Search Results - "Emanuelli, Andres"

Unilateral Cataract and Retinitis Pigmentosa in a Patient With Polyneuropathy, Hearing Loss, Ataxia, Retinitis Pigmentosa, and Cataract (PHARC) Syndrome: A Case Report by Hernández-Emanuelli, Miguel E, Emanuelli, Andres, Izquierdo, Natalio

“…Patients with mutations in the α/β hydrolase  gene develop ocular complications including cataracts and retinitis pigmentosa (RP), as part of the…”
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Nd:YAG Laser Hyaloidotomy: A Therapeutic Approach for Valsalva Premacular Hemorrhage by Hernández-Emanuelli, Miguel E, Echegaray, Jose J, Emanuelli, Andres

“…Subhyaloid hemorrhage, characterized by localized vitreoretinal detachment due to blood accumulation, often results in sudden vision loss, especially in the…”
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Structure-based virtual screening workflow to identify antivirals targeting HIV-1 capsid by Sun, Qinfang, Biswas, Avik, Vijayan, R. S. K., Craveur, Pierrick, Forli, Stefano, Olson, Arthur J., Castaner, Andres Emanuelli, Kirby, Karen A., Sarafianos, Stefan G., Deng, Nanjie, Levy, Ronald

“…We have identified novel HIV-1 capsid inhibitors targeting the PF74 binding site. Acting as the building block of the HIV-1 capsid core, the HIV-1 capsid…”
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Potency and metabolic stability: a molecular hybrid case in the design of novel PF74-like small molecules targeting HIV-1 capsid protein by Sahani, Rajkumar Lalji, Akther, Thamina, Cilento, Maria E, Castaner, Andres Emanuelli, Zhang, Huanchun, Kirby, Karen A, Xie, Jiashu, Sarafianos, Stefan G, Wang, Zhengqiang

“…PF74 ( 1 ) is a potent and well-characterized prototypical small molecule targeting human immunodeficiency virus type 1 (HIV-1) capsid protein (CA), but not a…”
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Expanding the phenotype of TTLL5-associated retinal dystrophy: a case series by Oh, Jin Kyun, Vargas Del Valle, José G, Lima de Carvalho, Jr, Jose Ronaldo, Sun, Young Joo, Levi, Sarah R, Ryu, Joseph, Yang, Jing, Nagasaki, Takayuki, Emanuelli, Andres, Rasool, Nailyn, Allikmets, Rando, Sparrow, Janet R, Izquierdo, Natalio J, Duncan, Jacque L, Mahajan, Vinit B, Tsang, Stephen H

“…Inherited retinal dystrophies describe a heterogeneous group of retinal diseases that lead to the irreversible degeneration of rod and cone photoreceptors and…”
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Design, Synthesis and Characterization of HIV-1 CA-Targeting Small Molecules: Conformational Restriction of PF74 by Sahani, Rajkumar Lalji, Diana-Rivero, Raquel, Vernekar, Sanjeev Kumar V, Wang, Lei, Du, Haijuan, Zhang, Huanchun, Castaner, Andres Emanuelli, Casey, Mary C, Kirby, Karen A, Tedbury, Philip R, Xie, Jiashu, Sarafianos, Stefan G, Wang, Zhengqiang

“…Small molecules targeting the PF74 binding site of the HIV-1 capsid protein (CA) confer potent and mechanistically unique antiviral activities. Structural…”
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Evaluation of cardiac parameters and other safety outcomes of brolucizumab treatment in patients with neovascular age‐related macular degeneration by Zakaria, Nadia, Guerard, Nicolas, Emanuelli, Andres, Dugel, Pravin, Watts, Jen, Liew, Melissa, Gekkieva, Margarita, Hinder, Markus

“…This was a prospective, single‐dose, single‐arm, open‐label, non‐randomized, multicenter clinical study to determine cardiovascular safety after a single…”
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Reactivation of Acute Retinal Necrosis following SARS-CoV-2 Infection by Gonzalez, Monica P., Rios, Radames, Pappaterra, Mariella, Hernandez, Miguel, Toledo, Allison, Santos, Carmen, Emanuelli, Andres, Kurup, Shree K., Oliver, Armando L.

