Search Results - "Elmslie, Robyn"

Continuous low-dose oral chemotherapy for adjuvant therapy of splenic hemangiosarcoma in dogs by Lana, S, U'ren, L, Plaza, S, Elmslie, R, Gustafson, D, Morley, P, Dow, S

“…Background: Hemangiosarcoma (HSA) is a highly metastatic and often rapidly fatal tumor in dogs. At present, conventional adjuvant chemotherapy provides only a…”
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Evaluation of a Novel Tumor Vaccine in Dogs with Hemangiosarcoma by U'Ren, L.W, Biller, B.J, Elmslie, R.E, Thamm, D.H, Dow, S.W

“…Background: Hemangiosarcoma (HSA) is a highly metastatic and often rapidly fatal tumor of dogs. At present, adjuvant chemotherapy is the only proven effective…”
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Continuous Low-Dose Oral Chemotherapy for Adjuvant Therapy of Splenic Hemangiosarcoma in Dogs by Lana, Susan, U'ren, Lance, Plaza, Susan, Elmslie, Robyn, Gustafson, Daniel, Morley, Paul, Dow, Steven

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Evaluation of liposomal clodronate for treatment of malignant histiocytosis in dogs by Hafeman, Scott, London, Cheryl, Elmslie, Robyn, Dow, Steven

“…Malignant histiocytosis (MH) is an aggressive cancer derived from myeloid lineage cells in both dogs and humans. In dogs, the tumor is characterized by the…”
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Rabacfosadine for naïve canine intermediate to large cell lymphoma: Efficacy and adverse event profile across three prospective clinical trials by Saba, Corey F., Clifford, Craig, Burgess, Kristine, Phillips, Brenda, Vail, David, Wright, Zachary, Curran, Katie, Fan, Timothy, Elmslie, Robyn, Post, Gerald, Thamm, Douglas

“…While current lymphoma therapies induce remission in most dogs, drug‐resistant relapse is common, creating a need for novel agents. Rabacfosadine (RAB), a…”
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Prospective evaluation of flow cytometric characteristics, histopathologic diagnosis and clinical outcome in dogs with naïve B‐cell lymphoma treated with a 19‐week CHOP protocol by Wolf‐Ringwall, Amber, Lopez, Lynelle, Elmslie, Robyn, Fowler, Brooke, Lori, Janet, Sfiligoi, Gabriella, Skope, Anne, Arnold, Erin, Hughes, Kelly L., Thamm, Douglas H., Ehrhart, E. J., Avery, Anne C., Lana, Susan E.

“…Canine B‐cell lymphoma is a clinically heterogenous disease; however, it is generally treated as a single disease entity. The purpose of this clinical trial…”
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Cancer stem cell populations in lymphoma in dogs and impact of cytotoxic chemotherapy by Hartley, Genevieve, Elmslie, Robyn, Murphy, Brent, Hopkins, Leone, Guth, Amanda, Dow, Steven

“…Cancer relapse following chemotherapy has been attributed in part to the presence of cancer stem cells (CSC), which drive tumour growth and metastasis and are…”
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Abstract A26: Monocyte depletion to amplify tumor vaccine immunity in a dog non-Hodgkin lymphoma model by Dow, Steven, Mitchell, Leah, Guth, Amanda, Regan, Dan, Burton, Jenna, Elmslie, Robyn

“…Abstract Background. Spontaneously-developing B cell lymphoma in dogs closely resembles non-Hodgkin lymphoma (NHL) in humans in many respects, including tumor…”
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Phase I study of liposome-DNA complexes encoding the interleukin-2 gene in dogs with osteosarcoma lung metastases by Dow, Steven, Elmslie, Robyn, Kurzman, Ilene, MacEwen, Gregory, Pericle, Federica, Liggitt, Denny

“…Systemic gene delivery using cationic liposome-DNA complexes (LDCs) has been shown to elicit potent antitumor activity in mice with tumor metastases to the…”
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Evaluation of a xenogeneic VEGF vaccine in dogs with soft tissue sarcoma by Kamstock, Debra, Elmslie, Robyn, Thamm, Douglas, Dow, Steven

