Search Results - "Emerson, Mitchell R"

Metabolic pathways as possible therapeutic targets for progressive multiple sclerosis by Heidker, Rebecca M, Emerson, Mitchell R, LeVine, Steven M

“…Unlike relapsing remitting multiple sclerosis, there are very few therapeutic options for patients with progressive forms of multiple sclerosis. While immune…”
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Statistical analysis of data from studies on experimental autoimmune encephalomyelitis by Fleming, Kandace K., Bovaird, James A., Mosier, Michael C., Emerson, Mitchell R., LeVine, Steven M., Marquis, Janet G.

“…Research in multiple sclerosis often employs animal models of the disease, especially experimental autoimmune encephalomyelitis (EAE) in rodents. The…”
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Aspirin and multiple sclerosis by Tsau, Sheila, Emerson, Mitchell R, Lynch, Sharon G, LeVine, Steven M

“…Aspirin is widely used to lessen the risks of cardiovascular events. Some studies suggest that patients with multiple sclerosis have an increased risk for some…”
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Report of the 2017-2018 Student Affairs Standing Committee by Miller, Monica L., Boyer, Casey, Emerson, Mitchell R., Neville, Michael W., Skoy, Elizabeth T., Vogt, Eleanor M., Volino, Lucio, Worrall, Cathy L., Zitko, Kimberly L., Ross, Libby J.

“…The 2017-2018 American Association of Colleges of Pharmacy (AACP) Student Affairs Standing Committee addressed charges related to student wellness and…”
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Intersections of pathways involving biotin and iron relative to therapeutic mechanisms for progressive multiple sclerosis by Heidker, Rebecca M, Emerson, Mitchell R, LeVine, Steven M

“…While there are a variety of therapies for relapsing remitting multiple sclerosis (MS), there is a lack of treatments for progressive MS. An early study…”
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Experimental allergic encephalomyelitis is exacerbated in mice deficient for 12/15-lipoxygenase or 5-lipoxygenase by Emerson, Mitchell R., LeVine, Steven M.

“…12/15-Lipoxygenase (12/15-LO) produces 15-hydroxyeicosatetraenoic acid (15-HETE) and 13-hydroxyoctadecadienoic acid (13-HODE) which are agonists for peroxisome…”
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Enhancing the Ability of Experimental Autoimmune Encephalomyelitis to Serve as a More Rigorous Model of Multiple Sclerosis through Refinement of the Experimental Design by Emerson, Mitchell R, Gallagher, Ryan J, Marquis, Janet G, LeVine, Steven M

“…Advancing the understanding of the mechanisms involved in the pathogenesis of multiple sclerosis (MS) likely will lead to new and better therapeutics. Although…”
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The central endocrine glands: intertwining physiology and pharmacy by Emerson, Mitchell R

“…The initial courses in didactic pharmacy curriculum are designed to provide core scientific knowledge and develop learning skills that are the basis for highly…”
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Activation of histamine H2 receptors ameliorates experimental allergic encephalomyelitis by Emerson, Mitchell R, Orentas, Diana M, Lynch, Sharon G, LeVine, Steven M

“…Experimental allergic encephalomyelitis (EAE), a model of multiple sclerosis, is an autoimmune, demyelinating disease of the CNS. Pro-inflammatory cytokines…”
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Heme oxygenase-1 and NADPH cytochrome P450 reductase expression in experimental allergic encephalomyelitis: An expanded view of the stress response by EMERSON, Mitchell R, LEVINE, Steven M

“…Oxidative stress is implicated in the pathogenesis of experimental allergic encephalomyelitis (EAE), a model for multiple sclerosis. Heme oxygenase-1 (HO-1) is…”
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Cuprizone and piperonyl butoxide, proposed inhibitors of T-cell function, attenuate experimental allergic encephalomyelitis in SJL mice by Emerson, Mitchell R, Biswas, Sangita, LeVine, Steven M

“…Multiple sclerosis (MS) and its animal model, experimental allergic encephalomyelitis (EAE), are autoimmune demyelinating diseases with autoreactive T-cells…”
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Hypoxia preconditioning attenuates brain edema associated with kainic acid-induced status epilepticus in rats by Emerson, Mitchell R, Nelson, Stanley R, Samson, Fred E, Pazdernik, Thomas L

“…Kainic acid (KA)-induced seizures elicit edema associated with necrosis in susceptible brain regions (e.g., piriform cortex and hippocampal CA 1 and CA 3…”
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Heme Oxygenase‐1 and NADPH Cytochrome P450 Reductase Expression in Experimental Allergic Encephalomyelitis by Emerson, Mitchell R., LeVine, Steven M.

“…: Oxidative stress is implicated in the pathogenesis ofexperimental allergic encephalomyelitis (EAE), a model for multiple sclerosis.Heme oxygenase‐1 (HO‐1) is…”
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Apoferritin attenuates experimental allergic encephalomyelitis in SJL mice by LeVine, Steven M, Maiti, Smarajit, Emerson, Mitchell R, Pedchenko, Tetyana V

“…Ferritin has been shown to attenuate iron-catalyzed oxidative damage in several experimental conditions. Since oxidative damage has been implicated in the…”
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A global hypoxia preconditioning model: neuroprotection against seizure-induced specific gravity changes (edema) and brain damage in rats by Emerson, Mitchell R, Nelson, Stanley R, Samson, Fred E, Pazdernik, Thomas L

“…Hypoxia preconditioning states that a sublethal hypoxia episode will afford neuroprotection against a second challenge in the near future. We describe and…”
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High-Yield Cell and Molecular Biology by Emerson, Mitchell R.

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The Central Endocrine Glands: Intertwining Physiology and Pharmacy by Emerson, Mitchell R

“…The initial courses in didactic pharmacy curriculum are designed to provide core scientific knowledge and develop learning skills that are the basis for highly…”
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The Central Endocrine Glands: Intertwining Physiology and Pharmacy by Emerson, Mitchell R.

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Does Extracellular Ascorbate Promote Oxidative Damage to the Aging Brain? by ROMANAS, MARIA M., EMERSON, MITCHELL R., NELSON, STANLEY R., SAMSON, FRED E., PAZDERNIK, THOMAS L.

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Protocol: A global hypoxia preconditioning model: neuroprotection against seizure-induced specific gravity changes (edema) and brain damage in rats by Emerson, Mitchell R, Nelson, Stanley R, Samson, Fred E, Pazdernik, Thomas L

“…Hypoxia preconditioning states that a sublethal hypoxia episode will afford neuroprotection against a second challenge in the near future. We describe and…”
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