Search Results - "Emiliano C. C. Pozzi"
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Therapeutic efficacy of boron neutron capture therapy mediated by boron-rich liposomes for oral cancer in the hamster cheek pouch model
Published in Proceedings of the National Academy of Sciences - PNAS (11-11-2014)“…The application of boron neutron capture therapy (BNCT) mediated by liposomes containing ¹⁰B-enriched polyhedral borane and carborane derivatives for the…”
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Cobaltabis(Dicarbollide) [ o -COSAN] - for Boron Neutron Capture Therapy of Head and Neck Cancer: Biodistribution and Irradiation Studies in an Experimental Oral Cancer Model
Published in Pharmaceuticals (Basel, Switzerland) (01-10-2024)“…Boron neutron capture therapy (BNCT) is a tumor-selective particle radiotherapy that combines preferential boron accumulation in tumors and neutron…”
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Enhancement in the Therapeutic Efficacy of In Vivo BNCT Mediated by GB-10 with Electroporation in a Model of Oral Cancer
Published in Cells (Basel, Switzerland) (25-04-2023)“…Boron neutron capture therapy (BNCT) combines preferential tumor uptake of B compounds and neutron irradiation. Electroporation induces an increase in the…”
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Therapeutic Efficacy, Radiotoxicity and Abscopal Effect of BNCT at the RA-3 Nuclear Reactor Employing Oligo-Fucoidan and Glutamine as Adjuvants in an Ectopic Colon Cancer Model in Rats
Published in Life (Basel, Switzerland) (01-07-2023)“…Boron neutron capture therapy (BNCT) is based on the preferential uptake of B compounds by tumors, followed by neutron irradiation. The aim of this study was…”
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Abscopal effect of boron neutron capture therapy (BNCT): proof of principle in an experimental model of colon cancer
Published in Radiation and environmental biophysics (01-11-2017)“…The aim of the present study was to evaluate, for the first time, the abscopal effect of boron neutron capture therapy (BNCT). Twenty-six BDIX rats were…”
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“Sequential” Boron Neutron Capture Therapy (BNCT): A Novel Approach to BNCT for the Treatment of Oral Cancer in the Hamster Cheek Pouch Model
Published in Radiation research (01-04-2011)“…In the present study the therapeutic effect and potential toxicity of the novel “Sequential” boron neutron capture therapy (Seq-BNCT) for the treatment of oral…”
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Boron neutron capture synovectomy (BNCS) as a potential therapy for rheumatoid arthritis: radiobiological studies at RA-1 Nuclear Reactor in a model of antigen-induced arthritis in rabbits
Published in Radiation and environmental biophysics (01-11-2016)“…Rheumatoid arthritis is a chronic autoimmune pathology characterized by the proliferation and inflammation of the synovium. Boron neutron capture synovectomy…”
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Boron neutron capture therapy (BNCT) translational studies in the hamster cheek pouch model of oral cancer at the new “B2” configuration of the RA-6 nuclear reactor
Published in Radiation and environmental biophysics (01-11-2017)“…Boron neutron capture therapy (BNCT) is based on selective accumulation of B-10 carriers in tumor followed by neutron irradiation. We demonstrated, in 2001,…”
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Boron neutron capture therapy (BNCT) for the treatment of liver metastases: biodistribution studies of boron compounds in an experimental model
Published in Radiation and environmental biophysics (01-03-2011)“…We previously demonstrated the therapeutic efficacy of different boron neutron capture therapy (BNCT) protocols in an experimental model of oral cancer. BNCT…”
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Boron Neutron Capture Therapy (BNCT) Mediated by Maleimide-Functionalized Closo-Dodecaborate Albumin Conjugates (MID:BSA) for Oral Cancer: Biodistribution Studies and In Vivo BNCT in the Hamster Cheek Pouch Oral Cancer Model
Published in Life (Basel, Switzerland) (20-07-2022)“…Background: BNCT (Boron Neutron Capture Therapy) is a tumor-selective particle radiotherapy that combines preferential boron accumulation in tumors and neutron…”
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Boron neutron capture therapy (BNCT) for liver metastasis: therapeutic efficacy in an experimental model
Published in Radiation and environmental biophysics (01-08-2012)“…Boron neutron capture therapy (BNCT) was proposed for untreatable colorectal liver metastases. The present study evaluates tumor control and potential…”
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Blood Vessel Normalization in the Hamster Oral Cancer Model for Experimental Cancer Therapy Studies
Published in Anticancer research (01-07-2012)“…Normalization of tumor blood vessels improves drug and oxygen delivery to cancer cells. The aim of this study was to develop a technique to normalize blood…”
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Biodistribution of sodium borocaptate (BSH) for boron neutron capture therapy (BNCT) in an oral cancer model
Published in Radiation and environmental biophysics (01-08-2013)“…Boron neutron capture therapy (BNCT) is based on selective accumulation of 10 B carriers in tumor followed by neutron irradiation. We previously proved the…”
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Boron delivery with liposomes for boron neutron capture therapy (BNCT): biodistribution studies in an experimental model of oral cancer demonstrating therapeutic potential
Published in Radiation and environmental biophysics (01-05-2012)“…Boron neutron capture therapy (BNCT) combines selective accumulation of 10 B carriers in tumor tissue with subsequent neutron irradiation. We previously…”
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Boron Neutron Capture Therapy (BNCT) in an oral precancer model: Therapeutic benefits and potential toxicity of a double application of BNCT with a six-week interval
Published in Oral oncology (01-11-2011)“…Summary Given the clinical relevance of locoregional recurrences in head and neck cancer, we developed a novel experimental model of premalignant tissue in the…”
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Boron neutron capture therapy (BNCT) for liver metastasis in an experimental model: dose–response at five-week follow-up based on retrospective dose assessment in individual rats
Published in Radiation and environmental biophysics (01-11-2013)“…Boron neutron capture therapy (BNCT) was proposed for untreatable colorectal liver metastases. Employing an experimental model of liver metastases in rats, we…”
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Tumor Blood Vessel “Normalization” Improves the Therapeutic Efficacy of Boron Neutron Capture Therapy (BNCT) in Experimental Oral Cancer
Published in Radiation research (01-01-2012)“…We previously demonstrated the efficacy of BNCT mediated by boronophenylalanine (BPA) to treat tumors in a hamster cheek pouch model of oral cancer with no…”
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Intercalibration of physical neutron dosimetry for the RA-3 and MURR thermal neutron sources for BNCT small-animal research
Published in Applied radiation and isotopes (01-12-2011)“…New thermal neutron irradiation facilities to perform cell and small-animal irradiations for Boron Neutron Capture Therapy research have been installed at the…”
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Evaluation of local, regional and abscopal effects of Boron Neutron Capture Therapy (BNCT) combined with immunotherapy in an ectopic colon cancer model
Published in British journal of radiology (01-12-2021)“…The aim of the present study was to evaluate the local and regional therapeutic efficacy and abscopal effect of BNCT mediated by boronophenyl-alanine, combined…”
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Optimization of the classical oral cancerization protocol in hamster to study oral cancer therapy
Published in Oral diseases (01-09-2020)“…Objective(s) The hamster carcinogenesis model recapitulates oral oncogenesis. Dimethylbenz[a]anthracene (DMBA) cancerization induces early severe mucositis,…”
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