Search Results - "Elorza, A"

Role of Copper on Mitochondrial Function and Metabolism by Ruiz, Lina M., Libedinsky, Allan, Elorza, Alvaro A.

“…Copper is essential for life processes like energy metabolism, reactive oxygen species detoxification, iron uptake, and signaling in eukaryotic organisms…”
Get full text

High throughput microplate respiratory measurements using minimal quantities of isolated mitochondria by Rogers, George W, Brand, Martin D, Petrosyan, Susanna, Ashok, Deepthi, Elorza, Alvaro A, Ferrick, David A, Murphy, Anne N

“…Recently developed technologies have enabled multi-well measurement of O(2) consumption, facilitating the rate of mitochondrial research, particularly…”
Get full text

Photoexcitation cascade and multiple hot-carrier generation in graphene by Tielrooij, K. J., Song, J. C. W., Jensen, S. A., Centeno, A., Pesquera, A., Zurutuza Elorza, A., Bonn, M., Levitov, L. S., Koppens, F. H. L.

“…The conversion of light into free electron–hole pairs constitutes the key process in the fields of photodetection and photovoltaics. The efficiency of this…”
Get full text

Role of Oxidative Stress as Key Regulator of Muscle Wasting during Cachexia by Cabello-Verrugio, Claudio, Cabrera, Daniel, Simon, F., Vilos, Cristian, Riedel, C. A., Elorza, Alvaro A., Abrigo, Johanna, Estrada, Lisbell

“…Skeletal muscle atrophy is a pathological condition mainly characterized by a loss of muscular mass and the contractile capacity of the skeletal muscle as a…”
Get full text

Biomarkers in Thyroid Cancer: Emerging Opportunities from Non-Coding RNAs and Mitochondrial Space by Cabané, Patricio, Correa, Claudio, Bode, Ignacio, Aguilar, Rodrigo, Elorza, Alvaro A

“…Thyroid cancer diagnosis primarily relies on imaging techniques and cytological analyses. In cases where the diagnosis is uncertain, the quantification of…”
Get full text

mtDNA Heteroplasmy at the Core of Aging-Associated Heart Failure. An Integrative View of OXPHOS and Mitochondrial Life Cycle in Cardiac Mitochondrial Physiology by Elorza, Alvaro A, Soffia, Juan Pablo

“…The most common aging-associated diseases are cardiovascular diseases which affect 40% of elderly people. Elderly people are prone to suffer aging-associated…”
Get full text

Erythropoietin induces bone marrow and plasma fibroblast growth factor 23 during acute kidney injury by Toro, Luis, Barrientos, Víctor, León, Pablo, Rojas, Macarena, Gonzalez, Magdalena, González-Ibáñez, Alvaro, Illanes, Sebastián, Sugikawa, Keigo, Abarzúa, Néstor, Bascuñán, César, Arcos, Katherine, Fuentealba, Carlos, Tong, Ana María, Elorza, Alvaro A, Pinto, María Eugenia, Alzamora, Rodrigo, Romero, Carlos, Michea, Luis

“…It is accepted that osteoblasts/osteocytes are the major source for circulating fibroblast growth factor 23 (FGF23). However, erythropoietic cells of bone…”
Get more information

Dynamic Distribution of HIG2A between the Mitochondria and the Nucleus in Response to Hypoxia and Oxidative Stress by Salazar, Celia, Barros, Miriam, Elorza, Alvaro A, Ruiz, Lina María

“…Mitochondrial respiratory supercomplex formation requires HIG2A protein, which also has been associated with cell proliferation and cell survival under…”
Get full text

The OXPHOS supercomplex assembly factor HIG2A responds to changes in energetic metabolism and cell cycle by Salazar, Celia, Elorza, Alvaro A., Cofre, Glenda, Ruiz‐Hincapie, Paula, Shirihai, Orian, Ruiz, Lina María

“…HIG2A promotes cell survival under hypoxia and mediates the assembly of complex III and complex IV into respiratory chain supercomplexes. In the present study,…”
Get full text

Cytosolic NUAK1 Enhances ATP Production by Maintaining Proper Glycolysis and Mitochondrial Function in Cancer Cells by Escalona, Emilia, Muñoz, Marcelo, Pincheira, Roxana, Elorza, Álvaro A., Castro, Ariel F.

“…NUAK1 is an AMPK-related kinase located in the cytosol and the nucleus, whose expression associates with tumor malignancy and poor patient prognosis in several…”
Get full text

Sarcopenia Induced by Chronic Liver Disease in Mice Requires the Expression of the Bile Acids Membrane Receptor TGR5 by Abrigo, Johanna, Campos, Fabián, Gonzalez, Francisco, Aguirre, Francisco, Gonzalez, Andrea, Huerta-Salgado, Camila, Conejeros, Sabrina, Simon, Felipe, Arrese, Marco, Cabrera, Daniel, Elorza, Alvaro A, Cabello-Verrugio, Claudio

“…Sarcopenia is a condition of muscle dysfunction, commonly associated with chronic liver disease (CLD), characterized by a decline in muscle strength, the…”
Get full text

