of leptin on insulin secretion. V Emilsson , Y L Liu , M A…”
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Fetal pancreatic islets express functional leptin receptors and leptin stimulates proliferation of fetal islet cells by Islam, M.S, Sjoholm, A, Emilsson, V

“…OBJECTIVE: Previous studies have demonstrated that leptin can stimulate proliferation of insulin-secreting tumor cell lines. The objective of this study was to…”
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Leptin signalling in pancreatic islets and clonal insulin-secreting cells by Morton, NM, Emilsson, V, de Groot, P, Pallett, AL, Cawthorne, MA

“…Leptin is a cytokine secreted from adipose tissue at a rate commensurate with the size of the body's fat stores. In addition to its anorectic and thermogenic…”
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Factor for inversion stimulation-dependent growth rate regulation of individual tRNA species in Escherichia coli by NILSSON, L, EMILSSON, V

“…We have studied the involvement of the factor for inversion stimulation (FIS) in the growth rate-dependent expression of the arginine, leucine, and methionine…”
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Growth rate dependence of transfer RNA abundance in Escherichia coli by Emilsson, V., Kurland, C. G.

“…We have tested the predictions of a model that accounts for the codon preferences of bacteria in terms of a growth maximization strategy. According to this…”
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Oncostatin M reduces atherosclerosis development in APOE3Leiden.CETP mice and is associated with increased survival probability in humans by Keulen, Danielle van, Pouwer, Marianne G, Emilsson, Valur, Matic, Ljubica Perisic, Pieterman, Elsbet J, Hedin, Ulf, Gudnason, Vilmundur, Jennings, Lori L, Holmstrøm, Kim, Nielsen, Boye Schnack, Pasterkamp, Gerard, Lindeman, Jan H N, van Gool, Alain J, Sollewijn Gelpke, Maarten D, Princen, Hans M G, Tempel, Dennie

“…Previous studies indicate a role for Oncostatin M (OSM) in atherosclerosis and other chronic inflammatory diseases for which inhibitory antibodies are in…”
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On the Replication of Genetic Associations: Timing Can Be Everything by Lasky-Su, Jessica, Lyon, Helen N., Emilsson, Valur, Heid, Iris M., Molony, Cliona, Raby, Benjamin A., Lazarus, Ross, Klanderman, Barbara, Soto-Quiros, Manuel E., Avila, Lydiana, Silverman, Edwin K., Thorleifsson, Gudmar, Thorsteinsdottir, Unnur, Kronenberg, Florian, Vollmert, Caren, Illig, Thomas, Fox, Caroline S., Levy, Daniel, Laird, Nan, Ding, Xiao, McQueen, Matt B., Butler, Johannah, Ardlie, Kristin, Papoutsakis, Constantina, Dedoussis, George, O'Donnell, Christopher J., Wichmann, H.-Erich, Celedón, Juan C., Schadt, Eric, Hirschhorn, Joel, Weiss, Scott T., Stefansson, Kari, Lange, Christoph

“…The failure of researchers to replicate genetic-association findings is most commonly attributed to insufficient statistical power, population stratification,…”
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Integrated Human Evaluation of the Lysophosphatidic Acid Pathway as a Novel Therapeutic Target in Atherosclerosis by Aldi, Silvia, Matic, Ljubica Perisic, Hamm, Gregory, van Keulen, Daniëlle, Tempel, Dennie, Holmstrøm, Kim, Szwajda, Agnieszka, Nielsen, Boye Schnack, Emilsson, Valur, Ait-Belkacem, Rima, Lengquist, Mariette, Paulsson-Berne, Gabrielle, Eriksson, Per, Lindeman, Jan H.N., Gool, Alain J., Stauber, Jonathan, Hedin, Ulf, Hurt-Camejo, Eva

“…Variants in the PLPP3 gene encoding for lipid phosphate phosphohydrolase 3 have been associated with susceptibility to atherosclerosis independently of…”
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Expression of the functional leptin receptor mRNA in pancreatic islets and direct inhibitory action of leptin on insulin secretion by EMILSSON, V, LIU, Y.-L, CAWTHORNE, M. A, MORTON, N. M, DAVENPORT, M

“…Leptin, encoded for by the mouse ob gene, regulates feeding behavior and energy metabolism. Its receptor (Ob-R) is encoded by the mouse diabetic (db) gene and…”
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Leptin Action in Intestinal Cells by Morton, Nicholas M., Emilsson, Valur, Liu, Yong-Ling, Cawthorne, Michael A.

