Search Results - "Elwakeel, Ahmed"

Abrogating the Interaction Between p53 and Mortalin (Grp75/HSPA9/mtHsp70) for Cancer Therapy: The Story so far by Elwakeel, Ahmed

“…p53 is a transcription factor that activates the expression of a set of genes that serve as a critical barrier to oncogenesis. Inactivation of p53 is the most…”
Get full text

Soyasapogenol-A targets CARF and results in suppression of tumor growth and metastasis in p53 compromised cancer cells by Omar, Amr, Kalra, Rajkumar Singh, Putri, Jayarani, Elwakeel, Ahmed, Kaul, Sunil C., Wadhwa, Renu

“…We screened some phytochemicals for cytotoxic activity to human cancer cells and identified Soyasapogenol-A (Snol-A) as a potent candidate anti-cancer…”
Get full text

Formulation and characterization of propolis and tea tree oil nanoemulsion loaded with clindamycin hydrochloride for wound healing: In-vitro and in-vivo wound healing assessment by Abdellatif, Menna M., Elakkad, Yara E., Elwakeel, Ahmed A., Allam, Rasha M., Mousa, Mohamed R.

“…This study aimed to develop propolis and tea tree oil nanoemulsion loaded with clindamycin hydrochloride to heal wound effectively. Nanoemulsion formulae were…”
Get full text

Marine Carotenoid Fucoxanthin Possesses Anti-Metastasis Activity: Molecular Evidence by Garg, Sukant, Afzal, Sajal, Elwakeel, Ahmed, Sharma, Damini, Radhakrishnan, Navaneethan, Dhanjal, Jaspreet Kaur, Sundar, Durai, Kaul, Sunil C, Wadhwa, Renu

“…Fucoxanthin is commonly found in marine organisms; however, to date, it has been one of the scarcely explored natural compounds. We investigated its activities…”
Get full text

Metabolites of Cannabis Induce Cardiac Toxicity and Morphological Alterations in Cardiac Myocytes by Merve, Ayse Orme, Sobiecka, Pola, Remeškevičius, Vytautas, Taylor, Luke, Saskoy, Lili, Lawton, Scott, Jones, Ben P, Elwakeel, Ahmed, Mackenzie, Francesca E, Polycarpou, Elena, Bennett, Jason, Rooney, Brian

“…Cannabis is one of the most commonly used recreational drugs worldwide. Rrecent epidemiology studies have linked increased cardiac complications to cannabis…”
Get full text

Measuring COVID-19 as Traumatic Stress: Initial Psychometrics and Validation by Kira, Ibrahim A., Shuwiekh, Hanaa A. M., Rice, Kenneth G., Ashby, Jeffrey S., Elwakeel, Sayed Ahmed, Sous, Mariam Sous Fahmy, Alhuwailah, Amthal, Baali, Shadia Bint Ali, Azdaou, Chafika, Oliemat, Enas. M., Jamil, Hikmet J.

“…The goal was to develop and validate a measure for COVID-19 as traumatic stress. The scale consisted of three dimensions: "threat/fear of infection and death,"…”
Get full text

Differentiation of Capripox Viruses by Nanopore Sequencing by Eltom, Kamal H, Althoff, Anna Christina, Hansen, Sören, Böhlken-Fascher, Susanne, Yousif, Ausama, El-Sheikh, Hussein A, ElWakeel, Ahmed A, Elgamal, Mahmoud A, Mossa, Hadeer M, Aboul-Soud, Emad A, Wolff, Janika, Korthase, Christian, Hoffmann, Bernd, Adam, Nabawia M, Abdelaziz, Sanaa A, Shalaby, Mohamed A, Abd El Wahed, Ahmed

“…The genus capripoxvirus (CaPV), family , includes three virus species: goatpox virus (GPV), sheeppox virus (SPV) and lumpy skin disease virus (LSDV). CaPV…”
Get full text

Rheumatic tricuspid valve disease: Repair versus Replacement by Elwakeel, Ahmed M., El Midany, Ashraf A.H., El-Sokkary, Ismail N., Mahmoud, Mohamed El-Hossiny, Elkhonezy, Bahaa A., Abdelmoaty, Haytham M., Badawi, Mohammed Wael, Hikal, Tamer, Ahmed, Mohamed H., Khaled, Ahmed A., ElSaid, Mohammed E., Gamil, Ibrahim K., khadrawy, Mahmoud, Elwakeel, Mahmoud, Mahmoud, Eman, Lamloom, Ahmed H.

