Search Results - "Elsayed, G"
-
1
Megalin, a multi-ligand endocytic receptor, and its participation in renal function and diseases: A review
Published in Life sciences (1973) (01-11-2022)“…The endocytosis mechanism is a complicated system that is essential for cell signaling and survival. Megalin, a membrane-associated endocytic receptor, and its…”
Get full text
Journal Article -
2
miRNAs as cornerstones in adipogenesis and obesity
Published in Life sciences (1973) (15-02-2023)“…In recent decades, obesity has extensively emerged to the level of pandemics. It's significantly associated with serious co-morbidities that could decrease…”
Get full text
Journal Article -
3
miRNAs insights into rheumatoid arthritis: Favorable and detrimental aspects of key performers
Published in Life sciences (1973) (01-02-2023)“…Rheumatoid arthritis (RA) is a severe autoimmune inflammation that mostly affects the joints. It's a multifactorial disease. Its clinical picture depends on…”
Get full text
Journal Article -
4
Green Hydrogel-Biochar Composite for Enhanced Adsorption of Uranium
Published in ACS omega (21-12-2021)“…Uranium is the backbone of the nuclear fuel used for energy production but is still a hazardous environmental contaminant; thus, its removal and recovery are…”
Get full text
Journal Article -
5
Impact of the mother's gut microbiota on infant microbiome and brain development
Published in Neuroscience and biobehavioral reviews (01-07-2023)“…The link between the gut microbiome and health has recently garnered considerable interest in its employment for medicinal purposes. Since the early microbiota…”
Get full text
Journal Article -
6
An emphasis on the interaction of signaling pathways highlights the role of miRNAs in the etiology and treatment resistance of gastric cancer
Published in Life sciences (1973) (01-06-2023)“…Gastric cancer (GC) is 4th in incidence and mortality rates globally. Several genetic and epigenetic factors, including microRNAs (miRNAs), affect its…”
Get full text
Journal Article -
7
Discovery of pyrazolo[3,4-]pyrimidine and pyrazolo[4,3-][1,2,4]triazolo[1,5-]pyrimidine derivatives as novel CDK2 inhibitors: synthesis, biological and molecular modeling investigations
Published in RSC advances (17-05-2022)“…CDK2 inhibition is an appealing target for cancer treatment that targets tumor cells in a selective manner. A new set of small molecules featuring the…”
Get full text
Journal Article -
8
Beneficial and detrimental aspects of miRNAs as chief players in breast cancer: A comprehensive review
Published in International journal of biological macromolecules (01-01-2023)“…Breast cancer (BC) is the most common cancer in women and poses a serious threat to their health. Despite familiarity with factors affecting its etiology,…”
Get full text
Journal Article -
9
Improving the acoustic performance of flexible polyurethane foam using biochar modified by (3-aminopropyl)trimethoxysilane coupling agent
Published in Scientific reports (08-08-2024)“…This study aims to investigate the potential of integrating natural biochar (BC) derived from eggshell waste into flexible polyurethane (FPU) foam to enhance…”
Get full text
Journal Article -
10
From diagnosis to resistance: a symphony of miRNAs in pheochromocytoma progression and treatment response
Published in Naunyn-Schmiedeberg's archives of pharmacology (01-04-2024)“…Pheochromocytoma (PCC) is a neuroendocrine tumor that produces and secretes catecholamine from either the adrenal medulla or extra-adrenal locations. MicroRNAs…”
Get full text
Journal Article -
11
Androgen/androgen receptor affects gentamicin-induced nephrotoxicity through regulation of megalin expression
Published in Life sciences (1973) (15-06-2020)“…Investigation whether androgen/androgen receptor (AR) might regulate megalin expression and/or functionality and thus affecting Gentamicin-induced…”
Get full text
Journal Article -
12
Androgen receptor blockade by flutamide down-regulates renal fibrosis, inflammation, and apoptosis pathways in male rats
Published in Life sciences (1973) (15-06-2023)“…this study aims to explore the effect of androgen receptor (AR) blockade by flutamide on some renal pathologic changes such as inflammation, apoptosis, and…”
Get full text
Journal Article -
13
miRNAs role in glioblastoma pathogenesis and targeted therapy: Signaling pathways interplay
Published in Pathology, research and practice (01-06-2023)“…High mortality and morbidity rates and variable clinical behavior are hallmarks of glioblastoma (GBM), the most common and aggressive primary malignant brain…”
Get full text
Journal Article -
14
The role of miRNAs in ovarian cancer pathogenesis and therapeutic resistance – A focus on signaling pathways interplay
Published in Pathology, research and practice (01-12-2022)“…One of the most prevalent and lethal forms of gynecological cancer is ovarian cancer (OC), which is often diagnosed in its latter, deadly stages. The OC's high…”
Get full text
Journal Article -
15
Significance of miRNAs on the thyroid cancer progression and resistance to treatment with special attention to the role of cross-talk between signaling pathways
Published in Pathology, research and practice (01-03-2023)“…Thyroid cancer (TC) is the most prevalent endocrine malignant tumor. It has many types, the Papillary thyroid cancer (PTC)(most common and follicular thyroid…”
Get full text
Journal Article -
16
miRNAs as cornerstones in chronic lymphocytic leukemia pathogenesis and therapeutic resistance– An emphasis on the interaction of signaling pathways
Published in Pathology, research and practice (01-03-2023)“…Chronic lymphocytic leukemia (CLL) accounts for the vast majority of cases of leukemia. Patients of advanced age are more likely to develop the condition,…”
Get full text
Journal Article -
17
miRNAs as potential game-changers in head and neck cancer: Future clinical and medicinal uses
Published in Pathology, research and practice (01-05-2023)“…Head and neck cancers (HNCs) are a group of heterogeneous tumors formed most frequently from epithelial cells of the larynx, lips, oropharynx, nasopharynx, and…”
Get full text
Journal Article -
18
The interplay of signaling pathways with miRNAs in cholangiocarcinoma pathogenicity and targeted therapy
Published in Pathology, research and practice (01-05-2023)“…Cholangiocarcinoma (CCA), the second most frequent liver cancer after hepatocellular carcinoma, has been rising worldwide in recent epidemiological research…”
Get full text
Journal Article -
19
miRNAs as potential game-changers in melanoma: A comprehensive review
Published in Pathology, research and practice (01-04-2023)“…Melanoma is the sixth most frequent malignancy. It represents 1.7% of all cancer cases worldwide. Many risk factors are associated with melanoma including…”
Get full text
Journal Article -
20
miRNAs role in bladder cancer pathogenesis and targeted therapy: Signaling pathways interplay – A review
Published in Pathology, research and practice (01-02-2023)“…Bladder cancer (BC) is the 11th most popular cancer in females and 4th in males. A lot of efforts have been exerted to improve BC patients' care. Besides, new…”
Get full text
Journal Article