Search Results - "Eloranta, T O"

1-Aminooxy-3-aminopropane reversibly prevents the proliferation of cultured baby hamster kidney cells by interfering with polyamine synthesis by Hyvönen, T, Alakuijala, L, Andersson, L, Khomutov, A R, Khomutov, R M, Eloranta, T O

“…The effects on cultured baby hamster kidney cells of 1-aminooxy-3-aminopropane, a potent new inhibitor of mammalian ornithine and S-adenosylmethionine…”
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Differential effects of sepsis and trauma on urinary excretion of polyamines by Pöyhönen, M J, Takala, J A, Pitkänen, O, Kari, A, Alakuijala, L A, Eloranta, T O

“…Urinary excretion of polyamines increases in patients with trauma and infection. To separate the effect of infection from the general metabolic response to…”
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Adaptation of adenosylmethionine metabolism and methionine recycling to variations in dietary methionine in the rat by Eloranta, T O, Martikainen, V, Smith, T K

“…Weanling rats were fed a casein-based diet supplemented to give dietary methionine (Met) concentrations of 0.41, 0.61, and 1.50%. After 2 weeks of feeding, the…”
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Tissue distribution of S-adenosylmethionine and S-adenosylhomocysteine in the rat. Effect of age, sex and methionine administration on the metabolism of S-adenosylmethionine, S-adenosylhomocysteine and polyamines by Eloranta, T O

“…The tissue distribution of S-adenosylmethionine, S-adenosylhomocysteine, methionine adenosyltransferase and S-adenosylhomocysteine hydrolase was explored in…”
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Mapping of the human spermidine synthase gene (SRM) to 1p36 and a probable pseudogene (SRML2) to region 3p14-->q21 by Winqvist, R, Alhonen, L, Grzeschik, K H, Jänne, J, Eloranta, T O

“…Using Southern blot analysis of panels of human podent somatic cell hybrids and chromosomal in situ hybridization, we have been able to assign human spermidine…”
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Metabolism, cellular actions, and cytotoxicity of selenomethionine in cultured cells by KAJANDER, E. O, HARVIMA, R. J, ELORANTA, T. O, MARTIKAINEN, H, KANTOLA, M, KAÊRENLAMPI, S. O, AKERMAN, K

“…Selenomethionine metabolism and the biochemical basis for its cytotoxicity were analyzed in cultured human and murine lymphoid cells. The metabolic pathways…”
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Catabolism and lability of S-adenosyl-L-methionine in rat liver extracts by Eloranta, T O, Kajander, E O

“…The fate of S-adenosyl-L-methionine was studied in rat liver extracts by analysing the distribution of radioactivity from labelled adenosylmethionine in…”
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Polyamine Excretion in Depleted Patients With Gastrointestinal Malignancy: Effect of Perioperative Nutrition and Tumor Removal by Pöyhönen, Mikko J., Takala, Jukka A., Pitkänen, Otto, Kari, Aarno, Alhava, Esko, Alakuijala, Lsa A., Eloranta, Terho O.

“…Polyamines, synthesized by all mammalian cells, are involved in protein and energy metabolism. We measured urinary excretion of polyamines, putrescine,…”
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Purification and partial characterization of human polyamine synthases by Kajander, E O, Kauppinen, L I, Pajula, R L, Karkola, K, Eloranta, T O

“…Spermidine synthase was purified to apparent homogeneity from human spleens (8700-fold) by affinity chromatography. The native enzyme was composed of two…”
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Synthesis and analysis of selenomethionine metabolites by Kajander, E O, Pajula, R L, Harvima, R J, Eloranta, T O

“…This paper describes the enzymatic synthesis of selenomethionine metabolites of the transmethylation and polyamine synthesis pathways:…”
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Urinary excretion of polyamines: importance of circadian rhythm, age, sex, menstrual cycle, weight, and creatinine excretion by Pöyhönen, MJ, Uusitalo, UM, Kari, A, Takala, JA, Alakuijala, LA, Eloranta, TO

“…The urinary excretion of putrescine, spermidine, spermine, and N1- and N8-acetylspermidines was measured in 95 volunteers. The 24-h excretion, split in four…”
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Application of oxime formation in a radiometric assay of aminooxy compounds by Keinänen, T A, Hyvönen, T, Khomutov, A R, Khomutov, R M, Kauppinen, R A, Vepsäläinen, J, Eloranta, T O

“…A radiometric determination of monoaminooxy analogues of naturally occurring polyamines is described in which [2-14C]acetone is employed as reagent. The…”
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Polyamines may regulate S-phase progression but not the dynamic changes of chromatin during the cell cycle by Laitinen, Jens, Stenius, Katinka, Eloranta, Terho O., Hölttä, Erkki

“…Several studies suggest that polyamines may stabilize chromatin and play a role in its structural alterations. In line with this idea, we found here by…”
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Effect of human mast cell tryptase on human plasma proenzymes by Harvima, I T, Harvima, R J, Penttilä, I M, Eloranta, T O, Horsmanheimo, M, Fräki, J E

“…The effect of human skin mast cell tryptase on human plasma proenzymes (prothrombin, coagulation factor XII, complement C1s, protein C and plasminogen) was…”
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Effects of dietary polyamine precursors on the metabolism and tissue concentrations of amino acids in the rat by Smith, T K, Lindqvist, L, Alakuijala, L, Eloranta, T O

“…Experiments were conducted to determine the effects of dietary supplements of amino acid precursors of polyamines on amino acid metabolism in the rat in order…”
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S-adenosylmethionine metabolism and its relation to polyamine synthesis in rat liver. Effect of nutritional state, adrenal function, some drugs and partial hepatectomy by Eloranta, T O, Raina, A M

“…S-Adenosylmethionine metabolism and its relation to the synthesis and accumulation of polyamines was studied in rat liver under various nutritional conditions,…”
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Uptake and utilization of 5'-methylthioadenosine by cultured baby-hamster kidney cells by Eloranta, T O, Tuomi, K, Raina, A M

“…5'-Methylthioadenosine was taken up and immediately metabolized further by cultured baby-hamster kidney cells during the exponential phase of growth. The…”
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Methionine toxicity in the rat in relation to hepatic accumulation of S-adenosylmethionine: prevention by dietary stimulation of the hepatic transsulfuration pathway by Regina, M, Korhonen, V P, Smith, T K, Alakuijala, L, Eloranta, T O

“…Rats were fed toxic levels of methionine with or without simultaneous dietary supplements of glycine and serine. Feed intake, growth rate, and metabolite…”
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Effect of dietary methionine, arginine and ornithine on the metabolism and accumulation of polyamines, S-adenosylmethionine and macromolecules in rat liver and skeletal muscle by Smith, T K, Hyvönen, T, Pajula, R L, Eloranta, T O

“…The interrelationship and possible causality of polyamine synthesis and the transmethylation pathway in the growth-retarding effects of inadequate or excess…”
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Monitoring of the uptake and metabolism of aminooxy analogues of polyamines in cultured cells by high-performance liquid chromatography by Hyvönen, T, Keinänen, T A, Khomutov, A R, Khomutov, R M, Eloranta, T O

“…A high-performance liquid chromatographic method for the determination of polyamines and their aminooxy analogues is described. Oxime derivatization with a…”
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