Search Results - "Emerging microbes & infections"

Genomic characterization of the 2019 novel human-pathogenic coronavirus isolated from a patient with atypical pneumonia after visiting Wuhan by Chan, Jasper Fuk-Woo, Kok, Kin-Hang, Zhu, Zheng, Chu, Hin, To, Kelvin Kai-Wang, Yuan, Shuofeng, Yuen, Kwok-Yung

“…A mysterious outbreak of atypical pneumonia in late 2019 was traced to a seafood wholesale market in Wuhan of China. Within a few weeks, a novel coronavirus…”
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Molecular and serological investigation of 2019-nCoV infected patients: implication of multiple shedding routes by Zhang, Wei, Du, Rong-Hui, Li, Bei, Zheng, Xiao-Shuang, Yang, Xing-Lou, Hu, Ben, Wang, Yan-Yi, Xiao, Geng-Fu, Yan, Bing, Shi, Zheng-Li, Zhou, Peng

“…In December 2019, a novel coronavirus (2019-nCoV) caused an outbreak in Wuhan, China, and soon spread to other parts of the world. It was believed that…”
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Potent binding of 2019 novel coronavirus spike protein by a SARS coronavirus-specific human monoclonal antibody by Tian, Xiaolong, Li, Cheng, Huang, Ailing, Xia, Shuai, Lu, Sicong, Shi, Zhengli, Lu, Lu, Jiang, Shibo, Yang, Zhenlin, Wu, Yanling, Ying, Tianlei

“…The newly identified 2019 novel coronavirus (2019-nCoV) has caused more than 11,900 laboratory-confirmed human infections, including 259 deaths, posing a…”
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Transcriptomic characteristics of bronchoalveolar lavage fluid and peripheral blood mononuclear cells in COVID-19 patients by Xiong, Yong, Liu, Yuan, Cao, Liu, Wang, Dehe, Guo, Ming, Jiang, Ao, Guo, Dong, Hu, Wenjia, Yang, Jiayi, Tang, Zhidong, Wu, Honglong, Lin, Yongquan, Zhang, Meiyuan, Zhang, Qi, Shi, Mang, Liu, Yingle, Zhou, Yu, Lan, Ke, Chen, Yu

“…Circulating in China and 158 other countries and areas, the ongoing COVID-19 outbreak has caused devastating mortality and posed a great threat to public…”
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Profiling serum cytokines in COVID-19 patients reveals IL-6 and IL-10 are disease severity predictors by Han, Huan, Ma, Qingfeng, Li, Cong, Liu, Rui, Zhao, Li, Wang, Wei, Zhang, Pingan, Liu, Xinghui, Gao, Guosheng, Liu, Fang, Jiang, Yingan, Cheng, Xiaoming, Zhu, Chengliang, Xia, Yuchen

“…Since the outbreak of coronavirus disease 2019 (COVID-19) in Wuhan, China, it has rapidly spread across many other countries. While the majority of patients…”
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Omicron variant showed lower neutralizing sensitivity than other SARS-CoV-2 variants to immune sera elicited by vaccines after boost by Ai, Jingwen, Zhang, Haocheng, Zhang, Yi, Lin, Ke, Zhang, Yanliang, Wu, Jing, Wan, Yanming, Huang, Yanfang, Song, Jieyu, Fu, Zhangfan, Wang, Hongyu, Guo, Jingxin, Jiang, Ning, Fan, Mingxiang, Zhou, Yang, Zhao, Yuanhan, Zhang, Qiran, Liu, Qiang, Lv, Jing, Li, Peiyao, Qiu, Chao, Zhang, Wenhong

“…The emerging new VOC B.1.1.529 (Omicron) variant has raised serious concerns due to multiple mutations, reported significant immune escape, and unprecedented…”
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SARS-CoV-2 Omicron variant shows less efficient replication and fusion activity when compared with Delta variant in TMPRSS2-expressed cells by Zhao, Hanjun, Lu, Lu, Peng, Zheng, Chen, Lin-Lei, Meng, Xinjin, Zhang, Chuyuan, Ip, Jonathan Daniel, Chan, Wan-Mui, Chu, Allen Wing-Ho, Chan, Kwok-Hung, Jin, Dong-Yan, Chen, Honglin, Yuen, Kwok-Yung, To, Kelvin Kai-Wang

“…The novel SARS-CoV-2 Omicron variant (B.1.1.529), first found in early November 2021, has sparked considerable global concern and it has >50 mutations, many of…”
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Hypothesis for potential pathogenesis of SARS-CoV-2 infection-a review of immune changes in patients with viral pneumonia by Lin, Ling, Lu, Lianfeng, Cao, Wei, Li, Taisheng

“…Coronavirus disease 2019 (COVID-19) is an infectious disease caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) with droplets and contact…”
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Establishment and validation of a pseudovirus neutralization assay for SARS-CoV-2 by Nie, Jianhui, Li, Qianqian, Wu, Jiajing, Zhao, Chenyan, Hao, Huan, Liu, Huan, Zhang, Li, Nie, Lingling, Qin, Haiyang, Wang, Meng, Lu, Qiong, Li, Xiaoyu, Sun, Qiyu, Liu, Junkai, Fan, Changfa, Huang, Weijin, Xu, Miao, Wang, Youchun

