Search Results - "Emberton, M."

SP-0020: Is there a role for focal treatment in prostate cancer?: The urologist point of view by Emberton, M

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Focal therapy for localized prostate cancer: a phase I/II trial by Ahmed, H U, Freeman, A, Kirkham, A, Sahu, M, Scott, R, Allen, C, Van der Meulen, J, Emberton, M

“…Men with localized prostate cancer currently face a number of treatment options that treat the entire prostate. These can cause significant sexual and urinary…”
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Magnetic resonance imaging targeted transperineal prostate biopsy: a local anaesthetic approach by Bass, E J, Donaldson, I A, Freeman, A, Jameson, C, Punwani, S, Moore, C, Arya, M, Emberton, M, Ahmed, H U

“…Background: Despite high rates of disease misclassification and sepsis, the use of transrectal biopsy remains commonplace. Transperineal mapping biopsies…”
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Initial assessment of safety and clinical feasibility of irreversible electroporation in the focal treatment of prostate cancer by Valerio, M, Stricker, P D, Ahmed, H U, Dickinson, L, Ponsky, L, Shnier, R, Allen, C, Emberton, M

“…Background: To evaluate the safety and clinical feasibility of focal irreversible electroporation (IRE) of the prostate. Methods: We assessed the toxicity…”
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TOOKAD® Soluble focal therapy: pooled analysis of three phase II studies assessing the minimally invasive ablation of localized prostate cancer by Azzouzi, A. R., Barret, E., Bennet, J., Moore, C., Taneja, S., Muir, G., Villers, A., Coleman, J., Allen, C., Scherz, A., Emberton, M.

“…Purpose To evaluate the 6-month effects of the recommended drug and light dosage in focal vascular-targeted photodynamic therapy (VTP) using TOOKAD ® Soluble…”
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Survival after postoperative morbidity: a longitudinal observational cohort study by Moonesinghe, S.R., Harris, S., Mythen, M.G., Rowan, K.M., Haddad, F.S., Emberton, M., Grocott, M.P.W.

“…Previous studies have suggested that there may be long-term harm associated with postoperative complications. Uncertainty exists however, because of the need…”
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Intratumoural evolutionary landscape of high-risk prostate cancer: the PROGENY study of genomic and immune parameters by Linch, M., Goh, G., Hiley, C., Shanmugabavan, Y., McGranahan, N., Rowan, A., Wong, Y.N.S., King, H., Furness, A., Freeman, A., Linares, J., Akarca, A., Herrero, J., Rosenthal, R., Harder, N., Schmidt, G., Wilson, G.A., Birkbak, N.J., Mitter, R., Dentro, S., Cathcart, P., Arya, M., Johnston, E., Scott, R., Hung, M., Emberton, M., Attard, G., Szallasi, Z., Punwani, S., Quezada, S.A., Marafioti, T., Gerlinger, M., Ahmed, H.U., Swanton, C.

“…Intratumoural heterogeneity (ITH) is well recognised in prostate cancer (PC), but its role in high-risk disease is uncertain. A prospective, single-arm,…”
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Medium-term Follow-up of Vascular-targeted Photodynamic Therapy of Localized Prostate Cancer Using TOOKAD Soluble WST-11 (Phase II Trials) by Noweski, A., Roosen, A., Lebdai, S., Barret, E., Emberton, M., Benzaghou, F., Apfelbeck, M., Gaillac, B., Gratzke, C., Stief, C., Azzouzi, A.R.

“…To assess the medium-term tumor control in patients with localized prostate cancer (PCa) treated with vascular-targeted photodynamic (VTP) therapy with TOOKAD…”
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Medical treatment of benign prostatic hyperplasia: physician and patient preferences and satisfaction by Emberton, M

“…Practice guidelines acknowledge the importance of patient preferences in determining the appropriate treatment of benign prostatic hyperplasia (BPH). Recent…”
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Multiparametric MRI for detection of radiorecurrent prostate cancer: added value of apparent diffusion coefficient maps and dynamic contrast-enhanced images by Abd-Alazeez, M, Ramachandran, N, Dikaios, N, Ahmed, H U, Emberton, M, Kirkham, A, Arya, M, Taylor, S, Halligan, S, Punwani, S

