Search Results - "Emig, Ramona"

Passive myocardial mechanical properties: meaning, measurement, models by Emig, Ramona, Zgierski-Johnston, Callum M., Timmermann, Viviane, Taberner, Andrew J., Nash, Martyn P., Kohl, Peter, Peyronnet, Rémi

“…Passive mechanical tissue properties are major determinants of myocardial contraction and relaxation and, thus, shape cardiac function. Tightly regulated,…”
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Piezo1 Channels Contribute to the Regulation of Human Atrial Fibroblast Mechanical Properties and Matrix Stiffness Sensing by Emig, Ramona, Knodt, Wiebke, Krussig, Mario J, Zgierski-Johnston, Callum M, Gorka, Oliver, Groß, Olaf, Kohl, Peter, Ravens, Ursula, Peyronnet, Rémi

“…The mechanical environment of cardiac cells changes continuously and undergoes major alterations during diseases. Most cardiac diseases, including atrial…”
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Repurposing mesalazine against cardiac fibrosis in vitro by Hoffmann, Maximilian, Kant, Theresa A., Emig, Ramona, Rausch, Johanna S. E., Newe, Manja, Schubert, Mario, Künzel, Karolina, Winter, Luise, Klapproth, Erik, Peyronnet, Rémi, Ravens, Ursula, El-Armouche, Ali, Künzel, Stephan R.

“…Cardiovascular diseases are exacerbated and driven by cardiac fibrosis. TGFβ induces fibroblast activation and differentiation into myofibroblasts that secrete…”
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Human Atrial Fibroblast Adaptation to Heterogeneities in Substrate Stiffness by Emig, Ramona, Zgierski-Johnston, Callum M, Beyersdorf, Friedhelm, Rylski, Bartosz, Ravens, Ursula, Weber, Wilfried, Kohl, Peter, Hörner, Maximilian, Peyronnet, Rémi

“…Fibrosis is associated with aging and many cardiac pathologies. It is characterized both by myofibroblast differentiation and by excessive accumulation of…”
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Divergent and Compensatory Effects of BMP2 and BMP4 on the VSMC Phenotype and BMP4's Role in Thoracic Aortic Aneurysm Development by Klessinger, Daniel, Mamazhakypov, Argen, Glaeser, Sophie, Emig, Ramona, Peyronnet, Remi, Meier, Lena, Proelss, Kora, Marenne, Katia, Smolka, Christian, Grundmann, Sebastian, Pankratz, Franziska, Esser, Philipp R, Moser, Martin, Zhou, Qian, Esser, Jennifer S

“…Vascular smooth muscle cells (VSMCs) play a key role in aortic aneurysm formation. Bone morphogenetic proteins (BMPs) have been implicated as important…”
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Modeling atrial fibrosis in vitro—Generation and characterization of a novel human atrial fibroblast cell line by Künzel, Stephan R., Rausch, Johanna S. E., Schäffer, Charlotte, Hoffmann, Maximilian, Künzel, Karolina, Klapproth, Erik, Kant, Theresa, Herzog, Natalie, Küpper, Jan‐Heiner, Lorenz, Kristina, Dudek, Svenja, Emig, Ramona, Ravens, Ursula, Rog‐Zielinska, Eva A., Peyronnet, Rémi, El‐Armouche, Ali

“…Atrial fibrillation (AF) is regularly accompanied by cardiac fibrosis and concomitant heart failure. Due to the heterogeneous nature and complexity of…”
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Myocardial Inflammation in Heart Failure With Reduced and Preserved Ejection Fraction by Alcaide, Pilar, Kallikourdis, Marinos, Emig, Ramona, Prabhu, Sumanth D

“…Heart failure (HF) is characterized by a progressive decline in cardiac function and represents one of the largest health burdens worldwide. Clinically, 2…”
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Cardiac mechano‐electric crosstalk: multi‐scale observations, computational integration, and clinical implications by Emig, Ramona, MacDonald, Eilidh A., Quinn, T. Alexander

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Abstract We075: Stimulator of Interferon Genes (STING) Regulates T Cell Fate in Cardiometabolic Heart Failure with Preserved Ejection Fraction (HFpEF) by Smolgovsky, Sasha, Bayer, Abraham, Emig, Ramona, Magri, Zoie, aronovitz, mark, kaur, Kuljeet, Poltorak, Alexander, Blanton, Robert, Alcaide, Pilar

“…Abstract only Introduction: Combined obesity and hypertension alter the endoplasmic reticulum (ER) stress response by downregulating X-box binding protein 1 (…”
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Synthesis of a Light-Controlled Phytochrome-Based Extracellular Matrix with Reversibly Adjustable Mechanical Properties by Hörner, Maximilian, Hoess, Philipp, Emig, Ramona, Rebmann, Balder, Weber, Wilfried

“…Synthetic extracellular matrices with reversibly adjustable mechanical properties are essential for the investigation of how cells respond to dynamic…”
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Simultaneous assessment of radial and axial myocyte mechanics by combining atomic force microscopy and carbon fibre techniques by Peyronnet, Rémi, Desai, Aesha, Edelmann, Jan-Christoph, Cameron, Breanne A, Emig, Ramona, Kohl, Peter, Dean, Delphine

