Search Results - "Elos, Mihret"

Mutations in the accessory subunit NDUFB10 result in isolated complex I deficiency and illustrate the critical role of intermembrane space import for complex I holoenzyme assembly by Friederich, Marisa W, Erdogan, Alican J, Coughlin, 2nd, Curtis R, Elos, Mihret T, Jiang, Hua, O'Rourke, Courtney P, Lovell, Mark A, Wartchow, Eric, Gowan, Katherine, Chatfield, Kathryn C, Chick, Wallace S, Spector, Elaine B, Van Hove, Johan L K, Riemer, Jan

“…An infant presented with fatal infantile lactic acidosis and cardiomyopathy, and was found to have profoundly decreased activity of respiratory chain complex I…”
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The innate immune system stimulating cytokine GM-CSF improves learning/memory and interneuron and astrocyte brain pathology in Dp16 Down syndrome mice and improves learning/memory in wild-type mice by Ahmed, Md. Mahiuddin, Wang, Athena Ching-Jung, Elos, Mihret, Chial, Heidi J., Sillau, Stefan, Solano, D. Adriana, Coughlan, Christina, Aghili, Leila, Anton, Paige, Markham, Neil, Adame, Vanesa, Gardiner, Katheleen J., Boyd, Timothy D., Potter, Huntington

“…Down syndrome (DS) is characterized by chronic neuroinflammation, peripheral inflammation, astrogliosis, imbalanced excitatory/inhibitory neuronal function,…”
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Chromosome Instability and Mosaic Aneuploidy in Neurodegenerative and Neurodevelopmental Disorders by Potter, Huntington, Chial, Heidi J, Caneus, Julbert, Elos, Mihret, Elder, Nina, Borysov, Sergiy, Granic, Antoneta

“…Evidence from multiple laboratories has accumulated to show that mosaic neuronal aneuploidy and consequent apoptosis characterizes and may underlie neuronal…”
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Interplay between Target Sequences and Repair Pathways Determines Distinct Outcomes of AID-Initiated Lesions by Chen, Zhangguo, Eder, Maxwell D, Elos, Mihret T, Viboolsittiseri, Sawanee S, Chen, Xiaomi, Wang, Jing H

“…Activation-induced deaminase (AID) functions by deaminating cytosines and causing U:G mismatches, a rate-limiting step of Ab gene diversification. However,…”
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AID-initiated DNA lesions are differentially processed in distinct B cell populations by Chen, Zhangguo, Ranganath, Sheila, Viboolsittiseri, Sawanee S, Eder, Maxwell D, Chen, Xiaomi, Elos, Mihret T, Yuan, Shunzong, Yuan, Shunzhong, Hansen, Erica, Wang, Jing H

“…Activation-induced deaminase (AID) initiates U:G mismatches, causing point mutations or DNA double-stranded breaks at Ig loci. How AID-initiated lesions are…”
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Functional Prostacyclin Synthase Promoter Polymorphisms: Impact in Pulmonary Arterial Hypertension by STEARMAN, Robert S, CORNELIUS, Amber R, COGAN, Joy D, PHILLIPS, John A, TAYLOR, Matthew R, GRAHAM, Brian B, TUDER, Rubin M, LOYD, James E, GERACI, Mark W, XIAO LU, CONKLIN, David S, DEL ROSARIO, Mark J, LOWE, Anita M, ELOS, Mihret T, FETTIG, Lynsey M, WONG, Randall E, HARA, Naoko

“…Pulmonary arterial hypertension (PAH) is a progressive disease characterized by elevated pulmonary artery pressure, vascular remodeling, and ultimately right…”
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Correction: AID-Initiated DNA Lesions Are Differentially Processed in Distinct B Cell Populations by Chen, Zhangguo, Ranganath, Sheila, Viboolsittiseri, Sawanee S, Eder, Maxwell D, Chen, Xiaomi, Elos, Mihret T, Yuan, Shunzong, Hansen, Erica, Wang, Jing H

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Combined deletion of Xrcc4 and Trp53 in mouse germinal center B cells leads to novel B cell lymphomas with clonal heterogeneity by Chen, Zhangguo, Elos, Mihret T, Viboolsittiseri, Sawanee S, Gowan, Katherine, Leach, Sonia M, Rice, Michael, Eder, Maxwell D, Jones, Kenneth, Wang, Jing H

