Search Results - "Elsharkawy, Ahmed M"

Gender Disparity in Liver Cancer Due to Sex Differences in MyD88-Dependent IL-6 Production by Naugler, Willscott E, Sakurai, Toshiharu, Kim, Sunhwa, Maeda, Shin, Kim, KyoungHyun, Elsharkawy, Ahmed M, Karin, Michael

“…Hepatocellular carcinoma (HCC), the most common liver cancer, occurs mainly in men. Similar gender disparity is seen in mice given a chemical carcinogen,…”
Get full text

Metabolic dysfunction and cancer in HCV: Shared pathways and mutual interactions by Leslie, Jack, Geh, Daniel, Elsharkawy, Ahmed M., Mann, Derek A., Vacca, Michele

“…HCV hijacks many host metabolic processes in an effort to aid viral replication. The resulting hepatic metabolic dysfunction underpins many of the hepatic and…”
Get full text

Sarcopenia in chronic liver disease: mechanisms and countermeasures by Allen, Sophie L, Quinlan, Jonathan I, Dhaliwal, Amritpal, Armstrong, Matthew J, Elsharkawy, Ahmed M, Greig, Carolyn A, Lord, Janet M, Lavery, Gareth G, Breen, Leigh

“…Sarcopenia, a condition of low muscle mass, quality, and strength, is commonly found in patients with cirrhosis and is associated with adverse clinical…”
Get more information

Summary of the British Transplantation Society UK Guidelines for Hepatitis E and Solid Organ Transplantation by McPherson, Stuart, Elsharkawy, Ahmed M., Ankcorn, Michael, Ijaz, Samreen, Powell, James, Rowe, Ian, Tedder, Richard, Andrews, Peter A.

“…ABSTRACTThe incidence and prevalence of hepatitis E virus (HEV) infection has increased in many developed countries over the last decade, predominantly due to…”
Get full text

Accelerated aging of skeletal muscle and the immune system in patients with chronic liver disease by Nicholson, Thomas, Dhaliwal, Amritpal, Quinlan, Jonathan I., Allen, Sophie L., Williams, Felicity R., Hazeldine, Jon, McGee, Kirsty C., Sullivan, Jack, Breen, Leigh, Elsharkawy, Ahmed M., Armstrong, Matthew J., Jones, Simon W., Greig, Carolyn A., Lord, Janet M.

“…Patients with chronic liver disease (CLD) often present with significant frailty, sarcopenia, and impaired immune function. However, the mechanisms driving the…”
Get full text

Impaired lower limb muscle mass, quality and function in end stage liver disease: A cross‐sectional study by Quinlan, Jonathan I., Dhaliwal, Amritpal, Williams, Felicity R., Allen, Sophie L., Choudhary, Surabhi, Rowlands, Alex, Breen, Leigh, Lavery, Gareth G., Lord, Janet M., Elsharkawy, Ahmed M., Armstrong, Matthew J., Greig, Carolyn A.

“…New Findings What is the central question of this study? To what extent does musculoskeletal impairment occur (i.e., muscle mass, quality and function) in…”
Get full text

Assessment of ultrasound-guided tru-cut needle pleural biopsy in the diagnosis of unexplained exudative pleural effusion compared to medical thoracoscopy by Elaraby, Mostafa B, Elsharkawy, Ahmed M, Attia, Ghada A, Ganna, Salwa A

“…Background Ultrasound-guided needle biopsy (USGNB) allows for precise and immediate viewing of pleural lesions, effusions, and needle placement without…”
Get full text

Feasibility, Efficacy, and Safety of Percutaneous Muscle Biopsies in Patients With Chronic Liver Disease by Quinlan, Jonathan I, Dhaliwal, Amritpal, Williams, Felicity, Allen, Sophie L, Breen, Leigh, Greig, Carolyn A, Lord, Janet M, Armstrong, Matthew J, Elsharkawy, Ahmed M

“…Sarcopenia is present in many chronic disease states including decompensated end stage liver disease (ESLD) and non-cirrhotic non-alcoholic fatty liver disease…”
Get full text

Multigenerational epigenetic adaptation of the hepatic wound-healing response by Zeybel, Müjdat, Hardy, Timothy, Wong, Yi K, Mathers, John C, Fox, Christopher R, Gackowska, Agata, Oakley, Fiona, Burt, Alastair D, Wilson, Caroline L, Anstee, Quentin M, Barter, Matt J, Masson, Steven, Elsharkawy, Ahmed M, Mann, Derek A, Mann, Jelena

Get full text

Evaluation of the mechanisms of sarcopenia in chronic inflammatory disease: protocol for a prospective cohort study by Dhaliwal, Amritpal, Williams, Felicity R, Quinlan, Jonathan I, Allen, Sophie L, Greig, Carolyn, Filer, Andrew, Raza, Karim, Ghosh, Subrata, Lavery, Gareth G, Newsome, Philip N, Choudhary, Surabhi, Breen, Leigh, Armstrong, Matthew J, Elsharkawy, Ahmed M, Lord, Janet M

