Search Results - "Emeis, Jef J"

Dietary sphingolipids lower plasma cholesterol and triacylglycerol and prevent liver steatosis in APOE3Leiden mice by Duivenvoorden, Ilse, Voshol, Peter J, Rensen, Patrick CN, Duyvenvoorde, Wim van, Romijn, Johannes A, Emeis, Jef J, Havekes, Louis M, Nieuwenhuizen, Willem F

“…BACKGROUND: The prevalence of dyslipidemia and obesity resulting from excess energy intake and physical inactivity is increasing. The liver plays a pivotal…”
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Interaction of an annexin V homodimer (Diannexin) with phosphatidylserine on cell surfaces and consequent antithrombotic activity by Kuypers, Frans A, Larkin, Sandra K, Emeis, Jef J, Allison, Anthony C

“…Annexin V (AV), a protein with anticoagulant activity, exerts antithrombotic activity by binding to phosphatidylserine (PS), inhibiting activation of serine…”
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Use of fibrinolytic agents in the prevention of postoperative adhesion formation by Hellebrekers, B W, Trimbos-Kemper, T C, Trimbos, J B, Emeis, J J, Kooistra, T

“…To review the events leading to the formation of adhesions, to describe the development of fibrinolytic agents, to review more than a century of research on…”
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Simvastatin improves disturbed endothelial barrier function by VAN NIEUW AMERONGEN, Geerten P, VERMEER, Mario A, NEGRE-AMINOU, Pascale, LANKELMA, Jan, EMEIS, Jef J, VAN HINSBERGH, Victor W. M

“…Recent clinical trials have established that inhibitors of the enzyme 3-hydroxy-3-methylglutaryl coenzyme A reductase (statins) reduce the risk of acute…”
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A role for the fibrinolytic system in postsurgical adhesion formation by Hellebrekers, Bart W J, Emeis, Jef J, Kooistra, Teake, Trimbos, J Baptist, Moore, Norma R, Zwinderman, Koos H, Trimbos-Kemper, Trudy C M

“…To look for evidence of a fibrinolytic insufficiency as a cause of adhesion formation. Retrospective and prospective study. University medical center…”
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Increased urinary albumin excretion, endothelial dysfunction, and chronic low-grade inflammation in type 2 diabetes: Progressive, interrelated, and independently associated with risk of death by STEHOUWER, Coen D. A, GALL, Mari-Anne, TWISK, Jos W. R, KNUDSEN, Elisabeth, EMEIS, Jef J, PARVING, Hans-Henrik

“…In 328 type 2 diabetic patients followed for 9.0 years (mean), we investigated whether endothelial dysfunction and chronic inflammation (estimated from plasma…”
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Long-term effects of combined hormone replacement therapy on markers of endothelial function and inflammatory activity in healthy postmenopausal women by van Baal, W M, Kenemans, P, Emeis, J J, Schalkwijk, C G, Mijatovic, V, van der Mooren, M J, Vischer, U M, Stehouwer, C D

“…To study the effects of combined hormone replacement therapy on markers of endothelial function and inflammatory activity. Prospective, randomized, controlled…”
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Progression and regression of atherosclerosis in APOE3-Leiden transgenic mice: an immunohistochemical study by Gijbels, Marion J.J, van der Cammen, Maarten, van der Laan, Luc J.W, Emeis, Jef J, Havekes, Louis M, Hofker, Marten H, Kraal, Georg

“…Apolipoprotein E3-Leiden (APOE3-Leiden) transgenic mice develop hyperlipidemia and are highly susceptible to diet-induced atherosclerosis. We have studied the…”
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Rosuvastatin reduces atherosclerosis development beyond and independent of its plasma cholesterol-lowering effect in APOE3-Leiden transgenic mice: Evidence for antiinflammatory effects of rosuvastatin by KLEEMANN, Robert, PRINCEN, Hans M. G, EMEIS, Jef J, JUKEMA, J. Wouter, FONTIJN, Ruud D, HORREVOETS, Anton J. G, KOOISTRA, Teake, HAVEKES, Louis M

“…Statins can exert anti-inflammatory antiatherosclerotic effects through an anti-inflammatory action, independent of lowering cholesterol. We addressed the…”
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von Willebrand Factor, C-Reactive Protein, and 5-Year Mortality in Diabetic and Nondiabetic Subjects: The Hoorn Study by Jager, Agnes, van Hinsbergh, Victor W. M, Kostense, Piet J, Emeis, Jef J, Yudkin, John S, Nijpels, Giel, Dekker, Jacqueline M, Heine, Robert J, Bouter, Lex M, Stehouwer, Coen D. A

