Search Results - "Emi, Y"
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Multifunctional bioscaffolds for 3D culture of melanoma cells reveal increased MMP activity and migration with BRAF kinase inhibition
Published in Proceedings of the National Academy of Sciences - PNAS (28-04-2015)“…Matrix metalloproteinases (MMPs) are important for many different types of cancer-related processes, including metastasis. Understanding the functional impact…”
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Modulation of matrix elasticity with PEG hydrogels to study melanoma drug responsiveness
Published in Biomaterials (01-05-2014)“…Abstract Metastatic melanoma is highly resistant to drug treatment, and the underlying mechanisms of this resistance remain unclear. Increased tissue stiffness…”
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PEG-peptide hydrogels reveal differential effects of matrix microenvironmental cues on melanoma drug sensitivity
Published in Integrative biology (Cambridge) (01-01-2017)“…Metastatic melanoma is highly drug resistant, though the exact mechanisms of this resistance are not completely understood. One method to study melanoma drug…”
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A randomized phase III trial comparing S-1 versus UFT as adjuvant chemotherapy for stage II/III rectal cancer (JFMC35-C1: ACTS-RC)
Published in Annals of oncology (01-07-2016)“…Preventing distant recurrence and achieving local control are important challenges in rectal cancer treatment, and use of adjuvant chemotherapy has been…”
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Low-Energy Vibrations of the Group 10 Metal Monocarbonyl MCO (M = Ni, Pd, and Pt): Rotational Spectroscopy and Force Field Analysis
Published in The journal of physical chemistry. A, Molecules, spectroscopy, kinetics, environment, & general theory (17-03-2011)“…The rotational spectra of NiCO and PdCO in the ground and ν2 excited vibrational states were observed by employing a source-modulated microwave spectrometer…”
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Synthesis of Microgel Sensors for Spatial and Temporal Monitoring of Protease Activity
Published in ACS biomaterials science & engineering (12-02-2018)“…Proteases are involved in almost every important cellular activity, from embryonic morphogenesis to apoptosis. To study protease activity in situ, hydrogels…”
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Detection of Free Monomeric Silver(I) and Gold(I) Cyanides, AgCN and AuCN: Microwave Spectra and Molecular Structure
Published in Journal of the American Chemical Society (26-08-2009)“…The chemistry of the group 11 metal cyanide system has been of considerable interest because of the commercial importance of some of the complexes formed in…”
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A quantitative comparison of human HT-1080 fibrosarcoma cells and primary human dermal fibroblasts identifies a 3D migration mechanism with properties unique to the transformed phenotype
Published in PloS one (03-12-2013)“…Here, we describe an engineering approach to quantitatively compare migration, morphologies, and adhesion for tumorigenic human fibrosarcoma cells (HT-1080s)…”
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Splenic volume may be a useful indicator of the protective effect of bevacizumab against oxaliplatin-induced hepatic sinusoidal obstruction syndrome
Published in European journal of surgical oncology (01-05-2014)“…Abstract Aims The aim of this study was to investigate the relationship between the use of bevacizumab (Bmab) in addition to oxaliplatin (OX), the development…”
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Evaluation of resectability after neoadjuvant chemotherapy for primary non-resectable colorectal liver metastases: A multicenter study
Published in European journal of surgical oncology (01-02-2016)“…Abstract Background/Aim The Kyushu Study Group of Clinical Cancer (KSCC) previously reported the safety and efficacy of neoadjuvant chemotherapy with…”
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Effects of an elemental diet to reduce adverse events in patients with esophageal cancer receiving docetaxel/cisplatin/5-fluorouracil: a phase III randomized controlled trial—EPOC 2 (JFMC49-1601-C5)
Published in ESMO open (01-10-2021)“…Oral mucositis (OM) is an unpleasant adverse event in patients receiving chemotherapy. A prospective feasibility study showed that elemental diet (ED), an oral…”
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2137 Comparison of two Phase II trials of mFOLFOX6 plus bevacizumab (KSCC0802) and SOX (S-1 and oxaliplatin) plus cetuximab (KSCC1002): First line chemotherapy in colorectal cancer patients with initially unresectable or not optimally resectable liver only metastases
Published in European journal of cancer (1990) (01-09-2015)Get full text
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1529-P: Hypothalamic FGF1 Regulates Systemic Glucose and Energy Homeostasis
Published in Diabetes (New York, N.Y.) (20-06-2023)“…Systemic glucose and energy homeostasis is maintained by interorgan communication networks and the hypothalamus plays a key part in this process. Many research…”
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Transcriptional Enhancement of UDP-Glucuronosyltransferase Form 1A2 (UGT1A2) by Nuclear Factor I-A (NFI-A) in Rat Hepatocytes
Published in Journal of biochemistry (Tokyo) (01-09-2005)“…In cultured primary hepatocytes UDP-glucuronosyltransferase form 1A2 (UGT1A2) mRNA level is 80 times higher than that found in rat liver. We previously…”
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Analysis of an even-skipped rescue transgene reveals both composite and discrete neuronal and early blastoderm enhancers, and multi-stripe positioning by gap gene repressor gradients
Published in Development (Cambridge) (01-06-1999)“…The entire functional even-skipped locus of Drosophila melanogaster is contained within a 16 kilobase region. As a transgene, this region is capable of…”
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