Search Results - "Elsen, Gina E."

Intermediate Progenitor Cohorts Differentially Generate Cortical Layers and Require Tbr2 for Timely Acquisition of Neuronal Subtype Identity by Mihalas, Anca B., Elsen, Gina E., Bedogni, Francesco, Daza, Ray A.M., Ramos-Laguna, Kevyn A., Arnold, Sebastian J., Hevner, Robert F.

“…Intermediate progenitors (IPs) amplify the production of pyramidal neurons, but their role in selective genesis of cortical layers or neuronal subtypes remains…”
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Tbr1 regulates regional and laminar identity of postmitotic neurons in developing neocortex by Bedogni, Francesco, Hodge, Rebecca D., Elsen, Gina E., Nelson, Branden R., Daza, Ray A. M., Beyer, Richard P., Bammler, Theo K., Rubenstein, John L. R., Hevner, Robert F., Rakic, Pasko

“…Areas and layers of the cerebral cortex are specified by genetic programs that are initiated in progenitor cells and then, implemented in postmitotic neurons…”
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protomap is propagated to cortical plate neurons through an Eomes-dependent intermediate map by Elsen, Gina E., Hodge, Rebecca D., Bedogni, Francesco, Daza, Ray A. M., Nelson, Branden R., Shiba, Naoko, Reiner, Steven L., Hevner, Robert F.

“…The cortical area map is initially patterned by transcription factor (TF) gradients in the neocortical primordium, which define a “protomap” in the embryonic…”
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The Epigenetic Factor Landscape of Developing Neocortex Is Regulated by Transcription Factors Pax6→ Tbr2→ Tbr1 by Elsen, Gina E, Bedogni, Francesco, Hodge, Rebecca D, Bammler, Theo K, MacDonald, James W, Lindtner, Susan, Rubenstein, John L R, Hevner, Robert F

“…Epigenetic factors (EFs) regulate multiple aspects of cerebral cortex development, including proliferation, differentiation, laminar fate, and regional…”
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Unipolar (Dendritic) Brush Cells Are Morphologically Complex and Require Tbr2 for Differentiation and Migration by McDonough, Ashley, Elsen, Gina E, Daza, Ray M, Bachleda, Amelia R, Pizzo, Donald, DelleTorri, Olivia M, Hevner, Robert F

“…Previous studies demonstrated specific expression of transcription factor Tbr2 in unipolar brush cells (UBCs) of the cerebellum during development and…”
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Stable respiratory activity requires both P/Q-type and N-type voltage-gated calcium channels by Koch, Henner, Zanella, Sebastien, Elsen, Gina E, Smith, Lincoln, Doi, Atsushi, Garcia, 3rd, Alfredo J, Wei, Aguan D, Xun, Randy, Kirsch, Sarah, Gomez, Christopher M, Hevner, Robert F, Ramirez, Jan-Marino

“…P/Q-type voltage-gated calcium channels (Ca(v)2.1) play critical presynaptic and postsynaptic roles throughout the nervous system and have been implicated in a…”
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Zic1 and Zic4 regulate zebrafish roof plate specification and hindbrain ventricle morphogenesis by Elsen, Gina E., Choi, Louis Y., Millen, Kathleen J., Grinblat, Yevgenya, Prince, Victoria E.

“…During development, the lumen of the neural tube develops into a system of brain cavities or ventricles, which play important roles in normal CNS function. We…”
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Model Organisms Inform the Search for the Genes and Developmental Pathology Underlying Malformations of the Human Hindbrain by Aldinger, Kimberly A., PhD, Elsen, Gina E., PhD, Prince, Victoria E., PhD, Millen, Kathleen J., PhD

“…Congenital malformations of the human hindbrain, including the cerebellum, are poorly understood largely because their recognition is a relatively recent…”
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Zebrafish Hoxb1a regulates multiple downstream genes including prickle1b by Rohrschneider, Monica R., Elsen, Gina E., Prince, Victoria E.

“…Despite 30 years of Hox gene study, we have a remarkably limited knowledge of the downstream target genes that Hox transcription factors regulate to confer…”
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Tbr2 expression in Cajal-Retzius cells and intermediate neuronal progenitors is required for morphogenesis of the dentate gyrus by Hodge, Rebecca D, Garcia, 3rd, Alfredo J, Elsen, Gina E, Nelson, Branden R, Mussar, Kristin E, Reiner, Steven L, Ramirez, Jan-Marino, Hevner, Robert F

“…The dentate gyrus (DG) is a unique cortical region whose protracted development spans the embryonic and early postnatal periods. DG development involves…”
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Neurog2 simultaneously activates and represses alternative gene expression programs in the developing neocortex by Kovach, Christopher, Dixit, Rajiv, Li, Saiqun, Mattar, Pierre, Wilkinson, Grey, Elsen, Gina E, Kurrasch, Deborah M, Hevner, Robert F, Schuurmans, Carol

“…Progenitor cells undergo a series of stable identity transitions on their way to becoming fully differentiated cells with unique identities. Each cellular…”
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The autism susceptibility gene met regulates zebrafish cerebellar development and facial motor neuron migration by Elsen, Gina E., Choi, Louis Y., Prince, Victoria E., Ho, Robert K.

“…During development, Met signaling regulates a range of cellular processes including growth, differentiation, survival and migration. The Met gene encodes a…”
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Conditional ablation of Tbr2 results in abnormal development of the olfactory bulbs and subventricular zone‐rostral migratory stream by Kahoud, Robert J., Elsen, Gina E., Hevner, Robert F., Hodge, Rebecca D.

“…Background Development of the olfactory bulb (OB) is a complex process that requires contributions from several progenitor cell niches to generate neuronal…”
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Ptf1a is a molecular determinant for both glutamatergic and GABAergic neurons in the hindbrain by Aldinger, Kimberly A, Elsen, Gina E

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cMet signaling functions during zebrafish hindbrain development by Elsen, Gina E., Choi, Louis Y., Prince, Victoria E., Ho, Robert K.

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