“…The adipocyte hormone leptin activates signal transducer and activator of transcription 3 (STAT3) in the hypothalamus, mediating increased satiety and…”
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Leptin Inhibits Insulin Secretion and Reduces Insulin mRNA Levels in Rat Isolated Pancreatic Islets by Pallett, Anna L., Morton, Nicholas M., Cawthorne, Michael A., Emilsson, Valur

“…The ob gene product leptin over the concentration range 0.1–100nM demonstrated a U-shaped dose–response inhibition of glucose-stimulated insulin secretion by…”
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Leptin inhibits glycogen synthesis in the isolated soleus muscle of obese (ob/ob) mice by Liu, Yong-Ling, Emilsson, Valur, Cawthorne, Michael A.

“…The ob gene product, leptin, causes significant and dose-dependent inhibition of basal and insulin-stimulated glycogen synthesis in isolated soleus muscle from…”
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Leptin treatment increases suppressors of cytokine signaling in central and peripheral tissues by Emilsson, Valur, Arch, Jonathan R.S., de Groot, Rolf P., Lister, Carolyn A., Cawthorne, Michael A.

“…Leptin concentrations are elevated in the majority of obese individuals raising the possibility that leptin resistance contributes to their obesity. Peripheral…”
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Hexosamines and nutrient excess induce leptin production and leptin receptor activation in pancreatic islets and clonal beta-cells by Emilsson, V, O'Dowd, J, Nolan, A L, Cawthorne, M A

“…Activation of the hexosamine biosynthesis pathway leads to insulin resistance in muscle and adipose tissue. In these tissues leptin gene expression is…”
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Fetal pancreatic islets express functional i leptin receptors and leptin stimulates proliferation of fetal islet cells by ISLAM, M. S, SJÖHOLM, A, EMILSSON, V

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Rat Insulinoma-Derived Pancreatic β-cells Express a Functional Leptin Receptor That Mediates a Proliferative Response by Islam, Md.Shahidul, Morton, Nicholas M., Hansson, Anders, Emilsson, Valur

“…In addition to its interaction at hypothalamic sites to affect feeding and energy expenditure, leptin has been shown to exhibit a proliferative response in…”
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FACTOR FOR INVERSION STIMULATION-DEPENDENT GROWTH-RATE REGULATION OF SERINE AND THREONINE TRANSFER-RNA SPECIES by EMILSSON, V, NILSSON, L

“…We have previously shown that the accumulation of 20 tRNA species in Escherichia coli is individually regulated as a function of cellular growth rate. We have…”
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Hexosamines and Nutrient Excess Induce Leptin Production and Leptin Receptor Activation in Pancreatic Islets and Clonalβ -Cells by Emilsson, Valur, O’Dowd, Jacqueline, Nolan, Anna L, Cawthorne, Michael A

“…Activation of the hexosamine biosynthesis pathway leads to insulin resistance in muscle and adipose tissue. In these tissues leptin gene expression is…”
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The effects of rexinoids and rosiglitazone on body weight and uncoupling protein isoform expression in the Zucker fa/fa rat by Emilsson, Valur, O'Dowd, Jacqueline, Wang, Steven, Liu, Yong-Ling, Sennitt, Matthew, Heyman, Richard, Cawthorne, Michael A.

“…Agonists for the retinoid X receptor (RXR), the rexinoids, and the peroxisome proliferator-activated receptor gamma (PPAR γ), the thiazolidinediones, are…”
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Interleukin-1beta activates a short STAT-3 isoform in clonal insulin-secreting cells by Morton, N M, de Groot, R P, Cawthorne, M A, Emilsson, V

“…Interleukin-1beta (IL-1beta) is a potent inflammatory cytokine involved in type 1 diabetes and acts through defined IL-1beta signaling pathways. In the present…”
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