“…Background: Tricuspid valve disease is most commonly functional, however, organic affection still accounts for one fourth of cases. Rheumatic fever which is…”
Get full text

Unlocking Dendritic Cell-Based Vaccine Efficacy through Genetic Modulation-How Soon Is Now? by Elwakeel, Ahmed, Bridgewater, Hannah E, Bennett, Jason

“…The dendritic cell (DC) vaccine anti-cancer strategy involves tumour-associated antigen loading and maturation of autologous ex vivo cultured DCs, followed by…”
Get full text

Identification and Characterization of MortaparibPlus—A Novel Triazole Derivative That Targets Mortalin-p53 Interaction and Inhibits Cancer-Cell Proliferation by Wild-Type p53-Dependent and -Independent Mechanisms by Sari, Anissa Nofita, Elwakeel, Ahmed, Dhanjal, Jaspreet Kaur, Kumar, Vipul, Sundar, Durai, Kaul, Sunil C., Wadhwa, Renu

“…p53 has an essential role in suppressing the carcinogenesis process by inducing cell cycle arrest/apoptosis/senescence. Mortalin/GRP75 is a member of the Hsp70…”
Get full text

A Low Dose Combination of Withaferin A and Caffeic Acid Phenethyl Ester Possesses Anti-Metastatic Potential In Vitro: Molecular Targets and Mechanisms by Sari, Anissa Nofita, Dhanjal, Jaspreet Kaur, Elwakeel, Ahmed, Kumar, Vipul, Meidinna, Hazna Noor, Zhang, Huayue, Ishida, Yoshiyuki, Terao, Keiji, Sundar, Durai, Kaul, Sunil C, Wadhwa, Renu

“…Withaferin A (Wi-A) and Caffeic Acid Phenethyl Ester (CAPE) are the bioactive ingredients of Ashwagandha ( ) and propolis, respectively. Both of these natural…”
Get full text

Reinforced Aortic Root Reconstruction in Type A Aortic Dissection: A Prospective Study by Elsharkawy, Ahmed, El Midany, Ashraf, Elwakeel, Ahmed, Mahmoud, Eman, Mohammed, Ahmed, Nasr, Sherif

“…Type A aortic dissection is a challenging surgical emergency associated with high morbidity and mortality. Many techniques have evolved to repair the dissected…”
Get more information

Identification and Characterization of Mortaparib Plus -A Novel Triazole Derivative That Targets Mortalin-p53 Interaction and Inhibits Cancer-Cell Proliferation by Wild-Type p53-Dependent and -Independent Mechanisms by Sari, Anissa Nofita, Elwakeel, Ahmed, Dhanjal, Jaspreet Kaur, Kumar, Vipul, Sundar, Durai, Kaul, Sunil C, Wadhwa, Renu

“…p53 has an essential role in suppressing the carcinogenesis process by inducing cell cycle arrest/apoptosis/senescence. Mortalin/GRP75 is a member of the Hsp70…”
Get full text

Implementation of the Chou-Talalay method for studying the in vitro pharmacodynamic interactions of binary and ternary drug combinations on MDA-MB-231 triple negative breast cancer cells by Elwakeel, Ahmed, Soudan, Hadeer, Eldoksh, Ahmad, Shalaby, Manal, Eldemellawy, Maha, Ghareeb, Doaa, Abouseif, Myriam, Fayad, Amira, Hassan, Mostafa, Saeed, Hesham

“…[Display omitted] Triple Negative Breast Cancer (TNBC) treatment is more challenging than other subtypes of breast malignancy and due to the lack of markers…”
Get full text

Mutant p53L194F Harboring Luminal-A Breast Cancer Cells Are Refractory to Apoptosis and Cell Cycle Arrest in Response to MortaparibPlus, a Multimodal Small Molecule Inhibitor by Elwakeel, Ahmed, Sari, Anissa Nofita, Dhanjal, Jaspreet Kaur, Meidinna, Hazna Noor, Sundar, Durai, Kaul, Sunil C., Wadhwa, Renu

“…We previously performed a drug screening to identify a potential inhibitor of mortalin–p53 interaction. In four rounds of screenings based on the shift in…”
Get full text

English Bullying en la educación superior, bullying universitario by Sefa Bulut, Pietro Crescenzo, Baidi Bukhori, Sayed Ahmed Elwakeel, Kemale Salmanova

“…Objetivo: Este estudio tuvo como objetivo explorar los incidentes de intimidación y maltrato de estudiantes universitarios por parte de miembros de la…”
Get full text

The Impact of COVID-19 Traumatic Stressors on Mental Health: Is COVID-19 a New Trauma Type by Kira, Ibrahim A., Shuwiekh, Hanaa A.M., Ashby, Jeffrey S., Elwakeel, Sayed Ahmed, Alhuwailah, Amthal, Sous, Mariam Sous Fahmy, Baali, Shadia Bint Ali, Azdaou, Chafika, Oliemat, Enas. M., Jamil, Hikmet J.

“…COVID-19 is a new type of trauma that has never been conceptually or empirically analyzed in our discipline. This study aimed to investigate the impact of…”
Get full text