Search Results - "Elsayed, Ghada H."

Anti-proliferative activity, molecular genetics, docking analysis, and computational calculations of uracil cellulosic aldehyde derivatives by Fahim, Asmaa M., Dacrory, Sawsan, Elsayed, Ghada H.

“…In this study, the oxidation of microcrystalline cellulose using NaIO 4 to yield the corresponding cellulose aldehyde utilized microwave irradiation as a green…”
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Author Correction: Anti-proliferative activity, molecular genetics, docking analysis, and computational calculations of uracil cellulosic aldehyde derivatives by Fahim, Asmaa M., Dacrory, Sawsan, Elsayed, Ghada H.

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Chia Seed ( Salvia hispanica ) Attenuates Chemically Induced Lung Carcinomas in Rats through Suppression of Proliferation and Angiogenesis by Ali, Naglaa A, Elsayed, Ghada H, Mohamed, Safaa H, Abd Elkarim, Asmaa S, Aly, Mohamed S, Elgamal, Abdelbaset M, Elsayed, Wael M, El-Newary, Samah A

“…In 2022, 2.5 million cases of lung cancer were diagnosed, resulting in 1.8 million deaths. These statistics have motivated us to introduce a new natural…”
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In-vitro study of cytotoxic and apoptotic potential of Thalassia hemprichii (Ehren.) Asch. And Enhalus acoroides (L.f.) Royle against human breast cancer cell line (MCF-7) with correlation to their chemical profile by Mohamed, Shimaa I A, Elsayed, Ghada H, El Shaffai, Amgad, Yahya, Shaymaa M M, Mettwally, Walaa S A

“…Breast cancer is the most common type of cancer diagnosed in women. Finding novel therapeutic agents with significant cytotoxic action and minimal adverse…”
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Anti-proliferative action, molecular investigation and computational studies of novel fused heterocyclic cellulosic compounds on human cancer cells by Elsayed, Ghada H., Dacrory, Sawsan, Fahim, Asmaa M.

“…Reactivity of MCEC (3) with diazonium chloride, DMF-DMA and NH2NH2 to afford fused heterocyclic cellulosic derivative which confirmed through spectral…”
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The role of MiRNA-34 family in different signaling pathways and its therapeutic options by MM Yahya, Shaymaa, Elsayed, Ghada H.

“…•miRNAs are small noncoding RNA molecules.•miRNA were found to regulate many signaling pathways by regulating a massive number of genes at post-transcription…”
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Spectroscopic studies, DFT calculations, cytotoxicity activity, and docking stimulation of novel metal complexes of Schiff base ligand of isonicotinohydrazide derivative by Mahmoud, Nelly H., Elsayed, Ghada H., Aboelnaga, Asmaa, Fahim, Asmaa M.

“…In this elucidation, the reactivity of isonicotinohydrazide derivative (3)(L) was reacted with the nitrate salts of Cr(III), Fe(III), Co(II), Ni(II), Cu(II),…”
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Synthesis, antimicrobial, anti-proliferative activities, molecular docking and DFT studies of novel pyrazolo[5,1-c][1, 2, 4]triazine-3-carboxamide derivatives by Fahim, Asmaa M., Ismael, Eman H. I., Elsayed, Ghada H., Farag, Ahmad M.

“…In this investigation, we studied the reactivity of 5-aminouracil (1) with ethyl cyanoacetate (2) utilizing microwave irradiation to afford the corresponding…”
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Alginate sulfonamide hydrogel beads for 5-fluorouracil delivery: antitumor activity, cytotoxicity assessment, and theoretical investigation by Hashem, M.S., Sobh, Rokaya A., Fahim, Asmaa M., Elsayed, Ghada H.

“…This study focused on grafting a new monomer (E)-N-(4-(3-(4-bromophenyl) acryloyl) phenyl)-4-methyl benzene sulfonamide (Br-PS) onto sodium alginate (Alg)…”
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Restoring microRNA-34a overcomes acquired drug resistance and disease progression in human breast cancer cell lines via suppressing the ABCC1 gene by Yahya, Shaymaa M. M., Nabih, Heba K., Elsayed, Ghada H., Mohamed, Shimaa Ibrahim Abdelmenym, Elfiky, Asmaa M., Salem, Sohair M.

“…Purpose Breast cancer is one of the leading types of cancer diagnosed in women. Despite the improvements in chemotherapeutic cure strategies, drug resistance…”
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A summary for molecular regulations of miRNAs in breast cancer by Yahya, Shaymaa M.M., Elsayed, Ghada H.