“…Pseudoviruses are useful virological tools because of their safety and versatility, especially for emerging and re-emerging viruses. Due to its high…”
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Laboratory diagnosis of emerging human coronavirus infections - the state of the art by Loeffelholz, Michael J., Tang, Yi-Wei

“…The three unprecedented outbreaks of emerging human coronavirus (HCoV) infections at the beginning of the twenty-first century have highlighted the necessity…”
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The significant immune escape of pseudotyped SARS-CoV-2 variant Omicron by Zhang, Li, Li, Qianqian, Liang, Ziteng, Li, Tao, Liu, Shuo, Cui, Qianqian, Nie, Jianhui, Wu, Qian, Qu, Xiaowang, Huang, Weijin, Wang, Youchun

“…The emergence of Omicron/BA.1 has brought new challenges to fight against SARS-CoV-2. A large number of mutations in the Spike protein suggest that its…”
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Emerging WuHan (COVID-19) coronavirus: glycan shield and structure prediction of spike glycoprotein and its interaction with human CD26 by Vankadari, Naveen, Wilce, Jacqueline A

“…The recent outbreak of pneumonia-causing COVID-19 in China is an urgent global public health issue with an increase in mortality and morbidity. Here we report…”
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Renin-angiotensin system inhibitors improve the clinical outcomes of COVID-19 patients with hypertension by Meng, Juan, Xiao, Guohui, Zhang, Juanjuan, He, Xing, Ou, Min, Bi, Jing, Yang, Rongqing, Di, Wencheng, Wang, Zhaoqin, Li, Zigang, Gao, Hong, Liu, Lei, Zhang, Guoliang

“…The dysfunction of the renin-angiotensin system (RAS) has been observed in coronavirus infection disease (COVID-19) patients, but whether RAS inhibitors, such…”
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RNA based mNGS approach identifies a novel human coronavirus from two individual pneumonia cases in 2019 Wuhan outbreak by Chen, Liangjun, Liu, Weiyong, Zhang, Qi, Xu, Ke, Ye, Guangming, Wu, Weichen, Sun, Ziyong, Liu, Fang, Wu, Kailang, Zhong, Bo, Mei, Yi, Zhang, Wenxia, Chen, Yu, Li, Yirong, Shi, Mang, Lan, Ke, Liu, Yingle

“…From December 2019, an outbreak of unusual pneumonia was reported in Wuhan with many cases linked to Huanan Seafood Market that sells seafood as well as live…”
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Emerging COVID-19 coronavirus: glycan shield and structure prediction of spike glycoprotein and its interaction with human CD26 by Vankadari, Naveen, Wilce, Jacqueline A.

“…The recent outbreak of pneumonia-causing COVID-19 in China is an urgent global public health issue with an increase in mortality and morbidity. Here we report…”
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Colistin and its role in the Era of antibiotic resistance: an extended review (2000-2019) by El-Sayed Ahmed, Mohamed Abd El-Gawad, Zhong, Lan-Lan, Shen, Cong, Yang, Yongqiang, Doi, Yohei, Tian, Guo-Bao

“…Increasing antibiotic resistance in multidrug-resistant (MDR) Gram-negative bacteria (MDR-GNB) presents significant health problems worldwide, since the vital…”
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Kinetics of SARS-CoV-2 specific IgM and IgG responses in COVID-19 patients by Sun, Baoqing, Feng, Ying, Mo, Xiaoneng, Zheng, Peiyan, Wang, Qian, Li, Pingchao, Peng, Ping, Liu, Xiaoqing, Chen, Zhilong, Huang, Huimin, Zhang, Fan, Luo, Wenting, Niu, Xuefeng, Hu, Peiyu, Wang, Longyu, Peng, Hui, Huang, Zhifeng, Feng, Liqiang, Li, Feng, Zhang, Fuchun, Li, Fang, Zhong, Nanshan, Chen, Ling

“…The emerging COVID-19 caused by SARS-CoV-2 infection poses severe challenges to global public health. Serum antibody testing is becoming one of the critical…”
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COVID-19 pandemic - an African perspective by Lone, Shabir Ahmad, Ahmad, Aijaz

“…The recently emerged novel coronavirus, "severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2)", caused a highly contagious disease called coronavirus…”
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Identification of novel mobile colistin resistance gene mcr-10 by Wang, Chengcheng, Feng, Yu, Liu, Lina, Wei, Li, Kang, Mei, Zong, Zhiyong

“…Mobile colistin resistance (mcr) genes represent an emerging challenge. Here we describe a novel mcr gene, mcr-10, on an IncFIA plasmid of an Enterobacter…”
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ddPCR: a more accurate tool for SARS-CoV-2 detection in low viral load specimens by Suo, Tao, Liu, Xinjin, Feng, Jiangpeng, Guo, Ming, Hu, Wenjia, Guo, Dong, Ullah, Hafiz, Yang, Yang, Zhang, Qiuhan, Wang, Xin, Sajid, Muhanmmad, Huang, Zhixiang, Deng, Liping, Chen, Tielong, Liu, Fang, Xu, Ke, Liu, Yuan, Zhang, Qi, Liu, Yingle, Xiong, Yong, Chen, Guozhong, Lan, Ke, Chen, Yu

“…Quantitative real time PCR (RT-PCR) is widely used as the gold standard for clinical detection of SARS-CoV-2. However, due to the low viral load specimens and…”
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