“…Background: Multiparametric magnetic resonance imaging (mp-MRI) is increasingly advocated for prostate cancer detection. There are limited reports of its use…”
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Intraprostatic Cancer Recurrence following Radical Radiotherapy on Transperineal Template Mapping Biopsy: Implications for Focal Ablative Salvage Therapy by Kanthabalan, A, Arya, M, Freeman, A, Mitra, A V, Payne, H, Peters, M, Shah, T T, Emberton, M, Ahmed, H U

“…Men in whom external beam radiotherapy fails are usually placed on delayed hormone therapy. Some of these men have localized recurrence that might be suitable…”
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High-intensity-focused ultrasound in the treatment of primary prostate cancer: the first UK series by Ahmed, H U, Zacharakis, E, Dudderidge, T, Armitage, J N, Scott, R, Calleary, J, Illing, R, Kirkham, A, Freeman, A, Ogden, C, Allen, C, Emberton, M

“…Background: The use of minimally invasive ablative therapies in localised prostate cancer offer potential for a middle ground between active surveillance and…”
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The Postoperative Morbidity Survey was validated and used to describe morbidity after major surgery by Grocott, M.P.W, Browne, J.P, Van der Meulen, J, Matejowsky, C, Mutch, M, Hamilton, M.A, Levett, D.Z.H, Emberton, M, Haddad, F.S, Mythen, M.G

“…Abstract Objectives To describe the reliability and validity of the Postoperative Morbidity Survey (POMS). To describe the level and pattern of short-term…”
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Focal Therapy for Prostate Cancer: Rationale and Treatment Opportunities by Kasivisvanathan, V, Emberton, M, Ahmed, H.U

“…Abstract Focal therapy is an emerging treatment modality for localised prostate cancer that aims to reduce the morbidity seen with radical therapy, while…”
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The importance of lesion conspicuity in prostate cancer risk assessment by Emberton, M., Stavrinides, V., Norris, J.

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Performance of multiparametric MRI in men at risk of prostate cancer before the first biopsy: a paired validating cohort study using template prostate mapping biopsies as the reference standard by Abd-Alazeez, M, Kirkham, A, Ahmed, H U, Arya, M, Anastasiadis, E, Charman, S C, Freeman, A, Emberton, M

“…Background: Multiparametric magnetic resonance imaging (mpMRI) has the potential to serve as a non-invasive triage test for men at risk of prostate cancer. Our…”
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Photodynamic therapy for focal ablation of the prostate by Arumainayagam, Nimalan, Moore, C. M., Ahmed, Hashim U., Emberton, M.

“…Although in early stages of clinical development, photodynamic therapy (PDT) shows promise in delivering focal treatment of both primary and post-radiotherapy…”
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Photodynamic therapy using meso tetra hydroxy phenyl chlorin (mTHPC) in early prostate cancer by Moore, C.M., Nathan, T.R., Lees, W.R., Mosse, C.A., Freeman, A., Emberton, M., Bown, S.G.

“…Background and Objectives Prostate cancer is increasing in incidence, but current treatments including surgery and radiotherapy have significant side effects…”
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Focal therapy in prostate cancer-report from a consensus panel by de la Rosette, J, Ahmed, H, Barentsz, J, Johansen, T Bjerklund, Brausi, M, Emberton, M, Frauscher, F, Greene, D, Harisinghani, M, Haustermans, K, Heidenreich, A, Kovacs, G, Mason, M, Montironi, R, Mouraviev, V, de Reijke, T, Taneja, S, Thuroff, S, Tombal, B, Trachtenberg, J, Wijkstra, H, Polascik, T

“…To establish a consensus in relation to case selection, conduct of therapy, and outcomes that are associated with focal therapy for men with localized prostate…”
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The Prevalence of Clinically Significant Prostate Cancer According to Commonly Used Histological Thresholds in Men Undergoing Template Prostate Mapping Biopsies by Valerio, M, Anele, C, Bott, S.R.J, Charman, S.C, van der Meulen, J, El-Mahallawi, H, Emara, A.M, Freeman, A, Jameson, C, Hindley, R.G, Montgomery, B.S.I, Singh, P.B, Ahmed, H.U, Emberton, M

“…Purpose Transrectal prostate biopsies are inaccurate and, thus, the prevalence of clinically significant prostate cancer in men undergoing biopsy is unknown…”
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