Search Results - "Emi, Kyoichi"
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Cbln1 Is a Ligand for an Orphan Glutamate Receptor δ2, a Bidirectional Synapse Organizer
Published in Science (American Association for the Advancement of Science) (16-04-2010)“…Cbln1, secreted from cerebellar granule cells, and the orphan glutamate receptor δ2 (GluD2), expressed by Purkinje cells, are essential for synapse integrity…”
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Activity-Dependent Repression of Cbln1 Expression: Mechanism for Developmental and Homeostatic Regulation of Synapses in the Cerebellum
Published in The Journal of neuroscience (29-04-2009)“…Cbln1, which belongs to the C1q/tumor necrosis factor superfamily, is released from cerebellar granule cells and plays a crucial role in forming and…”
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Differential Regulation of Synaptic Plasticity and Cerebellar Motor Learning by the C-Terminal PDZ-Binding Motif of GluRδ2
Published in The Journal of neuroscience (06-02-2008)“…The δ2 glutamate receptor (GluRδ2) is predominantly expressed in Purkinje cells and plays crucial roles in cerebellar functions: GluR δ 2 −/− mice display…”
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4
Reevaluation of the role of parallel fiber synapses in delay eyeblink conditioning in mice using Cbln1 as a tool
Published in Frontiers in neural circuits (15-11-2013)“…The delay eyeblink conditioning (EBC) is a cerebellum-dependent type of associative motor learning. However, the exact roles played by the various cerebellar…”
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5
A New Rapid Protocol for Eyeblink Conditioning to Assess Cerebellar Motor Learning
Published in Neurochemical research (01-07-2011)“…Mice with spontaneous and induced mutations causing cerebellar phenotypes have provided key insights into how motor-related memories are stored in cerebellar…”
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D -Serine regulates cerebellar LTD and motor coordination through the δ2 glutamate receptor
Published in Nature neuroscience (01-05-2011)“…This study demonstrates that D -serine released from Bergmann glia can act as a ligand for Δ2 glutamate receptor to regulate long-term depression at parallel…”
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D-Serine regulates cerebellar LTD and motor coordination through the delta 2 glutamate receptor
Published in Nature neuroscience (01-05-2011)“…D-Serine (D-Ser) is an endogenous co-agonist for NMDA receptors and regulates neurotransmission and synaptic plasticity in the forebrain. D-Ser is also found…”
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The N-Terminal Domain of GluD2 (GluR{delta}2) Recruits Presynaptic Terminals and Regulates Synaptogenesis in the Cerebellum In Vivo
Published in The Journal of neuroscience (06-05-2009)“…The delta2 glutamate receptor (GluRdelta2; GluD2), which is predominantly expressed on postsynaptic sites at parallel fiber (PF)-Purkinje cell synapses in the…”
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10
Differential Regulation of Synaptic Plasticity and Cerebellar Motor Learning by the C-Terminal PDZ-Binding Motif of GluR delta 2
Published in The Journal of neuroscience (06-02-2008)“…The delta 2 glutamate receptor (GluR delta 2) is predominantly expressed in Purkinje cells and plays crucial roles in cerebellar functions: GluR delta 2…”
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Cbln1 Regulates Rapid Formation and Maintenance of Excitatory Synapses in Mature Cerebellar Purkinje Cells In Vitro and In Vivo
Published in The Journal of neuroscience (04-06-2008)“…Although many synapse-organizing molecules have been identified in vitro, their functions in mature neurons in vivo have been mostly unexplored. Cbln1, which…”
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12
D-Serine regulates cerebellar LTD and motor coordination through the [delta]2 glutamate receptor
Published in Nature neuroscience (01-05-2011)“…D-serine (D-Ser) is an endogenous co-agonist for NMDA receptors and regulates neurotransmission and synaptic plasticity in the forebrain. D-Ser is also found…”
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13
Cbln1 Is a Ligand for an Orphan Glutamate Receptor [delta]2, a Bidirectional Synapse Organizer
Published in Science (American Association for the Advancement of Science) (16-04-2010)“…The glutamate receptor δ2 (GluD2), another member of the ionotropic glutamate receptor family, has long been considered to be an orphan receptor because there…”
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14
Differential regulation of synaptic plasticity and cerebellar motor learning by the C-terminal PDZ-binding motif of GluRdelta2
Published in The Journal of neuroscience (06-02-2008)“…The delta2 glutamate receptor (GluRdelta2) is predominantly expressed in Purkinje cells and plays crucial roles in cerebellar functions: GluRdelta2-/- mice…”
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15
Impaired delay, but normal trace classical eyeblink conditioning in the Cbln1 mutant mice
Published in Neuroscience research (2007)Get full text
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16
Cbln1 is a ligand for an orphan glutamate receptor delta2, a bidirectional synapse organizer
Published in Science (American Association for the Advancement of Science) (16-04-2010)“…Cbln1, secreted from cerebellar granule cells, and the orphan glutamate receptor delta2 (GluD2), expressed by Purkinje cells, are essential for synapse…”
Get full text
Journal Article -
17
Differential Regulation of Synaptic Plasticity and Cerebellar Motor Learning by the C-Terminal PDZ-Binding Motif of GluR{delta}2
Published in The Journal of neuroscience (06-02-2008)Get full text
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