Search Results - "Elner, VM"

Interleukin-8 as a Macrophage-Derived Mediator of Angiogenesis by Koch, Alisa E., Polverini, Peter J., Kunkel, Steven L., Harlow, Lisa A., DiPietro, Luisa A., Elner, Victor M., Elner, Susan G., Strieter, Robert M.

“…Angiogenic factors produced by monocytes-macrophages are involved in the pathogenesis of chronic inflammatory disorders characterized by persistent…”
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Macrophage and retinal pigment epithelium expression of angiogenic cytokines in choroidal neovascularization by Grossniklaus, Hans E, Ling, Jun X, Wallace, Timothy M, Dithmar, Stefan, Lawson, Diane H, Cohen, Cynthia, Elner, Victor M, Elner, Susan G, Sternberg, Jr, Paul

“…To determine the expression of angiogenic cytokines in macrophages and retinal pigment epithelium cells in choroidal neovascularization (CNV). Ten…”
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Toll-like receptor 4 variant D299G is associated with susceptibility to age-related macular degeneration by Zareparsi, Sepideh, Buraczynska, Monika, Branham, Kari E.H., Shah, Sapna, Eng, Donna, Li, Mingyao, Pawar, Hemant, Yashar, Beverly M., Moroi, Sayoko E., Lichter, Paul R., Petty, Howard R., Richards, Julia E., Abecasis, Gonçalo R., Elner, Victor M., Swaroop, Anand

“…Age-related macular degeneration (AMD) is a genetically heterogeneous disease that leads to progressive and irreversible vision loss among the elderly…”
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Intercellular adhesion molecule-1 in human corneal endothelium. Modulation and function by Elner, VM, Elner, SG, Pavilack, MA, Todd, RF, 3d, Yue, BY, Huber, AR

“…The endothelium lining the posterior corneal surface performs physiologic pump functions essential to corneal clarity and integrity. A hallmark of keratitis,…”
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Role of MCP-1 and MIP-1α in retinal neovascularization during postischemic inflammation in a mouse model of retinal neovascularization by Yoshida, Shigeo, Yoshida, Ayako, Ishibashi, Tatsuro, Elner, Susan G., Elner, Victor M.

“…Macrophages are important participants in neovascularization. This study was designed to examine the role of the monocyte/macrophage chemotactic proteins,…”
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Intercellular adhesion molecule-1 mediates to expression of monocyte-derived MIP-1α during monocyte-endothelial cell interactions by LUKACS, N. W, STRIETER, R. M, ELNER, V. M, EVANOFF, H. L, BURDICK, M, KUNKEL, S. L

“…The extravasation of leukocytes from the lumen of the vessel to a site of inflammation initially requires a specific binding event followed by migration of the…”
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Gene expression profile of human trabecular meshwork cells in response to long-term dexamethasone exposure by Rozsa, Frank W, Reed, David M, Scott, Kathleen M, Pawar, Hemant, Moroi, Sayoko E, Kijek, Theresa Guckian, Krafchak, Charles M, Othman, Mohammad I, Vollrath, Douglas, Elner, Victor M, Richards, Julia E

“…Topical use of dexamethasone has long been associated with steroid induced-glaucoma, although the mechanism is unknown. We applied a strict filtering of…”
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Toll-like receptor 4 (TLR4) of retinal pigment epithelial cells participates in transmembrane signaling in response to photoreceptor outer segments by Kindzelskii, Andrei L, Elner, Victor M, Elner, Susan G, Yang, Dongli, Hughes, Bret A, Petty, Howard R

“…Retinal pigment epithelial (RPE) cells mediate the recognition and clearance of effete photoreceptor outer segments (POS), a process central to the maintenance…”
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Differential Involvement of Phosphoinositide 3-Kinase/Akt in Human RPE MCP-1 and IL-8 Expression by Bian, Zong-Mei, Elner, Susan G, Yoshida, Ayako, Elner, Victor M

“…To investigate the role of the phosphatidylinositol 3-kinase (PI3K) pathway and the signal mediator AP-1 in monocyte chemotactic protein (MCP)-1 and…”
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Local corticosteroid treatment of eyelid and orbital xanthogranuloma by Elner, Victor M, Mintz, Roni, Demirci, Hakan, Hassan, Adam S

“…To demonstrate the efficacy of local corticosteroid therapy for the treatment of eyelid and orbital xanthogranuloma in adults. The authors performed a…”
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Human RPE-monocyte co-culture induces chemokine gene expression through activation of MAPK and NIK cascade by Bian, Zong-Mei, Elner, Susan G., Yoshida, Ayako, Elner, Victor M.

