Search Results - "Elsayed, Ahmed K."

Circulating Non-Coding RNAs as a Signature of Autism Spectrum Disorder Symptomatology by Salloum-Asfar, Salam, Elsayed, Ahmed K., Elhag, Saba F., Abdulla, Sara A.

“…Autism spectrum disorder (ASD) is a multifaced neurodevelopmental disorder that becomes apparent during early childhood development. The complexity of ASD…”
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Keratinocytes Derived from Patient-Specific Induced Pluripotent Stem Cells Recapitulate the Genetic Signature of Psoriasis Disease by Ali, Gowher, Elsayed, Ahmed K, Nandakumar, Manjula, Bashir, Mohammed, Younis, Ihab, Abu Aqel, Yasmin, Memon, Bushra, Temanni, Ramzi, Abubaker, Fadhil, Taheri, Shahrad, Abdelalim, Essam M

“…Psoriasis is characterized by hyperproliferation and defective differentiation of keratinocytes (KCs). Patients with psoriasis are at a high risk of developing…”
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Genome-wide differential expression profiling of long non-coding RNAs in FOXA2 knockout iPSC-derived pancreatic cells by Elsayed, Ahmed K., Alajez, Nehad M., Abdelalim, Essam M.

“…Abstract Background Our recent studies have demonstrated the crucial involvement of FOXA2 in the development of human pancreas. Reduction of FOXA2 expression…”
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Aberrant development of pancreatic beta cells derived from human iPSCs with FOXA2 deficiency by Elsayed, Ahmed K., Younis, Ihab, Ali, Gowher, Hussain, Khalid, Abdelalim, Essam M.

“…FOXA2 has been identified as an essential factor for pancreas development and emerging evidence supports an association between FOXA2 and diabetes. Although…”
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Generation of nine induced pluripotent stem cell lines from six young children with autism spectrum disorder and three matched control subjects from the Qatari population by Ltaief, Samia M., Elsayed, Ahmed K., Al-Shammari, Abeer R.

“…Autism spectrum disorder (ASD) is a complex developmental disorder characterized by challenges with social interactions and restricted/repetitive behaviors…”
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Human induced pluripotent stem cell line (QBRIi013-A) derivation from a 6-year-old female diagnosed with Autism spectrum disorder (ASD) and intellectual disability (ID) by Elsayed, Ahmed K., Salloum-Asfar, Salam, Abdulla, Sara A.

“…Autism spectrum disorder (ASD) is a childhood-onset neurodevelopmental disorder characterized by social interaction, behavior, and communication challenges…”
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An induced pluripotent stem cell line derived from a patient with neonatal diabetes and Fanconi-Bickel syndrome caused by a homozygous mutation in the SLC2A2 gene by Elsayed, Ahmed K., Al-Khawaga, Sara, Hussain, Khalid, Abdelalim, Essam M.

“…Recessive mutations in the glucose transporter gene SLC2A2 (GLUT2) lead to permanent neonatal diabetes (PNDM) and Fanconi Bickel Syndrome (FBS). Here, we…”
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Differentiation of human pluripotent stem cells into two distinct NKX6.1 populations of pancreatic progenitors by Aigha, Idil I, Memon, Bushra, Elsayed, Ahmed K, Abdelalim, Essam M

“…The expression of a specific combination of transcription factors (TFs) in the multipotent progenitor cells (MPCs) is critical for determining pancreatic cell…”
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iPSCs derived from insulin resistant offspring of type 2 diabetic patients show increased oxidative stress and lactate secretion by Memon, Bushra, Elsayed, Ahmed K, Bettahi, Ilham, Suleiman, Noor, Younis, Ihab, Wehedy, Eman, Abou-Samra, Abdul Badi, Abdelalim, Essam M

“…Abstract Background The genetic factors associated with insulin resistance (IR) are not well understood. Clinical studies on first-degree relatives of type 2…”
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Derivation of a human induced pluripotent stem cell line (QBRIi007-A) from a patient carrying a homozygous intronic mutation (c.613-7T>G) in the SLC2A2 gene by Elsayed, Ahmed K., Aghadi, Maryam, Al-Khawaga, Sara, Hussain, Khalid, Abdelalim, Essam M.

