Search Results - "Else, K.J."

Immunity to Trichuris muris in the laboratory mouse by Else, K J, deSchoolmeester, M L

“…Of all the laboratory models of intestinal nematode infection, Trichuris muris in the mouse is arguably the most powerful. This is largely due to the fact that…”
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Caveolin1 interacts with the glucocorticoid receptor in the lung but is dispensable for its anti-inflammatory actions in lung inflammation and Trichuris Muris infection by Caratti, G., Poolman, T., Hurst, R. J., Ince, L., Knight, A., Krakowiak, K., Durrington, H. J., Gibbs, J., Else, K. J., Matthews, L. C., Ray, D. W.

“…Glucocorticoids (Gcs) are widely prescribed anti-inflammatory compounds, which act through the glucocorticoid receptor (GR). Using an unbiased proteomics…”
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Regulation of colonic epithelial cell turnover by IDO contributes to the innate susceptibility of SCID mice to Trichuris muris infection by BELL, L.V, ELSE, K.J

“…Tryptophan catabolism via the kynurenine pathway is dependent on the enzyme Indoleamine 2,3-dioxygenase (IDO). Expression of IDO is upregulated in a number of…”
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Modulation of cytokine production and response phenotypes in murine trichuriasis by Else, K J, Hültner, L, Grencis, R K

“…BALB/K mice are usually resistant to infection with the intestinal nematode parasite Trichuris muris and exhibit a Th2 dominated (IL-5, IL-9) response…”
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Trichuris muris: antigen recognition and transfer of immunity in mice by IgA monoclonal antibodies by Roach, T I, Else, K J, Wakelin, D, McLaren, D J, Grencis, R K

“…Mesenteric node lymphocytes from mice that had been infected with the nematode Trichuris muris, and then boosted with adult worm excretory-secretory antigens…”
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Mechanisms of leucocyte recruitment to the inflamed large intestine: redundancy in integrin and addressin usage by BELL, L.V, ELSE, K.J

“…The caecal-dwelling nematode Trichuris muris provides a natural model of human whipworm infection. Resistance to T. muris is dependent on a host Th2 response,…”
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Antigen selection for future anti-Trichuris vaccines: a comparison of cytokine and antibody responses to larval and adult antigen in a primary infection by DIXON, H, JOHNSTON, C.E, ELSE, K.J

“…Trichuriasis, caused by the whipworm Trichuris trichiura, is endemic in tropical and subtropical areas, affecting approximately 1 billion people. Child…”
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Cytokine response profiles predict species-specific infection patterns in human GI nematodes by Jackson, J.A., Turner, J.D., Rentoul, L., Faulkner, H., Behnke, J.M., Hoyle, M., Grencis, R.K., Else, K.J., Kamgno, J., Bradley, J.E., Boussinesq, M.

“…This study investigated associations between pre-treatment cytokine expression and infection patterns, before and after de-worming, in humans exposed to two…”
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Altered antibody responses in mannose-binding lectin-A deficient mice do not affect Trichuris muris or Schistosoma mansoni infections by LAWRENCE, R.A, CARTER, T, BELL, L.V, ELSE, K.J, SUMMERFIELD, J, BICKLE, Q

“…Parasitic helminths possess surface glycoconjugates that are recognized by the serum collectin molecule, mannose-binding lectin (MBL). Once bound, MBL triggers…”
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Invited review Intestinal nematode parasites, cytokines and effector mechanisms by Else, K.J, Finkelman, Fred D

“…Laboratory models of intestinal nematode infection have played an important role in developing our understanding of the immune mechanisms that operate against…”
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Correlations between worm burden and markers of Th1 and Th2 cell subset induction in an inbred strain of mouse infected with Trichuris muris by Else, K J, Entwistle, G M, Grencis, R K

“…Helper T cell subset induction was examined within a single inbred strain of mouse (B10.D2/n) where individuals varied in their ability to expel the nematode…”
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Cytokine production in BALB/c mice immunized with radiation attenuated third stage larvae of the filarial nematode, Brugia pahangi by Bancroft, AJ, Grencis, RK, Else, KJ, Devaney, E

“…BALB/c mice immunized with radiation attenuated third stage larvae of the filarial nematode Brugia pahangi are strongly immune to challenge infection…”
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Genetic influences upon eosinophilia and resistance in mice infected with Trichinella spiralis by Lammas, D A, Wakelin, D, Mitchell, L A, Tuohy, M, Else, K J, Grencis, R K

“…Genetic influences upon host variation in eosinophilia and resistance to helminth infection, and the relationship between these parameters, were investigated…”
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Antigenic cross-reactivity between the human whipworm, Trichuris trichiura, and the mouse trichuroids Trichuris muris and Trichinella spiralis by Roach, T I, Wakelin, D, Else, K J, Bundy, D A

“…Cross-reactivity was demonstrated between circulating antibodies from Trichuris trichiura-infected humans and T. muris-infected mice for heterologous antigen…”
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MHC-restricted antibody responses to Trichuris muris excretory/secretory (E/S) antigen by Else, K J, Wakelin, D, Wassom, D L, Hauda, K M

“…Two panels of H-2 recombinant mice were used in a detailed serological study to analyse the role of H-2-linked genes in the control of the antibody response to…”
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