“…Increased levels of von Willebrand factor (vWf) and C-reactive protein (CRP) predict cardiovascular mortality in selected populations. It is uncertain whether…”
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Dual PPARα/γ Agonist Tesaglitazar Reduces Atherosclerosis in Insulin-Resistant and Hypercholesterolemic ApoE3Leiden Mice by Zadelaar, A Susanne M, Boesten, Lianne S.M, Jukema, J Wouter, van Vlijmen, Bart J.M, Kooistra, Teake, Emeis, Jef J, Lundholm, Erik, Camejo, German, Havekes, Louis M

“…OBJECTIVE—We investigated whether the dual PPARα/γ agonist tesaglitazar has anti-atherogenic effects in ApoE*3Leiden mice with reduced insulin sensitivity…”
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C-Reactive Protein and Soluble Vascular Cell Adhesion Molecule-1 Are Associated With Elevated Urinary Albumin Excretion but Do Not Explain Its Link With Cardiovascular Risk by Jager, Agnes, van Hinsbergh, Victor W.M, Kostense, Piet J, Emeis, Jef J, Nijpels, Giel, Dekker, Jacqueline M, Heine, Robert J, Bouter, Lex M, Stehouwer, Coen D.A

“…An elevated urinary albumin excretion rate (UAER) is associated with an increased risk of cardiovascular mortality, but the pathophysiological mechanism…”
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Increased C-reactive protein levels during short-term hormone replacement therapy in healthy postmenopausal women by van Baal, W M, Kenemans, P, van der Mooren, M J, Kessel, H, Emeis, J J, Stehouwer, C D

“…To study the short-term effect of unopposed oestradiol (E2) and sequentially combined hormone replacement therapy (E2 + P) on C-reactive protein (CRP) in…”
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Impaired procoagulant-anticoagulant balance during hormone replacement therapy? A randomised, placebo-controlled 12-week study by van Baal, W M, Emeis, J J, van der Mooren, M J, Kessel, H, Kenemans, P, Stehouwer, C D

“…In this randomised, placebo-controlled 12-week study, sixty healthy postmenopausal women received either placebo (N = 16) or daily 2 mg micronised oestradiol,…”
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Differential Effects of Amlodipine and Atorvastatin Treatment and Their Combination on Atherosclerosis in ApoE3-Leiden Transgenic Mice by Delsing, Dianne J. M, Jukema, Wouter J, van de Wiel, Mark A, Emeis, Jef J, van der Laarse, Arnoud, Havekes, Louis M, Princen, Hans M. G

“…This study was designed to investigate the potential antiatherosclerotic effects of the calcium antagonist amlodipine as compared with the HMG-CoA reductase…”
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Dietary sphingolipids lower plasma cholesterol and triacylglycerol and prevent liver steatosis by Nieuwenhuizen, Willem F., Duivenvoorden, Ilse, Voshol, Peter J., Rensen, Patrick C. N., van Duyvenvoorde, Wim, Romijn, Johannes A., Emeis, Jef J., Havekes, Louis M.

“…The prevalence of dyslipidemia and obesity resulting from excess energy intake and physical inactivity is increasing. The liver plays a pivotal role in the…”
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The effects of 12 weeks of HMR 3339, a novel selective estrogen receptor modulator, on markers of coagulation and fibrinolysis: A randomized, placebo-controlled, double-blind, dose-ranging study in healthy postmenopausal women by Vogelvang, Tatjana E., Mijatovic, Velja, Kenemans, Peter, Emeis, Jef J., Heijst, Johannes A., van der Mooren, Marius J.

“…To investigate the short-term effects of HMR 3339, a novel selective estrogen receptor modulator, on markers of coagulation and fibrinolysis. In a multicenter,…”
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Quantification of Plasminogen Activators and Their Inhibitors in the Aortic Vessel Wall in Relation to the Presence and Severity of Atherosclerotic Disease by Padro, Teresa, Emeis, Jef J, Steins, Martin, Schmid, Kurt W, Kienast, Jochen

“…Increased expression of plasminogen activator inhibitor-1 (PAI-1) has been demonstrated in the human atherosclerotic vessel wall and may contribute to the…”
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von Willebrand factor (vWf) as a plasma marker of endothelial activation in diabetes: improved reliability with parallel determination of the vWf propeptide (vWf:AgII) by Vischer, U M, Emeis, J J, Bilo, H J, Stehouwer, C D, Thomsen, C, Rasmussen, O, Hermansen, K, Wollheim, C B, Ingerslev, J

“…Elevated plasma von Willebrand factor (vWf) levels are found in diabetes and other vasculopathies, and predict cardiovascular mortality. vWf is stored and…”
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Progression of diabetic nephropathy: Role of plasma homocysteine and plasminogen activator inhibitor-1 by Hovind, Peter, Tarnow, Lise, Rossing, Peter, Teerlink, Tom, Stehouwer, Coen D.A., Emeis, Jef J., Parving, Hans-Henrik

“…Among patients with diabetic nephropathy, the decline in glomerular filtration rate (GFR) varies substantially, ranging from 2 to 20 mL/min per year…”
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