“…Purpose. To report on a case of reactivation of acute retinal necrosis following SARS-CoV-2 infection. Methods. Observational case report. Observations. A…”
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Optical coherence tomography angiography findings in macular toxoplasma retinochoroiditis: A case report by Perez, Alejandro L., Lozada, Rosa A., Emanuelli, Andres, Oliver, Armando L.

“…To report the optical coherence tomography angiography (OCT-A) findings in a patient with macular toxoplasma retinochoroiditis (TRC). A 14-year old female…”
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KESTREL and KITE: 52-Week Results From Two Phase III Pivotal Trials of Brolucizumab for Diabetic Macular Edema by Brown, David M., Emanuelli, Andrés, Bandello, Francesco, Barranco, Jose Juan Escobar, Figueira, João, Souied, Eric, Wolf, Sebastian, Gupta, Vishali, Ngah, Nor Fariza, Liew, Gerald, Tuli, Raman, Tadayoni, Ramin, Dhoot, Dilsher, Wang, Lixin, Bouillaud, Emmanuel, Wang, Ying, Kovacic, Lidija, Guerard, Nicolas, Garweg, Justus G.

“…To compare the efficacy and safety of brolucizumab with aflibercept in patients with diabetic macular edema (DME). Double-masked, 100-week, multicenter,…”
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Unilateral choroidal neovascular membrane as a herald lesion for Crohn's disease by Thomas, Benjamin J, Emanuelli, Andres A, Berrocal, Audina M

“…Crohn's disease is a diffuse inflammatory disease primarily affecting the gastrointestinal tract but with associated ophthalmologic complications that often…”
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Efficacy and Safety of Brolucizumab for Diabetic Macular Edema: The KINGFISHER Randomized Clinical Trial by Singh, Rishi P, Barakat, Mark R, Ip, Michael S, Wykoff, Charles C, Eichenbaum, David A, Joshi, Sunir, Warrow, David, Sheth, Veeral S, Stefanickova, Jana, Kim, Yong Soo, He, Fanyin, Cho, Ga Eun, Wang, Yuhua, Emanuelli, Andrés

“…Despite the effectiveness of existing anti-vascular endothelial growth factor (VEGF) therapies, a need remains for further treatment options to improve…”
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Genetic analysis of patients with nonsyndromic and syndromic retinitis pigmentosa in Puerto Rico: a genetic legacy by Vargas, José Gustavo, Izquierdo, Natalio J., Oliver, Armando, Muns, Sofia, Garcia-Rodriguez, Omar, Villegas, Víctor, Emanuelli, Andrés

“…BACKGROUNDRetinitis pigmentosa (RP) is a genetically heterogeneous group of diseases characterized by complete progressive vision loss; it has a prevalence of…”
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Management of 2 intraocular lenses in the same eye by Emanuelli, Andrés, Smiddy, William E

“…To present options for managing a patient with a dislocated intraocular lens (IOL) in the presence of a second, nondislocated IOL. A review of 3 consecutive…”
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Evaluation of Intravitreal Aflibercept for the Treatment of Severe Nonproliferative Diabetic Retinopathy: Results From the PANORAMA Randomized Clinical Trial by Brown, David M, Wykoff, Charles C, Boyer, David, Heier, Jeffrey S, Clark, W Lloyd, Emanuelli, Andres, Higgins, Patrick M, Singer, Michael, Weinreich, David M, Yancopoulos, George D, Berliner, Alyson J, Chu, Karen, Reed, Kimberly, Cheng, Yenchieh, Vitti, Robert

“…Proactive treatment of nonproliferative diabetic retinopathy (NPDR) reduces the risk of progression to vision-threatening complications. To evaluate vascular…”
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Characteristics Upon Presentation of Patients with Type 2 Macular Telangiectasia in Puerto Rico by González-Martínez, Orlando G, Ortiz, Jan, Quiñones, Sebastián, Alicea, Jonathan G, Guevara, Francisco, Pérez, Alejandro, Pappaterra, Mariella, Requejo-Figueroa, Guillermo A, Amaral, Claudia, Rivera-Grana, Erick, Villegas, Victor M, Quiñones, Cesar, Emanuelli, Andrés, Oliver, Armando L

