Search Results - "Emala, C."

Inhaled Bile Acids are Implicated in Airway Functional Changes and Cytokine Release by Urso, A., Emala, C., D'Ovidio, F.

“…Bile acids are potent TGR5 ligands previously identified in bronchial washings of post-lung transplant patients and have been implicated in airway…”
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Renal tubule necrosis and apoptosis modulation by A1 adenosine receptor expression by Lee, H.T., Kim, M., Jan, M., Penn, R.B., Emala, C.W.

“…We have shown that A1 adenosine receptors (A1ARs) are cytoprotective against renal tubular necrosis and apoptosis both in vivo and in vitro. To study the role…”
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Lipopolysaccharide-induced sensitization of adenylyl cyclase activity in murine macrophages by Osawa, Y, Lee, H T, Hirshman, C A, Xu, D, Emala, C W

“…LPS is known to modulate macrophage responses during sepsis, including cytokine release, phagocytosis, and proliferation. Although agents that elevate cAMP…”
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Protective effects of renal ischemic preconditioning and adenosine pretreatment: role of A(1) and A(3) receptors by Lee, H T, Emala, C W

“…Renal ischemia and reperfusion during aortic and renal transplant surgery result in ischemic-reperfusion injury. Ischemic preconditioning and adenosine…”
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Oxytocin and Lysophosphatidic Acid Induce Stress Fiber Formation in Human Myometrial Cells via a Pathway Involving Rho-Kinase by GOGARTEN, Wiebke, EMALA, Charles W, LINDEMAN, Karen S, HIRSHMAN, Carol A

“…The actin cytoskeleton is important for stress fiber formation and contributes to the initiation and maintenance of smooth muscle contraction. To determine if…”
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Glucocorticoid treatment decreases muscarinic receptor expression in canine airway smooth muscle by Emala, C W, Clancy, J, Hirshman, C A

“…Corticosteroids upregulate the beta-adrenergic pathway, but little is known about corticosteroid regulation of muscarinic pathways. Basenji-greyhound (BG) dogs…”
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Neuromuscular relaxants as antagonists for M2 and M3 muscarinic receptors by HOU, V. Y, HIRSHMAN, C. A, EMALA, C. W

“…Neuromuscular relaxants such as pancuronium bind to M2 and M3 muscarinic receptors as antagonists. Blockade of muscarinic receptors in atria of the M2 subtype…”
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Systemic adenosine given after ischemia protects renal function via A(2a) adenosine receptor activation by Lee, H T, Emala, C W

“…Ischemia and reperfusion during renal transplant and aortic surgery result in renal ischemic-reperfusion injury. Previously, we showed that preischemic…”
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TNF-alpha inhibits isoproterenol-stimulated adenylyl cyclase activity in cultured airway smooth muscle cells by Emala, C W, Kuhl, J, Hungerford, C L, Hirshman, C A

“…Inflammation, increased cytokine production, and decreased responsiveness of airway smooth muscle (ASM) to beta-adrenergic agonists are characteristics of…”
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C35 ASTHMA AND ALLERGY CELLULAR INVESTIGATIONS: Antagonism Of The Tmem16a Calcium-Activated Chloride Channel Attenuates Allergic Lung Inflammation by Danielsson, J, Mikami, M, Emala, C W

“…Rationale: TMEM16A is an important calcium-activated chloride channel expressed in both airway smooth muscle and airway epithelium. Methods: C57/BL6 mice were…”
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Abnormal pattern of Tie-2 and vascular endothelial growth factor receptor expression in human cerebral arteriovenous malformations by HASHIMOTO, Tomoki, EMALA, Charles W, MEGYESI, Joseph F, FINDLAY, J. Max, SELMAN, Warren R, THOMAS, Jeffrey E, JOSHI, Shailendra, MESA-TEJADA, Ricardo, QUICK, Christopher M, LEI FENG, LIBOW, Adam, MARCHUK, Douglas A, YOUNG, William L, AWAD, Issam A

“…Human cerebral arteriovenous malformations (AVMs) are speculated to result from abnormal angiogenesis. Vascular endothelial growth factor receptors (VEGF-Rs)…”
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Adenylyl Cyclase Messenger Ribonucleic Acid in Myometrium: Splice Variant of Type IV by EMALA, C. W, KUMASAKA, D, HIRSHMAN, C. A, LINDEMAN, K. S

“…Regulation of uterine tone during pregnancy and parturition involves G protein-coupled receptors that modulate cellular levels of cAMP. Cyclic AMP is…”
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Qualitative immunoblot analysis of PKC isoforms expressed in airway smooth muscle by Togashi, H, Hirshman, C A, Emala, C W

“…Protein kinase C (PKC) was originally identified as a single serine/ threonine protein kinase with calcium- and phospholipid-dependent activity, but more…”
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Actin depolymerization via the beta-adrenoceptor in airway smooth muscle cells: a novel PKA-independent pathway by Hirshman, C A, Zhu, D, Panettieri, R A, Emala, C W

“…Actin is a major functional and structural cytoskeletal protein that mediates such diverse processes as motility, cytokinesis, contraction, and control of cell…”
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C19 NEW SENSATIONS IN THE LUNG: THE GOOD, THE BAD, AND THE NERVE: Modulation Of Airway Smooth Muscle Tone And Proliferation With Transient Receptor Potential (trp) V1 Ligands by Yocum, G T, Zhang, Y, Emala, C

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Cellular signaling by the potent bronchoconstrictor endothelin-1 in airway smooth muscle by Fehr, James J, Hirshman, Carol A, Emala, Charles W

“…OBJECTIVEThe objective of this study was to determine whether the potent bronchoconstrictor endothelin-1 was coupled to the activation of the inositol…”
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Impaired activation of adenylyl cyclase in lung of the Basenji-greyhound model of airway hyperresponsiveness : decreased numbers of high affinity β-adrenoceptors by EMALA, C. W, ARYANA, A, HIRSHMAN, C. A

“…1. To evaluate mechanisms involved in the impaired beta-adrenoceptor stimulation of adenylyl cyclase in tissues from the Basenji-greyhound (BG) dog model of…”
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Expression of adenylyl cyclase V/VI mRNA and protein is upregulated in cyanotic infant human myocardium by Zhao, Y, Xu, D, Quaegebeur, J M, Emala, C W, Sun, L S

“…We have previously demonstrated that both basal and isoproterenol-stimulated activities of myocardial adenylyl cyclase were greater in cyanotic patients with…”
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C67 FUNCTIONAL MAPPING OF SMOOTH MUSCLE CONTRACTOME AND RELAXOME: Inhalation Of The Flavonol Galangin Inhibits Murine In Vivo Bronchoconstriction by Brown, A, Gallos, G, Danielsson, J, Emala, C

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C67 FUNCTIONAL MAPPING OF SMOOTH MUSCLE CONTRACTOME AND RELAXOME: A Comparison Of The Action Of Capsazepine, A Putative Trpv1 Antagonist And Skf96365, A Store-Operated Calcium Entry (soce) Antagonist On Soce, Ca2+ Oscillations And Contraction Of Airway Smooth Muscle In Mouse Precision-Cut Lung Slices (pclss) by Chen, J, Yocum, G T, Emala, C, Sanderson, M J

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