“…Breast cancer is the most frequently diagnosed cancer and the leading cause of cancer-related death among women worldwide. MicroRNAs (miRNAs) are…”
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Design, Synthesis, Docking Studies and Biological Evaluation of Novel Benzochromenopyrimidines via Silica Sulfuric Acid Catalyzed Reaction on Apoptosis in Human Cancer Cells by Abdelazeem, Nagwa M., El-Hussieny, Marwa, El-Rashedy, Ahmed A., Elsayed, Ghada H.

“…Via one-pot reaction of 2-naphthol, thiobarbituric acid and aldehyde in the presence of silica sulfuric acid (SSA) as a catalyst to synthesis…”
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Synthesis and cytotoxic evaluation of novel hybrid estrane heterocycles as chemotherapeutic anti-cancer agents by Nada, Doaa S., Elkady, Dina S, Elsayed, Ghada H., A.-H. Abdel-Rahman, Adel, Elmegeed, Gamal A.

“…The effect of steroid derivatives on MCF7, PC3 and HepG2 cells. [Display omitted] •Novel class of hybrid estrane heterocyclic derivatives were synthesized and…”
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The effect of newly synthesized progesterone derivatives on apoptotic and angiogenic pathway in MCF-7 breast cancer cells by Yahya, Shaymaa M.M., Abdelhamid, Abdou O., Abd-Elhalim, Mervat M., Elsayed, Ghada H., Eskander, Emad F.

“…The effect of novel compounds on apoptotic and angiogenic gene expression levels in MCF-7 cells. [Display omitted] •This study introduced newly promising…”
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Evaluation of heterocyclic steroids and curcumin derivatives as anti-breast cancer agents: Studying the effect on apoptosis in MCF-7 breast cancer cells by Elmegeed, Gamal A., Yahya, Shaymaa M.M., Abd-Elhalim, Mervat M., Mohamed, Mervat S., Mohareb, Rafat M., Elsayed, Ghada H.

“…The present study aimed to introduce newly synthesized steroid and curcumin derivatives of promising anticancer effects. The pro-apoptotic effects of these…”
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Could miR-34a Inhibition be Used as a Tool to Overcome Drug Resistance in MCF-7 Cells Treated with Synthesized Steroidal Heterocycles? by Yahya, Shaymaa M M, Abd-Elhalim, Mervat M, Abdelhamid, Abdou O, Eskander, Emad F, Elsayed, Ghada H

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Cytotoxicity and gene expression profiles of novel synthesized steroid derivatives as chemotherapeutic anti-breast cancer agents by Elmegeed, Gamal A., Khalil, Wagdy K.B., Mohareb, Rafat M., Ahmed, Hanaa H., Abd-Elhalim, Mervat M., Elsayed, Ghada H.

“…The present study aimed to synthesize and evaluate new potential chemotherapeutic anti-breast cancer agents. Thiazolo-androstane 17 (IC50=2.5μM) exhibited more…”
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Investigating the role of miRNA-98 and miRNA-214 in chemoresistance of HepG2/Dox cells: studying their effects on predicted ABC transporters targets by Hamed, Ahmed R., Emara, Mohamed, Soltan, Maha M., Yahya, Shaymaa M. M., Nabih, Heba K., Elsayed, Ghada H.

“…Multidrug resistance (MDR) remains a burden in cancer chemotherapy. Several members of ATP-binding cassette (ABC transporters) are responsible for the efflux…”
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The Effect of Newly Synthesized Heterosteroids on miRNA34a, 98, and 214 Expression Levels in MCF-7 Breast Cancer Cells by Yahya, Shaymaa M. M., Elmegeed, Gamal A., Mohamed, Mervat S., Mohareb, Rafat M., Abd-Elhalim, Mervat M., Elsayed, Ghada H.

“…Hybrid anticancer drugs have emerged as great therapeutic options that can effectively overcome most obstacles facing conventional anticancer drugs. miRNAs are…”
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Synthesis, anti-cancer activity, gene expression and docking stimulation of 2-thioxoimidazolidin-4-one derivatives by Elsayed, Ghada H., Fahim, Asmaa M., Khodair, Ahmed I.

“…•Synthesis of 2-thioxoimidazolidin-4-one derivatives from N-methyl glycine and alkyl isothiocyanates.•Anti-tumor activities of 2-thioxoimidazolidin-4-one…”
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