“…Activated B lymphocytes harbor programmed DNA double-strand breaks (DSBs) initiated by activation-induced deaminase (AID) and repaired by non-homologous…”
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ELEVATED LEVELS OF MOSAIC ANEUPLOIDY IN HUNTINGTON’S DISEASE by Caneus, Julbert, Elos, Mihret, Potter, Huntington

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P1‐213: ELEVATED LEVELS OF MOSAIC ANEUPLOIDY IN HUNTINGTON'S DISEASE by Caneus, Julbert, Elos, Mihret, Potter, Huntington

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GM‐CSF Treatment Increases the Number of Purkinje Cells in a Mouse Model of Down Syndrome by Ahmed, Md. Mahiuddin, Aghili, Leila, Wang, Athena Ching‐Jung, Elos, Mihret, Boyd, Timothy D., Chial, Heidi J, Potter, Huntington

“…Background Down syndrome (DS), the most common chromosomal disorder that is a genetic cause of intellectual disability (ID), is characterized by mild‐to‐severe…”
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Elevated levels of mosaic aneuploidy in brain cells and fibroblast cell lines from human Huntington’s disease donors and in brain cells from Huntington’s disease mouse models by Elos, Mihret, Caneus, Julbert, Ahmed, Md. Mahiuddin, Grissom, Paula M., Markham, Neil, Johnson, Noah R, Chial, Heidi J, Potter, Huntington

“…Background Huntington’s disease (HD) is a progressive neurodegenerative disorder that presents with motor and cognitive deficits and psychiatric disturbances…”
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Role of mosaic aneuploidy in the development and progression of Huntington's disease by Elos, Mihret, Caneus, Julbert, Ahmed, Md Mahiuddin, Markham, Neil, Chial, Heidi J, Potter, Huntington

“…Background Huntington disease (HD) is an autosomal dominant neurodegenerative disorder caused by a CAG trinucleotide repeat expansion mutation in the…”
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Role of mosaic aneuploidy in the development and progression of Huntington's disease: Developing topics by Elos, Mihret, Caneus, Julbert, Ahmed, Md Mahiuddin, Markham, Neil, Chial, Heidi J, Potter, Huntington

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GM-CSF REVERSES MEMORY DEFICITS IN THE DP16 MOUSE MODEL OF DOWN SYNDROME by Ahmed, Md. Mahiuddin, Jung Wang, Athena Ching, Boyd, Timothy, Elos, Mihret, Gardiner, Katheleen J., Potter, Huntington

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P2‐162: GM‐CSF REVERSES MEMORY DEFICITS IN THE DP16 MOUSE MODEL OF DOWN SYNDROME by Ahmed, Md. Mahiuddin, Jung Wang, Athena Ching, Boyd, Timothy, Elos, Mihret, Gardiner, Katheleen J., Potter, Huntington

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GM-CSF REVERSES MEMORY DEFICITS IN NORMAL AGED MICE AND IN THE DP(16)1YEY MOUSE MODEL OF DOWN SYNDROME by Ahmed, Md. Mahiuddin, Jung Wang, Athena Ching, Boyd, Timothy, Elos, Mihret, Chial, Heidi J., Gardiner, Katheleen J., Potter, Huntington

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P4‐032: GM‐CSF REVERSES MEMORY DEFICITS IN NORMAL AGED MICE AND IN THE DP(16)1YEY MOUSE MODEL OF DOWN SYNDROME by Ahmed, Md. Mahiuddin, Jung Wang, Athena Ching, Boyd, Timothy, Elos, Mihret, Chial, Heidi J., Gardiner, Katheleen J., Potter, Huntington

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AID-initiated DNA lesions are differentially processed in distinct B cell populations (IRM8P.701) by Wang, Jing, Chen, Zhangguo, Ranganath, Sheila, Viboolsittiseri, Sawanee, Eder, Maxwell, Elos, Mihret, Chen, Xiaomi, Hansen, Erica

“…Activation-induced deaminase (AID) initiates U:G mismatches, causing point mutations or DNA double-stranded breaks at immunoglobulin (Ig) loci. How…”
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AID-Initiated DNA Lesions Are Differentially Processed in Distinct B cell Populations1 by Chen, Zhangguo, Ranganath, Sheila, Viboolsittiseri, Sawanee S., Eder, Maxwell D., Chen, Xiaomi, Elos, Mihret T., Yuan, Shunzhong, Hansen, Erica, Wang, Jing H.

“…Activation-induced deaminase (AID) initiates U:G mismatches, causing point mutations or DNA double-stranded breaks at immunoglobulin ( Ig ) loci. How…”
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