Search Results - "Elvin, T."

Crosslinking of base-modified RNAs by synthetic DYW-KP base editors implicates an enzymatic lysine as the nitrogen donor for U-to-C RNA editing by Hayes, Michael L., Garcia, Elvin T., Chun, Skellie O., Selke, Matthias

“…Sequence-specific cytidine to uridine (C-to-U) and adenosine to inosine editing tools can alter RNA and DNA sequences and utilize a hydrolytic deamination…”
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Epigenetic regulation of drug metabolism in aging: utilizing epigenetics to optimize geriatric pharmacotherapy by Abudahab, Sara, Slattum, Patricia W, Price, Elvin T, McClay, Joseph L

“…We explore the relationship between epigenetic aging and drug metabolism. We review current evidence for changes in drug metabolism in normal aging, followed…”
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Dietary Bioactive Fatty Acids as Modulators of Immune Function: Implications on Human Health by Kumar, Naren Gajenthra, Contaifer, Daniel, Madurantakam, Parthasarathy, Carbone, Salvatore, Price, Elvin T, Van Tassell, Benjamin, Brophy, Donald F, Wijesinghe, Dayanjan S

“…Diet is major modifiable risk factor for cardiovascular disease that can influence the immune status of the individual and contribute to persistent low-grade…”
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Warfarin pharmacogenomics and African ancestry by Price, Elvin T.

“…In this issue of Blood, Limdi and coauthors demonstrate that racially informed warfarin pharmacogenetic algorithms perform better than traditional algorithms,…”
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Demonstrated value in the public health arena: Pharmacist roles in addressing the current opioid crisis by Price, Elvin T.

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"I Have Come Because I See You Care About Me": Recruiting Older Black Americans for Genomic Research by Winship, Jodi M, Mackiewicz, Marissa, Babar, Muhammad, Dixon, Dave L, Price, Elvin T, Sargent, Lana J

“…The lack of diversity in genomic studies is a disparity that influences our understanding of human genomic variation and threatens equity in the benefits of…”
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The blood neutrophil to lymphocyte ratio correlates with clinical status in children with cystic fibrosis: a retrospective study by O'Brien, Catherine E, Price, Elvin T

“…The blood neutrophil to lymphocyte ratio (NLR) has been identified as a potentially useful marker of clinical outcome in disease states with an inflammatory…”
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Comparing Quality of Life in Breast Cancer Patients Who Underwent Mastectomy Versus Breast-Conserving Surgery: A Meta-Analysis by Ng, Elvin T, Ang, Russell Z, Tran, Bach X, Ho, Cyrus S, Zhang, Zhisong, Tan, Wanqiu, Bai, Yu, Zhang, Min, Tam, Wilson W, Ho, Roger C

“…The purpose of our study was to carry out a meta-analysis of current literature to determine whether total mastectomy and breast-conserving surgery induce…”
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Quality of life in older adults with opioid use disorder: A scoping review by Mackiewicz, Marissa, Brown, Roy E., Price, Elvin T., Sargent, Lana

“…•Substance use and opioid use disorders negatively impacts QOL older adults.•There are a paucity of evidence-based interventions for improving QOL in older…”
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Bringing Transdisciplinary Aging Research From Theory to Practice by Sargent, Lana, Slattum, Patricia, Brooks, Marshall, Gendron, Tracey, Mackiewicz, Marissa, Diallo, Ana, Waters, Leland, Winship, Jodi, Battle, Kimberly, Ford, Gregory, Falls, Katherine, Chung, Jane, Zanjani, Faika, Pretzer-Aboff, Ingrid, Price, Elvin T, Prom-Wormley, Elizabeth, Parsons, Pamela

“…Abstract There is a growing emphasis to use a transdisciplinary team approach to accelerate innovations in science to solve complex conditions associated with…”
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Influence of physiological and psychological factors on cognitive dysfunction in heart failure patients by Sargent, Lana, Flattery, Maureen, Shah, Keyur, Price, Elvin T., Tirado, Camila, Oliveira, Tadeau, Starkweather, Angela, Salyer, Jeanne

“…Our study aimed to examine factors that contribute to cognitive dysfunction in patients with heart failure (HF). Although a majority of patients with HF have…”
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Sex and Age Differences in Ambulatory Blood Pressure Monitoring Tolerability by Khaddage, Sarah J, Patterson, Julie A, Sargent, Lana J, Price, Elvin T, Dixon, Dave L

“…Abstract BACKGROUND Clinical practice guidelines endorse using ambulatory blood pressure monitoring (ABPM) for the diagnosis and management of hypertension…”
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Response to George Thomas’s review of The Lovers’ Quarrel: The Two Foundings and American Political Development by Lim, Elvin T.

