Search Results - "Elsayed, Mahmoud M. A"
-
1
Synthesis, Physicochemical Characterization using a Facile Validated HPLC Quantitation Analysis Method of 4-Chloro-phenylcarbamoyl-methyl Ciprofloxacin and Its Biological Investigations
Published in International journal of molecular sciences (01-10-2023)“…A novel derivative of ciprofloxacin (Cpx) was synthesized and characterized using various analytical techniques, including FT-IR spectroscopy, UV-Vis…”
Get full text
Journal Article -
2
Tailoring of Rosuvastatin Calcium and Atenolol Bilayer Tablets for the Management of Hyperlipidemia Associated with Hypertension: A Preclinical Study
Published in Pharmaceutics (01-08-2022)“…Hyperlipidemia is still the leading cause of heart disease in patients with hypertension. The purpose of this study is to make rosuvastatin calcium (ROS) and…”
Get full text
Journal Article -
3
A Novel C@Fe@Cu Nanocomposite Loaded with Doxorubicin Tailored for the Treatment of Hepatocellular Carcinoma
Published in Pharmaceutics (01-09-2022)“…High mortality and morbidity rates are related to hepatocellular carcinoma (HCC), which is the most prevalent type of liver cancer. A new vision for cancer…”
Get full text
Journal Article -
4
Anti-Tumor Activity of Orally Administered Gefitinib-Loaded Nanosized Cubosomes against Colon Cancer
Published in Pharmaceutics (01-02-2023)“…Gefitinib (GFT) is a tyrosine kinase inhibitor drug used as a first-line treatment for patients with advanced or metastatic non-small cell lung, colon, and…”
Get full text
Journal Article -
5
Characterization and Bio-Evaluation of the Synergistic Effect of Simvastatin and Folic Acid as Wound Dressings on the Healing Process
Published in Pharmaceutics (01-10-2023)“…Wound healing is a significant healthcare problem that decreases the patient’s quality of life. Hence, several agents and approaches have been widely used to…”
Get full text
Journal Article -
6
Tailoring of Novel Azithromycin-Loaded Zinc Oxide Nanoparticles for Wound Healing
Published in Pharmaceutics (05-01-2022)“…Skin is the largest mechanical barrier against invading pathogens. Following skin injury, the healing process immediately starts to regenerate the damaged…”
Get full text
Journal Article -
7
Controlled release alginate-chitosan microspheres of tolmetin sodium prepared by internal gelation technique and characterized by response surface modeling
Published in Brazilian Journal of Pharmaceutical Sciences (01-01-2020)“…Tolmetin sodium (TS) is a powerful non-steroidal mitigating drug for the treatment of rheumatoid joint inflammation, osteoarthritis, and adolescent rheumatoid…”
Get full text
Journal Article -
8
Novel Green Biosynthesis of 5-Fluorouracil Chromium Nanoparticles Using Harpullia pendula Extract for Treatment of Colorectal Cancer
Published in Pharmaceutics (06-02-2021)“…Colorectal cancer (CRC) is the third highest major cause of morbidity and mortality worldwide. Hence, many strategies and approaches have been widely developed…”
Get full text
Journal Article -
9
Design and Optimization of Orally Administered Luteolin Nanoethosomes to Enhance Its Anti-Tumor Activity against Hepatocellular Carcinoma
Published in Pharmaceutics (02-05-2021)“…Luteolin (LUT) is a natural flavonoid with low oral bioavailability with restricted clinical applications due to its low solubility. LUT shows significant…”
Get full text
Journal Article -
10
Modified Spraying Technique and Response Surface Methodology for the Preparation and Optimization of Propolis Liposomes of Enhanced Anti-Proliferative Activity against Human Melanoma Cell Line A375
Published in Pharmaceutics (28-10-2019)“…Propolis is a honeybee product that contains a mixture of natural substances with a broad spectrum of biological activities. However, the clinical application…”
Get full text
Journal Article -
11
Tolmetin Sodium Fast Dissolving Tablets for Rheumatoid Arthritis Treatment: Preparation and Optimization Using Box-Behnken Design and Response Surface Methodology
Published in Pharmaceutics (18-04-2022)“…Tolmetin sodium (TLM) is a non-steroidal anti-inflammatory drug (NSAIDs). TLM is used to treat inflammation, skeletal muscle injuries, and discomfort…”
Get full text
Journal Article -
12
Multimodal modulation of hepatic ischemia/reperfusion-induced injury by phytochemical agents: A mechanistic evaluation of hepatoprotective potential and safety profiles
Published in International immunopharmacology (10-09-2024)“…•Ischemia reperfusion, linked to early/late graft rejection after liver transplant, liver failure after many liver surgeries.•Phytochemical agents exhibited…”
Get full text
Journal Article -
13
Clinical study on the efficacy of hepatitis B vaccination in hepatitis C virus related chronic liver diseases in Egypt
Published in Virus research (02-01-2023)“…•Chronic hepatitis B (HBV) and C virus (HCV) infections represent significant public health issues internationally•HCV infection and its complications…”
Get full text
Journal Article -
14
Development and optimization of vildagliptin solid lipid nanoparticles loaded ocuserts for controlled ocular delivery: A promising approach towards treating diabetic retinopathy
Published in International journal of pharmaceutics: X (01-06-2024)“…Diabetes mellitus (DM) is the most prevalent cause of diabetic retinopathy (DRP). DRP has been recognized for a long time as a microvascular disease. Many…”
Get full text
Journal Article -
15
Design And Characterisation Of Novel Sorafenib-Loaded Carbon Nanotubes With Distinct Tumour-Suppressive Activity In Hepatocellular Carcinoma
Published in International journal of nanomedicine (01-10-2019)“…Over the past 30 years, no consistent survival benefits have been recorded for anticancer agents of advanced hepatocellular carcinoma (HCC), except for the…”
Get full text
Journal Article -
16
Response Surface Methodology as a Useful Tool for Development and Optimization of Sustained Release Ketorolac Tromethamine Niosomal Organogels
Published in Journal of pharmaceutical innovation (01-12-2020)“…Purpose Niosomes as vesicular frameworks are novel methods of delivering a drug in a sustained manner to enhance its bioavailability and get therapeutic effect…”
Get full text
Journal Article