“…Active immunization against pro-angiogenic growth factors or their receptors is an emerging strategy for controlling tumor growth and angiogenesis. Previous…”
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Doxorubicin and BAY 12-9566 for the Treatment of Osteosarcoma in Dogs: A Randomized, Double-Blind, Placebo-Controlled Study by Moore, Antony S., Dernell, William S., Ogilvie, Gregory K., Kristal, Orna, Elmslie, Robyn, Kitchell, Barbara, Susaneck, Steven, Rosenthal, Robert, Klein, Mary K., Obradovich, Joyce, Legendre, Alfred, Haddad, Tara, Hahn, Kevin, Powers, Barbara E., Warren, Darren

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Liposomal clodronate treatment for tumour macrophage depletion in dogs with soft-tissue sarcoma by Guth, A. M., Hafeman, S. D., Elmslie, R. E., Dow, S. W.

“…Increased numbers of tumour‐associated macrophages correlate with rapid tumour growth and metastasis in tumours. Thus, macrophage depletion has potential as a…”
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Interleukins: Biological Properties and Therapeutic Potential by Elmslie, Robyn E., Dow, Steven W., Ogilvie, Gregory K.

“…Interleukins are biologically active glycoproteins derived primarily from activated lymphocytes and macrophages. Tremendous insight into the biochemical and…”
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Efficacy of mitoxantrone against various neoplasms in dogs by Ogilvie, G K, Obradovich, J E, Elmslie, R E, Vail, D M, Moore, A S, Straw, R C, Dickinson, K, Cooper, M F, Withrow, S J

“…One hundred twenty-six dogs with histologically confirmed, measurable malignant tumors were evaluated in a prospective study to determine the response to the…”
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In vivo tumor transfection with superantigen plus cytokine genes induces tumor regression and prolongs survival in dogs with malignant melanoma by Dow, S W, Elmslie, R E, Willson, A P, Roche, L, Gorman, C, Potter, T A

“…In vivo transfection of established tumors with immunostimulatory genes can elicit antitumor immunity. Therefore, we evaluated the safety and efficacy of…”
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Doxorubicin and BAY 12-9566 for the treatment of osteosarcoma in dogs: a randomized, double-blind, placebo-controlled study by Moore, A.S, Dernell, W.S, Ogilvie, G.K, Kristal, O, Elmslie, R, Kitchell, B, Susaneck, S, Rosenthal, R, Klein, M.K, Obradovich, J

“…Background: This study was designed to assess the efficacy of a matrix metalloproteinase inhibitor in prolonging posttreatment survival for dogs with…”
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Toxicoses and efficacy associated with administration of mitoxantrone to cats with malignant tumors by Ogilvie, G K, Moore, A S, Obradovich, J E, Elmslie, R E, Vail, D M, Straw, R C, Salmon, M D, Klein, M K, Atwater, S W, Ciekot, P E

“…Eighty-seven cats with histologically confirmed malignant tumors were used in a prospective study to determine the toxicity of mitoxantrone, a dihydroxyquinone…”
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Toxicoses associated with administration of mitoxantrone to dogs with malignant tumors by Ogilvie, G K, Obradovich, J E, Elmslie, R E, Vail, D M, Moore, A S, Curtis, C R, Straw, R C, Dickinson, K, Cooper, M F, Withrow, S J

“…One hundred twenty-nine dogs with histologically confirmed malignant tumors were used in a prospective study to determine the toxicity of the new…”
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Use of a biological extract of Serratia marcescens to decrease doxorubicin-induced myelosuppression in dogs by Ogilvie, G K, Elmslie, R E, Cecchini, M, Walters, L M, Pearson, F C

“…Fifteen dogs were given doxorubicin, IV, at a dosage of 30 mg/m2 of body surface. A commercially available biological extract of Serratia marcescens (BESM) was…”
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Genetic immunotherapy for cancer by Elmslie, R E, Dow, S W

“…The application of gene therapy to the treatment of human and veterinary diseases offers an innovative addition to the clinician's treatment options. Gene…”
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