“…Professor Thomas claims that the Two Foundings do not stand as starkly opposed to each other as I have argued. He accepts that "these conceptual clashes are…”
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Gene expression variability in human hepatic drug metabolizing enzymes and transporters by Yang, Lun, Price, Elvin T, Chang, Ching-Wei, Li, Yan, Huang, Ying, Guo, Li-Wu, Guo, Yongli, Kaput, Jim, Shi, Leming, Ning, Baitang

“…Interindividual variability in the expression of drug-metabolizing enzymes and transporters (DMETs) in human liver may contribute to interindividual…”
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Histone acetylation at the sulfotransferase 1a1 gene is associated with its hepatic expression in normal aging by Kronfol, Mohamad M., Abudahab, Sara, Dozmorov, Mikhail G., Jahr, Fay M., Halquist, Matthew S., McRae, MaryPeace, Wijesinghe, Dayanjan S., Price, Elvin T., Slattum, Patricia W., McClay, Joseph L.

“…Phase II drug metabolism is poorly studied in advanced age and older adults may exhibit significant variability in their expression of phase II enzymes. We…”
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Low-Income Older Adults’ Vulnerability to Anticholinergic Medication-Associated Frailty by Sargent, Lana, Zimmerman, Kristin M., Mohammed, Almutairi, Barrett, Matthew J., Nawaz, Huma, Wyman-Chick, Kathryn, Mackiewicz, Marissa, Roman, Youssef, Slattum, Patricia, Russell, Sally, Dixon, Dave L., Lageman, Sarah K., Hobgood, Sarah, Thacker, Leroy R., Price, Elvin T.

“…Background A growing body of research supports the negative impact of anticholinergic drug burden on physical frailty. However, prior research has been limited…”
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Antimuscarinic Anticholinergic Medications in Parkinson Disease: To Prescribe or Deprescribe? by Barrett, Matthew J., Sargent, Lana, Nawaz, Huma, Weintraub, Daniel, Price, Elvin T., Willis, Allison W.

“…ABSTRACT The relative importance of antimuscarinic anticholinergic medications for Parkinson's disease (PD) declined after the introduction of levodopa, such…”
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Gastric Bypass Increases Circulating Bile Acids and Activates Hepatic Farnesoid X Receptor (FXR) but Requires Intact Peroxisome Proliferator Activator Receptor Alpha (PPARα) Signaling to Significantly Reduce Liver Fat Content by Mazzini, Guilherme S., Khoraki, Jad, Browning, Matthew G., Wu, Jilin, Zhou, Huiping, Price, Elvin T., Wolfe, Luke G., Mangino, Martin J., Campos, Guilherme M.

“…Background We interrogate effects of gastric bypass (RYGB), compared with a low-calorie diet, on bile acid (BA), liver fat, and FXR, PPARα, and targets in rats…”
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Challenges in pharmacotherapy for older adults: a framework for pharmacogenomics implementation by Roman, Youssef M, Dixon, Dave L, Salgado, Teresa M, Price, Elvin T, Zimmerman, Kristin M, Sargent, Lana, Slattum, Patricia W

“…Older adults are at high risk for inappropriate prescribing, developing polypharmacy, adverse drug events and poor treatment outcomes due to multimorbidity and…”
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Pharmacogenomics in Clinical Practice for Older People by Hashimi, Syeda R, Babatunde, Olajumoke, Alrajeh, Khalifa, Dixon, Richard J, Okpeku, Aimalohi, Price, Elvin T

“…Older people are over-represented among individuals that experience adverse drug reactions (ADR) and adverse drug events (ADE). Furthermore, older people are…”
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