Search Results - "Emerson, Lindsay"

Defects in cell spreading and ERK1/2 activation in fibroblasts with lamin A/C mutations by Emerson, Lindsay J., Holt, Mark R., Wheeler, Matthew A., Wehnert, Manfred, Parsons, Maddy, Ellis, Juliet A.

“…In-frame mutations in nuclear lamin A/C lead to a multitude of tissue-specific degenerative diseases known as the ‘laminopathies’. Previous studies have…”
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The Emery–Dreifuss muscular dystrophy associated‐protein emerin is phosphorylated on serine 49 by protein kinase A by Roberts, Rhys C., Sutherland‐Smith, Andrew J., Wheeler, Matthew A., Norregaard Jensen, Ole, Emerson, Lindsay J., Spiliotis, Ioannis I., Tate, Christopher G., Kendrick‐Jones, John, Ellis, Juliet A.

“…Emerin is a ubiquitously expressed inner nuclear membrane protein of unknown function. Mutations in its gene give rise to X‐linked Emery–Dreifuss muscular…”
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Id Proteins Negatively Regulate Basic Helix-Loop-Helix Transcription Factor Function by Disrupting Subnuclear Compartmentalization by O'Toole, Peter J., Inoue, Toshiaki, Emerson, Lindsay, Morrison, Ian E.G., Mackie, Alan R., Cherry, Richard J., Norton, John D.

“…Id helix-loop-helix (HLH) proteins act as global regulators of metazoan cell fate, cell growth, and differentiation. They heterodimerize with and inhibit the…”
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Distinct functional domains in nesprin-1[alpha] and nesprin-2[beta] bind directly to emerin and both interactions are disrupted in X-linked Emery-Dreifuss muscular dystrophy by Wheeler, Matthew A, Davies, John D, Zhang, Qiuping, Emerson, Lindsay J, Hunt, James, Shanahan, Catherine M, Ellis, Juliet A

“…Emerin and specific isoforms of nesprin-1 and -2 are nuclear membrane proteins which are binding partners in multi-protein complexes spanning the nuclear…”
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Lamins A and C are differentially dysfunctional in autosomal dominant Emery-Dreifuss muscular dystrophy by Motsch, Isabell, Kaluarachchi, Manuja, Emerson, Lindsay J., Brown, Charlotte A., Brown, Susan C., Dabauvalle, Marie-Christine, Ellis, Juliet A.

“…Mutations in the LMNA gene, which encodes nuclear lamins A and C by alternative splicing, can give rise to Emery–Dreifuss muscular dystrophy. The mechanism by…”
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Distinct functional domains in nesprin-1α and nesprin-2β bind directly to emerin and both interactions are disrupted in X-linked Emery–Dreifuss muscular dystrophy by Wheeler, Matthew A., Davies, John D., Zhang, Qiuping, Emerson, Lindsay J., Hunt, James, Shanahan, Catherine M., Ellis, Juliet A.

“…Emerin and specific isoforms of nesprin-1 and -2 are nuclear membrane proteins which are binding partners in multi-protein complexes spanning the nuclear…”
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Distinct functional domains in nesprin-1alpha and nesprin-2beta bind directly to emerin and both interactions are disrupted in X-linked Emery-Dreifuss muscular dystrophy by Wheeler, Matthew A, Davies, John D, Zhang, Qiuping, Emerson, Lindsay J, Hunt, James, Shanahan, Catherine M, Ellis, Juliet A

“…Emerin and specific isoforms of nesprin-1 and -2 are nuclear membrane proteins which are binding partners in multi-protein complexes spanning the nuclear…”
Get full text