Search Results - "Elnaggar, Dina H."
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5-Chlorobenzofuran-2-carboxamides: From allosteric CB1 modulators to potential apoptotic antitumor agents
Published in European journal of medicinal chemistry (01-09-2019)“…Cannabinoids as THC and the CB1 allosteric modulator CBD were reported to have antiproliferative activities with no reports for other CB1 allosteric modulators…”
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Synthesis, Antimicrobial and Antitumor Evaluations of a New Class of Thiazoles Substituted on the Chromene Scaffold
Published in Mini reviews in medicinal chemistry (01-01-2019)“…A new series of thiazoles substituted on the chromene scaffold were prepared by facial approaches starting from…”
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Antiproliferative Activity of Some Newly Synthesized Substituted Nicotinamides Candidates Using Pyridine-2(1H) thione Derivatives as Synthon
Published in ACS omega (29-03-2022)“…Some new pyridinethione and thienopyridine derivatives have been synthesized and evaluated for their antiproliferative activity using the MTT assay…”
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Synthesis, Characterization, and Cytotoxic Evaluation of Some Newly Substituted Diazene Candidates
Published in Journal of chemistry (01-01-2018)“…A series of azocompounds containing methyl salicylate 4a–k and 1-naphthyl moiety 6–8 was synthesized and tested as anticancer agents. Nitrosation of methyl…”
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Synthesis, Anticancer Activity, Pharmacokinetics, and Docking Study of Some New Heterocycles Linked Indole Moiety
Published in Polycyclic aromatic compounds (26-11-2023)“…A novel series of five or six new nitrogenated heterocyclic compounds were obtained by reacting a chalcone derivative of 3-acetylindole with various reagents…”
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Novel [1,2,3]triazoles, [1,2,3]triazolo[4,5-d]Pyrimidines, and Some of Their Glycoside Derivatives: Synthesis and Molecular Modeling as Potential Apoptotic Antitumor Agents
Published in Polycyclic aromatic compounds (15-03-2024)“…Two new series of 4,5-difunctionalized 1-bromobenzyl[1,2,3]triazole (2a, 3a, 4a, 5a, and 6a) and 4,5-difunctionalized…”
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Synthesis, antiviral screening, and in silico investigations of new pyrimidine and pyridopyrimidine derivatives: Finding new therapeutic prospects to combat the herpes simplex virus (HSV-1)
Published in Journal of molecular structure (15-02-2025)“…•Fourteen novel derivatives derived from pyrimidine and pyridopyrimidine were synthesized.•These derivatives were in vitro evaluated against HSV-1.•The…”
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Novel indeno-pyrazole and indeno-pyrimidine conjugates: Synthesis, DFT, anticancer screening and in silico studies as potent tubulin inhibitors
Published in Journal of molecular structure (05-02-2025)“…•A series of novel indeno-pyrazole and indeno-pyrimidine conjugates were synthesized.•Ten of these derivatives were evaluated for their anticancer…”
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New poly heterocyclic compounds based on pyrimidine-2-thiones: synthesis, evaluation of putative antiviral agents, DFT calculation, and molecular modeling
Published in Journal of molecular structure (05-11-2023)“…Owing to the enormous increase in viral infections in recent years, novel antiviral candidates are both eagerly awaited and unquestionably essential for the…”
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