“…Several chronic inflammatory diseases co-exist with and accelerate sarcopenia (reduction in muscle strength, function and mass) and negatively impact on both…”
Get full text

Management of hepatitis C genotype 4 in the directly acting antivirals era by Hathorn, Emma, Elsharkawy, Ahmed M

“…Genotype 4 chronic hepatitis C (G4 HCV) accounts for 13% of worldwide HCV infections; with 10 million people infected with the virus across the world. Up to…”
Get full text

The Impact of Slice Interval and Equation on the Accuracy of Magnetic Resonance Image Estimation of Quadriceps Muscle Volume in End Stage Liver Disease by Quinlan, Jonathan I., Jones, Clare, Bissonnette, Emma, Dhaliwal, Amritpal, Williams, Felicity, Choudhary, Surabhi, Breen, Leigh, Lavery, Gareth G., Armstrong, Matthew J., Elsharkawy, Ahmed M., Lord, Janet M., Greig, Carolyn A.

“…Introduction End stage liver disease (ESLD) is associated with loss of muscle mass and function, known as sarcopenia, which can increase the risk of…”
Get full text

Comparison between the outcome of single versus multiple uterine fibroids after uterine artery embolization by Elsharkawy, Ahmed M, Elsaeed, Haytham H, Kamel, Ahmed H, Morgan, Robert, Elshafey, Mohamed H

“…Background Uterine fibroids are the most common benign tumor of the reproductive tract in women. Uterine artery embolization has been approved as an…”
Get full text

Nuclear factor‐κB and the hepatic inflammation‐fibrosis‐cancer axis by Elsharkawy, Ahmed M., Mann, Derek A.

“…Nuclear factor‐κB (NF‐κB) is a transcriptional regulator of genes involved in immunity, inflammatory response, cell fate, and function. Recent attention has…”
Get full text

EASL position paper on clinical follow-up after HCV cure by Reiberger, Thomas, Lens, Sabela, Cabibbo, Giuseppe, Nahon, Pierre, Zignego, Anna Linda, Deterding, Katja, Elsharkawy, Ahmed M., Forns, Xavier

“…Following the advent of direct-acting antivirals (DAAs), hepatitis C virus (HCV) infection can be cured in almost all infected patients. This has led to a…”
Get full text

Antifibrotic therapy in nonalcoholic steatohepatitis: time for a human-centric approach by Brennan, Paul N., Elsharkawy, Ahmed M., Kendall, Timothy J., Loomba, Rohit, Mann, Derek A., Fallowfield, Jonathan A.

“…Nonalcoholic steatohepatitis (NASH) might soon become the leading cause of end-stage liver disease and indication for liver transplantation worldwide. Fibrosis…”
Get full text

SARS-CoV-2: Is the liver merely a bystander to severe disease? by Bangash, Mansoor N., Patel, Jaimin M., Parekh, Dhruv, Murphy, Nicholas, Brown, Rachel M., Elsharkawy, Ahmed M., Mehta, Gautam, Armstrong, Matthew J., Neil, Desley

Get full text

The Micro-Elimination Approach to Eliminating Hepatitis C: Strategic and Operational Considerations by Lazarus, Jeffrey V, Safreed-Harmon, Kelly, Thursz, Mark R, Dillon, John F, El-Sayed, Manal H, Elsharkawy, Ahmed M, Hatzakis, Angelos, Jadoul, Michel, Prestileo, Tullio, Razavi, Homie, Rockstroh, Jürgen K, Wiktor, Stefan Z, Colombo, Massimo

“…The introduction of efficacious new hepatitis C virus (HCV) treatments galvanized the World Health Organization to define ambitious targets for eliminating HCV…”
Get more information

Hepatitis C Virus Epidemiology and the Impact of Interferon-Free Hepatitis C Virus Therapy by Lazarus, Jeffrey V, Roel, Elena, Elsharkawy, Ahmed M

“…The public health impact of hepatitis C virus (HCV) infection has been realized only recently. Globally, 71 million people are living with HCV chronic…”
Get full text

Multigenerational epigenetic adaptation of the hepatic wound-healing response by Zeybel, Müjdat, Hardy, Timothy, Wong, Yi K, Mathers, John C, Fox, Christopher R, Gackowska, Agata, Oakley, Fiona, Burt, Alastair D, Wilson, Caroline L, Anstee, Quentin M, Barter, Matt J, Masson, Steven, Elsharkawy, Ahmed M, Mann, Derek A, Mann, Jelena

“…Derek Mann and his colleagues have found that experimental induction of liver fibrosis in male rats results in an epigenetic modification of the chromatin in…”
Get full text