Search Results - "Emilia Maellaro"

Autophagy is upregulated in ovarian endometriosis: a possible interplay with p53 and heme oxygenase-1 by Allavena, Giulia, M.S, Carrarelli, Patrizia, Ph.D, Del Bello, Barbara, Ph.D, Luisi, Stefano, M.D., Ph.D, Petraglia, Felice, M.D, Maellaro, Emilia, Ph.D

“…Objective To evaluate the occurrence of the autophagic process in ovarian endometriomas compared with eutopic endometrium of affected women and with normal…”
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The autophagy inducer trehalose stimulates macropinocytosis in NF1-deficient glioblastoma cells by Del Bello, Barbara, Gamberucci, Alessandra, Marcolongo, Paola, Maellaro, Emilia

“…Background Glioblastoma is a highly aggressive brain tumor. A big effort is required to find novel molecules which can cross the blood–brain barrier and…”
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Cisplatin-induced apoptosis inhibits autophagy, which acts as a pro-survival mechanism in human melanoma cells by Del Bello, Barbara, Toscano, Marzia, Moretti, Daniele, Maellaro, Emilia

“…The interplay between a non-lethal autophagic response and apoptotic cell death is still a matter of debate in cancer cell biology. In the present study…”
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Regulation of autophagy in the uterus: from physiological processes to endometriosis and uterine fibroids by Marcolongo, Paola, Maellaro, Emilia, Luisi, Stefano

“…Endometriosis and uterine fibroids are 2 common gynecological disorders. Their pathophysiology remains unclear, although several different risk factors have…”
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Autoantibodies against the autophagic protein microtubule-associated light-chain 3 (LC3): Immunocharacterization of an atypical ANA pattern by Maellaro, Emilia, Terzuoli, Lucia, Bacarelli, Maria Romana, Del Bello, Barbara, Bizzaro, Nicola, Porcelli, Brunetta

“…Autoantibodies to nuclear and cytoplasmic antigens are commonly detected by indirect immunofluorescence (IIF) on HEp-2 cells, and three major staining patterns…”
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Calpain-3 impairs cell proliferation and stimulates oxidative stress-mediated cell death in melanoma cells by Moretti, Daniele, Del Bello, Barbara, Allavena, Giulia, Corti, Alessandro, Signorini, Cinzia, Maellaro, Emilia

“…Calpain-3 is an intracellular cysteine protease, belonging to Calpain superfamily and predominantly expressed in skeletal muscle. In human melanoma cell lines…”
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Hydrogel containing l-valine residues as a platform for cisplatin chemotherapy by Casolaro, Mario, Barbara, Del Bello, Emilia, Maellaro

“…[Display omitted] ► Hydrogels with l-valine residues were synthesized at low degree of crosslinking and loaded with cisplatin with a well-defined…”
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Correction: Cisplatin-Induced Apoptosis Inhibits Autophagy, Which Acts as a Pro-Survival Mechanism in Human Melanoma Cells by Del Bello, Barbara, Toscano, Marzia, Moretti, Daniele, Maellaro, Emilia

“…The correct affiliation is: 1 Department of Pathophysiology, Experimental Medicine and Public Health, University of Siena, Siena, Italy, and Istituto Toscano…”
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Antitubulinic effect of New Fluorazone Derivatives on Melanoma Cells by Sticozzi, Claudia, Aiello, Francesca, Andreasi, Rita Bassi, Muresan, Ximena Maria, Belmonte, Giuseppe, Cervellati, Franco, Maellaro, Emilia, Maioli, Emanuela, Valacchi, Giuseppe

“…Microtubules are composed by α- and β-tubulin polypeptides. α-tubulin undergoes a reversible posttranslational modification whereby the C-terminal tyrosine…”
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The dark side of gamma-glutamyltransferase (GGT): Pathogenic effects of an ‘antioxidant’ enzyme by Corti, Alessandro, Belcastro, Eugenia, Dominici, Silvia, Maellaro, Emilia, Pompella, Alfonso