“…To describe the systemic disease associations and clinical features upon initial presentation of a cohort of patients with type 2 macular telangiectasia who…”
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Retinitis Pigmentosa Associated With EYS Gene Mutations in Puerto Rico: A Case Series by Ruiz-Justiz, Armando J, Molina Thurin, Leonardo J, Emanuelli, Andres, Izquierdo, Natalio

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Efficacy and Safety of Intraoperative Mitomycin C as Adjunct Therapy for Pterygium Surgery by Díaz, Lilliam, Villegas, Víctor M, Emanuelli, Andrés, Izquierdo, Natalio J

“…PURPOSES:The primary objective of this study was to determine if intraoperative application of mitomycin C (MMC) is safe as an adjunct for pterygium surgery…”
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Intravitreal aflibercept 8 mg in diabetic macular oedema (PHOTON): 48-week results from a randomised, double-masked, non-inferiority, phase 2/3 trial by Brown, David M, Boyer, David S, Wykoff, Charles C, Sakamoto, Taiji, Win, Peter, Joshi, Sunir, Salehi-Had, Hani, Seres, András, Berliner, Alyson J, Leal, Sergio, Rao, Rohini, Cheng, Yenchieh, Sun, Wei, Voronca, Delia, Bhore, Rafia, Schmidt-Ott, Ursula, Schmelter, Thomas, Schulze, Andrea, Zhang, Xin, Yancopoulos, George D, Abraham, Prema, Aderman, Christopher, Akiyama, Kunihiko, Alfaro, Daniel V., Amini, Payam, Anzalotta, Andres Emanuelli, Berger, Adam, Bhandari, Ramanath, Bridges, William, Brinkmann, Christian, Brown, Jamin, Capone Jr, Antonio, Cervena, Dana, Charles, Steven, Chaudhry, Nauman, Cunningham, Matthew, Dessouki, Amr, Deupree, Dana, Eichenbaum, David, Ernest, Jan, Fenberg, Moss, Ferrone, Philip, Gasperini, Julie, Gerstenblith, Adam, Goff, Mitchell, Golas, Liliya, Goren Fein, Jordana, Hagiwara, Akira, Hairston, Richard, Hau, Vivienne, Hayashi, Ken, Heier, Jeffrey, Hershberger, Vrinda, Higgins, Patrick, Ikegami, Yasuko, Ishida, Yuichiro, Ishii, Kiyoshi, Jain, Atul, Kaji, Yuichi, Kapoor, Kapil, Kimura, Kazuhiro, Kishino, Genichiro, Klancnik, James M., Kobayashi, Namie, Korda, Vladimir, Kruger, Erik, Lee, Seong, Mein, Calvin, Milibák, Tibor, Mitamura, Yoshinori, Murata, Toshinori, Noge, Sumiyo, Onoe, Hajime, Papp, András, Patel, Sugat, Patel, Sunil, Pezda, Matthew, Prasad, Pradeep, Schadlu, Ramin, Shah, Ankur, Shah, Milan, Sharma, Ashish, Sheth, Veeral, Spital, Georg, Stoltz, Robert, Suan, Eric, Suzuma, Kiyoshi, Takamura, Yoshihiro, Takeuchi, Masaru, Tan, Jeffrey, Thomas, Benjamin, Tóth,-Molnár, Edit, Ushida, Hiroaki, Varma, Deepali, Varsányi, Balázs, Weber, Pamela, Wee, Raymond, Williams, Geoff, Yonekawa, Yoshihiro, Yoshida, Shigeo

“…A high-dose formulation of intravitreal aflibercept (8 mg) could improve treatment outcomes in diabetic macular oedema (DMO) by requiring fewer injections than…”
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Low-dose methotrexate for the treatment of chronic central serous chorioretinopathy: a retrospective analysis by Kurup, Shree K, Oliver, Armando, Emanuelli, Andres, Hau, Vincent, Callanan, David

“…To evaluate the utility of oral methotrexate (MTX) for the treatment of chronic central serous chorioretinopathy (CSCR). Retrospective review of all eyes of…”
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