“…Cardiomyocytes sense and shape their mechanical environment, contributing to its dynamics by their passive and active mechanical properties. While axial forces…”
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Piezo1 and BKCa channels in human atrial fibroblasts: Interplay and remodelling in atrial fibrillation by Jakob, Dorothee, Klesen, Alexander, Allegrini, Benoit, Darkow, Elisa, Aria, Diana, Emig, Ramona, Chica, Ana Simon, Rog-Zielinska, Eva A., Guth, Tim, Beyersdorf, Friedhelm, Kari, Fabian A., Proksch, Susanne, Hatem, Stéphane N., Karck, Matthias, Künzel, Stephan R., Guizouarn, Hélène, Schmidt, Constanze, Kohl, Peter, Ravens, Ursula, Peyronnet, Rémi

“…Atrial Fibrillation (AF) is an arrhythmia of increasing prevalence in the aging populations of developed countries. One of the important indicators of AF is…”
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Piezo1 stretch‐activated channel activity differs between murine bone marrow‐derived and cardiac tissue‐resident macrophages by Simon‐Chica, Ana, Klesen, Alexander, Emig, Ramona, Chan, Andy, Greiner, Joachim, Grün, Dominic, Lother, Achim, Hilgendorf, Ingo, Rog‐Zielinska, Eva A., Ravens, Ursula, Kohl, Peter, Schneider‐Warme, Franziska, Peyronnet, Rémi

“…Macrophages (MΦ) play pivotal roles in tissue homeostasis and repair. Their mechanical environment has been identified as a key modulator of various cell…”
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Cardiac fibroblasts: Active players in (atrial) electrophysiology? by Klesen, Alexander, Jakob, Dorothee, Emig, Ramona, Kohl, Peter, Ravens, Ursula, Peyronnet, Rémi

“…Fibrotic areas in cardiac muscle—be it in ventricular or atrial tissue—are considered as obstacles for conduction of the excitatory wave and can therefore…”
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Benchmarking of Cph1 Mutants and Dr BphP for Light‐Responsive Phytochrome‐Based Hydrogels with Reversibly Adjustable Mechanical Properties by Emig, Ramona, Hoess, Philipp, Cai, Hanyang, Kohl, Peter, Peyronnet, Rémi, Weber, Wilfried, Hörner, Maximilian

“…Abstract In the rapidly expanding field of molecular optogenetics, the performance of the engineered systems relies on the switching properties of the…”
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Benchmarking of Cph1 Mutants and DrBphP for Light‐Responsive Phytochrome‐Based Hydrogels with Reversibly Adjustable Mechanical Properties by Emig, Ramona, Hoess, Philipp, Cai, Hanyang, Kohl, Peter, Peyronnet, Rémi, Weber, Wilfried, Hörner, Maximilian

“…In the rapidly expanding field of molecular optogenetics, the performance of the engineered systems relies on the switching properties of the underlying…”
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Multiplexed antibody detection from blood sera by immobilization of in vitro expressed antigens and label-free readout via imaging reflectometric interferometry (iRIf) by Bender, Julian, Bognar, Sabine, Camagna, Maurizio, Donauer, Julia A.M., Eble, Julian W., Emig, Ramona, Fischer, Sabrina, Jesser, Rabea, Keilholz, Luisa, Kokotek, Daniel M.U., Neumann, Julika, Nicklaus, Simon, Oude Weernink, Ricardo R.Q.P.T., Stühn, Lara G., Wössner, Nathalie, Krämer, Stefan D., Schwenk, Philipp, Gensch, Nicole, Roth, Günter, Ulbrich, Maximilian H.

“…The detection of antibodies from blood sera is crucial for diagnostic purposes. Miniaturized protein assays in combination with microfluidic setups hold great…”
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Piezo1 and BK Ca channels in human atrial fibroblasts: Interplay and remodelling in atrial fibrillation by Jakob, Dorothee, Klesen, Alexander, Allegrini, Benoit, Darkow, Elisa, Aria, Diana, Emig, Ramona, Chica, Ana Simon, Rog-Zielinska, Eva A, Guth, Tim, Beyersdorf, Friedhelm, Kari, Fabian A, Proksch, Susanne, Hatem, Stéphane N, Karck, Matthias, Künzel, Stephan R, Guizouarn, Hélène, Schmidt, Constanze, Kohl, Peter, Ravens, Ursula, Peyronnet, Rémi

“…Atrial Fibrillation (AF) is an arrhythmia of increasing prevalence in the aging populations of developed countries. One of the important indicators of AF is…”
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Impact of Mechanically-Induced Fibrosis on Atrial Electromechanical Function by Schiatti, Teresa, Casini, Marilu, Hutschalik, Thomas, Koch, Manuel, Emig, Ramona, Peyronnet, Remi, Ravens, Ursula

“…Atrial fibrillation is accompanied by remodelling processes on the structural, electrophysiological, and contractile levels. These alterations result at least…”
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