Search Results - "Elsayed, Mustafa"
-
1
Development of topical therapeutics for management of onychomycosis and other nail disorders: A pharmaceutical perspective
Published in Journal of controlled release (10-02-2015)“…The human nail plate is a formidable barrier to drug permeation. Development of therapeutics for management of nail diseases thus remains a challenge. This…”
Get full text
Journal Article -
2
Modeling the performance of carrier-based dry powder inhalation formulations: Where are we, and how to get there?
Published in Journal of controlled release (10-06-2018)“…Development of carrier-based dry powder inhalation formulations follows till date empirical approaches. This is mainly underlain by numerousness of…”
Get full text
Journal Article -
3
Deformable liposomes and ethosomes: Mechanism of enhanced skin delivery
Published in International journal of pharmaceutics (28-09-2006)“…Despite intensive research, the mechanisms by which vesicular systems deliver drugs into intact skin are not yet fully understood. In the current study,…”
Get full text
Journal Article -
4
Microstructural characterization of carrier-based dry powder inhalation excipients: Insights and guidance
Published in International journal of pharmaceutics (10-09-2019)“…[Display omitted] The growing interest in development of dry powder inhalation (DPI) products raises a need for development of standard testing methods and…”
Get full text
Journal Article -
5
Natural Polymeric Nanoparticles for Brain-Targeting: Implications on Drug and Gene Delivery
Published in Current pharmaceutical design (01-06-2016)“…There is a broad range of biological, chemical and physical hurdles for drugs to reach the brain. Nanoparticulate drug delivery systems hold tremendous…”
Get more information
Journal Article -
6
Critical attributes of fine excipient materials in carrier-based dry powder inhalation formulations: The particle shape and surface properties
Published in International journal of pharmaceutics (25-04-2024)“…[Display omitted] The potential of fine excipient materials to improve the aerodynamic performance of carrier-based dry powder inhalation (DPI) formulations is…”
Get full text
Journal Article -
7
Insights into the potential of rheological measurements in development of dry powder inhalation formulations
Published in International journal of pharmaceutics (25-02-2022)“…[Display omitted] Study of flow is a key to development of dry powder inhalation formulations. Various static (bulk) and dynamic rheological measurements are…”
Get full text
Journal Article -
8
The vesicle-to-micelle transformation of phospholipid–cholate mixed aggregates: A state of the art analysis including membrane curvature effects
Published in Biochimica et biophysica acta (01-01-2011)“…We revisited the vesicle-to-micelle transformation in phosphatidylcholine–cholate mixtures paying special attention to the lipid bilayer curvature effects. For…”
Get full text
Journal Article -
9
Particle Engineering by Nano Spray Drying: Optimization of Process Parameters with Hydroethanolic versus Aqueous Solutions
Published in Pharmaceutics (06-04-2022)“…Nano spray drying has emerged as an outstanding platform for engineering micro- and nanoparticles, with growing applications in various areas of drug delivery…”
Get full text
Journal Article -
10
Turbidity Spectroscopy for Characterization of Submicroscopic Drug Carriers, Such as Nanoparticles and Lipid Vesicles: Size Determination
Published in Pharmaceutical research (01-09-2011)“…ABSTRACT Purpose To apply UV/Vis spectrometry for characterization of submicroscopic drug carriers, such as nanoparticles and lipid vesicles. Methods We first…”
Get full text
Journal Article -
11
The effect of membrane softeners on rigidity of lipid vesicle bilayers: Derivation from vesicle size changes
Published in Chemistry and physics of lipids (01-01-2018)“…[Display omitted] •A simple method for quantifying the effect of bilayer softeners on deformability of bilayer vesicles is proposed.•The bending rigidity of…”
Get full text
Journal Article -
12
A New Role of Fine Excipient Materials in Carrier-Based Dry Powder Inhalation Mixtures: Effect on Deagglomeration of Drug Particles During Mixing Revealed
Published in AAPS PharmSciTech (01-11-2017)“…The potential of fine excipient materials to improve the performance of carrier-based dry powder inhalation mixtures is well acknowledged. The mechanisms…”
Get full text
Journal Article -
13
Modification of graphene oxide with imidazolium-based ionic liquid for significant sorption of La(III) and Pr(III) from aqueous solutions
Published in Applied water science (01-07-2023)“…A straightforward ferrocyanide immobilization on the surface of graphene oxide (GO) was conducted for rapid and efficient adsorption capacity for lanthanum and…”
Get full text
Journal Article -
14
Insights into the roles of carrier microstructure in adhesive/carrier-based dry powder inhalation mixtures: Carrier porosity and fine particle content
Published in European journal of pharmaceutics and biopharmaceutics (01-10-2015)“…[Display omitted] To gain insights into complex interactions in carrier-based dry powder inhalation mixtures, we studied the relationships between the carrier…”
Get full text
Journal Article -
15
Inhalable microparticles containing terbinafine for management of pulmonary fungal infections: Spray drying process engineering using lactose vs. mannitol as excipients
Published in Journal of drug delivery science and technology (01-12-2020)“…Terbinafine is a broad-spectrum antifungal agent with potential therapeutic value in management of pulmonary aspergillosis. To this end, dry powder inhalation…”
Get full text
Journal Article -
16
Inhalable, Spray-Dried Terbinafine Microparticles for Management of Pulmonary Fungal Infections: Optimization of the Excipient Composition and Selection of an Inhalation Device
Published in Pharmaceutics (30-12-2021)“…Terbinafine is a broad-spectrum antifungal agent with therapeutic potential against pulmonary aspergillosis. The main aim of the current study was to…”
Get full text
Journal Article -
17
Fine excipient materials in carrier-based dry powder inhalation formulations: The interplay of particle size and concentration effects
Published in International journal of pharmaceutics: X (01-06-2024)“…The contributions of fine excipient materials to drug dispersibility from carrier-based dry powder inhalation (DPI) formulations are well recognized, although…”
Get full text
Journal Article -
18
The Relationship Between the Permeability and the Performance of Carrier-Based Dry Powder Inhalation Mixtures: New Insights and Practical Guidance
Published in AAPS PharmSciTech (01-02-2018)“…The permeability of a powder bed reflects its particle size distribution, shape, packing, porosity, cohesivity, and tensile strength in a manner relevant to…”
Get full text
Journal Article -
19
Current Status of Brain Tumor in the Kingdom of Saudi Arabia and Application of Nanobiotechnology for Its Treatment: A Comprehensive Review
Published in Life (Basel, Switzerland) (05-05-2021)“…Brain tumors are the most challenging of all tumors and accounts for about 3% of all cancer allied deaths. The aim of the present review is to examine the…”
Get full text
Journal Article -
20
Lipid vesicles for skin delivery of drugs: Reviewing three decades of research
Published in International journal of pharmaceutics (06-03-2007)“…Since liposomes were first shown to be of potential value for topical therapy by Mezei and Gulasekharam in 1980, studies continued towards further…”
Get full text
Journal Article