“…Having long been regarded as just a member in the cellular antioxidant systems, as well as a clinical biomarker of hepatobiliary diseases and alcohol abuse,…”
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Loss of MYC Confers Resistance to Doxorubicin-induced Apoptosis by Preventing the Activation of Multiple Serine Protease- and Caspase-mediated Pathways by Grassilli, Emanuela, Ballabeni, Andrea, Maellaro, Emilia, Del Bello, Barbara, Helin, Kristian

“…c-Myc plays an essential role in proliferation, differentiation, and apoptosis. Because of its relevance to cancer, most studies have focused on the cellular…”
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Cleavage of Bcl-2 in oxidant- and cisplatin-induced apoptosis of human melanoma cells by DEL BELLO, Barbara, VALENTINI, Marta A, ZUNINO, Franco, COMPORTI, Mario, MAELLARO, Emilia

“…Although the anti-apoptotic effect of Bcl-2 is well established, the role of Bcl-2 in tumour response to therapy and drug resistance is still unclear. The…”
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Calpains and cancer: Friends or enemies? by Moretti, Daniele, Del Bello, Barbara, Allavena, Giulia, Maellaro, Emilia

“…•Calpains proteolyze many substrates, degrading them or modulating their function.•Human calpains comprise ubiquitous and tissue-specific isoforms.•Calpains…”
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Erythrocyte caspase-3 activation and oxidative imbalance in erythrocytes and in plasma of type 2 diabetic patients by Maellaro, Emilia, Leoncini, Silvia, Moretti, Daniele, Del Bello, Barbara, Tanganelli, Italo, De Felice, Claudio, Ciccoli, Lucia

“…An increased oxidative stress and a decreased life span of erythrocytes (RBCs) are reported in patients with diabetes. Aim of this study was to assess in RBCs…”
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Autophagy up-regulation by ulipristal acetate as a novel target mechanism in the treatment of uterine leiomyoma: an in vitro study by Del Bello, Barbara, Marcolongo, Paola, Ciarmela, Pasquapina, Sorbi, Flavia, Petraglia, Felice, Luisi, Stefano, Maellaro, Emilia

“…To assess the effect of ulipristal acetate (UPA) on the autophagic process of uterine leiomyoma cells. In vitro study in primary cultures of leiomyoma and…”
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Trehalose inhibits cell proliferation and amplifies long‐term temozolomide‐ and radiation‐induced cytotoxicity in melanoma cells: A role for autophagy and premature senescence by Allavena, Giulia, Del Bello, Barbara, Tini, Paolo, Volpi, Nila, Valacchi, Giuseppe, Miracco, Clelia, Pirtoli, Luigi, Maellaro, Emilia

“…Cutaneous melanomas frequently metastasize to the brain, with temozolomide (TMZ) plus radiotherapy (RT) offering little control of these lesions. We tested…”
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Glutathione depletion, lipid peroxidation, and the antecedents of ferroptosis: What about cellular calcium ? by Pompella, Alfonso, Maellaro, Emilia, Benedetti, Angiolo, Casini, Alessandro F.

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Autofagia: un processo fisiopatologico di autodigestione cellulare by Maellaro, Emilia

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Long-term doxorubicin release from multiple stimuli-responsive hydrogels based on α-amino-acid residues by Casolaro, Mario, Casolaro, Ilaria, Bottari, Severino, Del Bello, Barbara, Maellaro, Emilia, Demadis, Konstantinos D.

“…Cumulative doxorubicin release (%) from DOXO-loaded magnetic-hydrogels based on α-aminoacid residues (l-phenylalanine and l-valine) under different…”
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Suppressed translation and ULK1 degradation as potential mechanisms of autophagy limitation under prolonged starvation by Allavena, Giulia, Boyd, Caroline, Oo, Kyaw Soe, Maellaro, Emilia, Zhivotovsky, Boris, Kaminskyy, Vitaliy O.

“…Macroautophagy/autophagy is a well-organized process of intracellular degradation, which is rapidly activated under starvation conditions. Recent data…”
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