Search Results - "Elsocht, Mathias"

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    Structure-Activity Relationship (SAR) Study of Spautin-1 to Entail the Discovery of Novel NEK4 Inhibitors by Elsocht, Mathias, Giron, Philippe, Maes, Laila, Versées, Wim, Gutierrez, Gustavo J, De Grève, Jacques, Ballet, Steven

    “…Lung cancer is one of the most frequently diagnosed cancers accounting for the highest number of cancer-related deaths in the world. Despite significant…”
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    Journal Article
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    Propargylamine Amino Acids as Constrained N ε‑Substituted Lysine Mimetics by Van holsbeeck, Kevin, Elsocht, Mathias, Ballet, Steven

    Published in Organic letters (13-01-2023)
    “…Herein, alkylated propargylamines are reported as constrained lysine mimetics and constructed in a single step using a copper­(I)-catalyzed A3-coupling…”
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    Journal Article
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    Second generation Spautin-1 analogues targeting EGFR-mutant non-small cell lung cancer cells by Elsocht, Mathias, Giron, Philippe, De Grève, Jacques, Ballet, Steven

    Published in Bioorganic & medicinal chemistry letters (01-01-2023)
    “…Treatment of advanced stage epidermal growth factor receptor (EGFR)-mutant non-small cell lung cancer (NSCLC) is often complicated by the occurrence of…”
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    Journal Article