Search Results - "Emili, Luca"
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Scientific and regulatory evaluation of mechanistic in silico drug and disease models in drug development: Building model credibility
Published in CPT: pharmacometrics and systems pharmacology (01-08-2021)“…The value of in silico methods in drug development and evaluation has been demonstrated repeatedly and convincingly. While their benefits are now unanimously…”
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What public health challenges and unmet medical needs would benefit from interdisciplinary collaboration in the EU? A survey and multi-stakeholder debate
Published in Frontiers in public health (22-07-2024)“…In the past decade, significant European calls for research proposals have supported translational collaborative research on non-communicable and infectious…”
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Accelerating Digitalization in Healthcare with the InSilicoTrials Cloud-Based Platform: Four Use Cases
Published in Annals of biomedical engineering (01-01-2023)“…The use of in silico trials is expected to play an increasingly important role in the development and regulatory evaluation of new medical products. Among the…”
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Possible Contexts of Use for In Silico Trials Methodologies: A Consensus-Based Review
Published in IEEE journal of biomedical and health informatics (01-10-2021)“…The term " In Silico Trial" indicates the use of computer modelling and simulation to evaluate the safety and efficacy of a medical product, whether a drug, a…”
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Advancing In Silico Clinical Trials for Regulatory Adoption and Innovation
Published in IEEE journal of biomedical and health informatics (08-11-2024)“…The evolution of information and communication technologies has affected all fields of science, including health sciences. However, the rate of technological…”
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FARMAPRICE: A Pharmacogenetic Clinical Decision Support System for Precise and Cost-Effective Therapy
Published in Genes (04-04-2019)“…Pharmacogenetic (PGx) guidelines for the precise dosing and selection of drugs remain poorly implemented in current clinical practice. Among the barriers to…”
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Possible Contexts of Use for In Silico trials methodologies: a consensus-based review
Published 28-03-2021“…The term "In Silico Trial" indicates the use of computer modelling and simulation to evaluate the safety and efficacy of a medical product, whether a drug, a…”
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