Cholic and deoxycholic acids induce mitochondrial dysfunction, impaired biogenesis and autophagic flux in skeletal muscle cells by Abrigo, Johanna, Olguín, Hugo, Tacchi, Franco, Orozco-Aguilar, Josué, Valero-Breton, Mayalen, Soto, Jorge, Castro-Sepúlveda, Mauricio, Elorza, Alvaro A, Simon, Felipe, Cabello-Verrugio, Claudio

“…Skeletal muscle is sensitive to bile acids (BA) because it expresses the TGR5 receptor for BA. Cholic (CA) and deoxycholic (DCA) acids induce a sarcopenia-like…”
Get full text

The mitochondrial transporter ABC-me (ABCB10), a downstream target of GATA-1, is essential for erythropoiesis in vivo by Hyde, B B, Liesa, M, Elorza, A A, Qiu, W, Haigh, S E, Richey, L, Mikkola, H K, Schlaeger, T M, Shirihai, O S

“…The mitochondrial transporter ATP binding cassette mitochondrial erythroid (ABC-me/ABCB10) is highly induced during erythroid differentiation by GATA-1 and its…”
Get full text

Image-based face beauty analysis via graph-based semi-supervised learning by Dornaika, F., Elorza, A., Wang, K., Arganda-Carreras, I.

“…Automatic facial beauty analysis has become an emerging research topic. Despite some achieved advances, current methods and systems suffer from at least two…”
Get full text

Administration of Secretome Derived from Human Mesenchymal Stem Cells Induces Hepatoprotective Effects in Models of Idiosyncratic Drug-Induced Liver Injury Caused by Amiodarone or Tamoxifen by Huang, Ya-Lin, De Gregorio, Cristian, Silva, Verónica, Elorza, Álvaro A, Léniz, Patricio, Aliaga-Tobar, Víctor, Maracaja-Coutinho, Vinicius, Budini, Mauricio, Ezquer, Fernando, Ezquer, Marcelo

“…Drug-induced liver injury (DILI) is one of the leading causes of acute liver injury. While many factors may contribute to the susceptibility to DILI, obese…”
Get full text

The mitochondrial protease ClpP is a druggable target that controls VSMC phenotype by a SIRT1-dependent mechanism by Paredes, Felipe, Williams, Holly C., Liu, Xuesong, Holden, Claire, Bogan, Bethany, Wang, Yu, Crotty, Kathryn M., Yeligar, Samantha M., Elorza, Alvaro A., Lin, Zhiyong, Rezvan, Amir, San Martin, Alejandra

“…Vascular smooth muscle cells (VSMCs), known for their remarkable lifelong phenotypic plasticity, play a pivotal role in vascular pathologies through their…”
Get full text

Lipopolysaccharide induces a fibrotic‐like phenotype in endothelial cells by Echeverría, César, Montorfano, Ignacio, Sarmiento, Daniela, Becerra, Alvaro, Nuñez‐Villena, Felipe, Figueroa, Xavier F., Cabello‐Verrugio, Claudio, Elorza, Alvaro A., Riedel, Claudia, Simon, Felipe

“…Endothelial dysfunction is crucial in endotoxaemia‐derived sepsis syndrome pathogenesis. It is well accepted that lipopolysaccharide (LPS) induces endothelial…”
Get full text

Nutritional status modulates plasma leptin, AMPK and TOR activation, and mitochondrial biogenesis: Implications for cell metabolism and growth in skeletal muscle of the fine flounder by Fuentes, Eduardo N, Safian, Diego, Einarsdottir, Ingibjörg Eir, Valdés, Juan Antonio, Elorza, Alvaro A, Molina, Alfredo, Björnsson, Björn Thrandur

“…Graphical abstract Highlights ► Study showing novel data on fish skeletal muscle growth and metabolism. ► Positive relationship between plasma leptin and AMPK…”
Get full text

Bile Acids Induce Alterations in Mitochondrial Function in Skeletal Muscle Fibers by Abrigo, Johanna, Olguín, Hugo, Gutierrez, Danae, Tacchi, Franco, Arrese, Marco, Cabrera, Daniel, Valero-Breton, Mayalen, Elorza, Alvaro A, Simon, Felipe, Cabello-Verrugio, Claudio

“…Cholestatic chronic liver disease is characterized by developing sarcopenia and elevated serum levels of bile acids. Sarcopenia is a skeletal muscle disorder…”
Get full text

CD73 Ectonucleotidase Restrains CD8+ T Cell Metabolic Fitness and Anti-tumoral Activity by Briceño, Pedro, Rivas-Yañez, Elizabeth, Rosemblatt, Mariana V, Parra-Tello, Brian, Farías, Paula, Vargas, Leonardo, Simon, Valeska, Cárdenas, César, Lladser, Alvaro, Salazar-Onfray, Flavio, Elorza, Alvaro A, Rosemblatt, Mario, Bono, María Rosa, Sauma, Daniela

“…CD39 and CD73 are ectoenzymes that dephosphorylate ATP into its metabolites; ADP, AMP, and adenosine, and thus are considered instrumental in the development…”
Get full text