“…Cell–cell contact between human retinal pigment epithelium (hRPE) cells and monocytes occurs in many retinal diseases involving blood-retinal barrier…”
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TLR4 Mediates Human Retinal Pigment Epithelial Endotoxin Binding and Cytokine Expression by Elner, Susan G, Petty, Howard R, Elner, Victor M, Yoshida, Ayako, Bian, Zong-Mei, Yang, Dongli, Kindzelskii, Andrei L

“…It was previously demonstrated that toll-like receptor 4 (TLR4) is involved in species-specific human retinal pigment epithelial (HRPE) photoreceptor outer…”
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Atopy: a patient-specific risk factor for diffuse lamellar keratitis by Boorstein, Stephen M, Henk, Henry J, Elner, Victor M

“…To identify whether atopy is a patient-specific risk factor for the development of diffuse lamellar keratitis (DLK) after laser in situ keratomileusis (LASIK)…”
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Lacrimal gland involvement in graft-versus-host disease : A murine model by HASSAN, Adam S, CLOUTHIER, Shown G, FERRARA, James L. M, STEPAN, Alexandra, MIAN, Shahzad I, AHMAD, Amjad Z, ELNER, Victor M

“…To describe lacrimal gland involvement in a murine model of acute graft-versus-host disease (GVHD). Histopathologic examination was performed on lacrimal…”
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Ex vivo produced human conjunctiva and oral mucosa equivalents grown in a serum-free culture system by Yoshizawa, Michiko, Feinberg, Stephen E, Marcelo, Cynthia L, Elner, Victor M

“…We sought to develop full-thickness ex vivo produced human conjunctiva and oral mucosa equivalents using a serum-free culture system without a feeder layer and…”
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Activation of p38, ERK1/2 and NIK Pathways is Required for IL-1β and TNF-α-induced Chemokine Expression in Human Retinal Pigment Epithelial Cells by Bian, Zong-Mei, Elner, Susan G, Yoshida, Ayako, Kunkel, Steven L, Su, Jia, Elner, Victor M

“…Chemokine secretion by human retinal pigment epithelium (hRPE) in response to IL-1β and TNF-α occurs in infectious and noninfectious retinal diseases. In this…”
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Signaling Pathways for Glycated Human Serum Albumin-Induced IL-8 and MCP-1 Secretion in Human RPE Cells by Bian, Zong-Mei, Elner, Victor M, Yoshida, Ayako, Kunkel, Steven L, Elner, Susan G

“…To determine the signal mediators involved in glycated human serum albumin (GHSA) stimulation of interleukin (IL)-8 and monocyte chemotactic protein (MCP)-1…”
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Interleukin-8. A corneal factor that induces neovascularization by Strieter, RM, Kunkel, SL, Elner, VM, Martonyi, CL, Koch, AE, Polverini, PJ, Elner, SG

“…A rabbit corneal pocket model was used to demonstrate that physiologic concentrations of human recombinant (r) IL-8 may induce corneal neovascularization…”
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Cytokines in proliferative diabetic retinopathy and proliferative vitreoretinopathy by Elner, S G, Elner, V M, Jaffe, G J, Stuart, A, Kunkel, S L, Strieter, R M

“…We determined whether interleukin-8, monocyte chemotactic protein-1, and macrophage-colony stimulating factor are present in the vitreous of patients with…”
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The integrin superfamily and the eye by Elner, SG, Elner, VM

“…Integrins may have many different roles in the eye, from influencing ocular development, cell migration in wound healing or pathologic processes, and…”
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