“…Fanconi Bickel Syndrome (FBS) is an autosomal recessive disease resulting from mutations in the SLC2A2 gene, encoding the GLUT2. FBS patients develop diabetes…”
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Generation of a human induced pluripotent stem cell line (QBRIi009-A) from a patient with a heterozygous deletion of FOXA2 by Elsayed, Ahmed K., Aghadi, Maryam, Ali, Gowher, Al-Khawaga, Sara, Hussain, Khalid, Abdelalim, Essam M.

“…FOXA2 is a transcription factor, playing an important role during development. We established an induced pluripotent stem cell (iPSC) line, QBRIi009-A, using…”
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Generation of two human iPSC lines from patients with maturity-onset diabetes of the young type 2 (MODY2) and permanent neonatal diabetes due to mutations in the GCK gene by Aqel, Yasmin W. Abu, Ali, Gowher, Elsayed, Ahmed K., Al-Khawaga, Sara, Hussain, Khalid, Abdelalim, Essam M.

“…Heterozygous and homozygous mutations in the glucokinase (GCK) gene leads to maturity-onset diabetes of the young type 2 (MODY2) and permanent neonatal…”
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Deletion of RFX6 impairs iPSC-derived islet organoid development and survival, with no impact on PDX1 + /NKX6.1 + progenitors by Aldous, Noura, Elsayed, Ahmed K, Memon, Bushra, Ijaz, Sadaf, Hayat, Sikander, Abdelalim, Essam M

“…Homozygous mutations in RFX6 lead to neonatal diabetes accompanied by a hypoplastic pancreas, whereas heterozygous mutations cause MODY. Recent studies have…”
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Long-term exposure to p-Nitrophenol induces hepatotoxicity via accelerating apoptosis and glycogen accumulation in male Japanese quails by Ahmed, Eman A., Khaled, Howayda E., Elsayed, Ahmed K.

“…p -Nitrophenol (PNP) is the main end product of organophosphorus insecticides and a derivative of diesel exhaust particles. In addition to its unfavorable…”
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Identifying miRNA Signatures Associated with Pancreatic Islet Dysfunction in a FOXA2-Deficient iPSC Model by Elsayed, Ahmed K, Aldous, Noura, Alajez, Nehad M, Abdelalim, Essam M

“…The pathogenesis of diabetes involves complex changes in the expression profiles of mRNA and non-coding RNAs within pancreatic islet cells. Recent progress in…”
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iPSC-Derived Pancreatic Progenitors Lacking FOXA2 Reveal Alterations in miRNA Expression Targeting Key Pancreatic Genes by Aldous, Noura, Elsayed, Ahmed K, Alajez, Nehad M, Abdelalim, Essam M

“…Recently, we reported that forkhead box A2 (FOXA2) is required for the development of human pancreatic α- and β-cells. However, whether miRNAs play a role in…”
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Insulin resistance in diabetes: The promise of using induced pluripotent stem cell technology by Elsayed, Ahmed K, Vimalraj, Selvaraj, Nandakumar, Manjula, Abdelalim, Essam M

“…Insulin resistance (IR) is associated with several metabolic disorders, including type 2 diabetes (T2D). The development of IR in insulin target tissues…”
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Vesicles Stage of Camel Brain Development by Farouk, Sameh M, Hassan, Said A, Elsayed, Ahmed K, Abdo, Mohamed

“…A successive embryonic developmental study was conducted on the brain of twenty eight embryos and fetuses of one humped camel (Camelus Dromedarius), whose…”
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Vesicles Stage of Camel Brain Development/Etapas del Desarrollo de las Vesiculas Cerebrales del Camello by Farouk, Sameh M, Hassan, Said A, Elsayed, Ahmed K, Abdo, Mohamed

“…A successive embryonic developmental study was conducted on the brain of twenty eight embryos and fetuses of one humped camel (Camelus Dromedarius), whose…”
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