Search Results - "Elmslie, K"

Roscovitine, a cyclin‐dependent kinase inhibitor, affects several gating mechanisms to inhibit cardiac L‐type (Ca(V)1.2) calcium channels by Yarotskyy, V, Elmslie, K S

“…Background and purpose: L‐type calcium channels (Ca (V)1.2) play an important role in cardiac contraction. Roscovitine, a cyclin‐dependent kinase inhibitor and…”
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Slowed N-Type Calcium Channel (CaV2.2) Deactivation by the Cyclin-Dependent Kinase Inhibitor Roscovitine by Buraei, Zafir, Anghelescu, Mircea, Elmslie, Keith S.

“…The lack of a calcium channel agonist (e.g., BayK8644) for CaV2 channels has impeded their investigation. Roscovitine, a potent inhibitor of cyclin-dependent…”
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Calcium current modulation in frog sympathetic neurones: multiple neurotransmitters and G proteins by Elmslie, K S

“…1. Whole-cell calcium currents of bullfrog sympathetic neurones were partially inhibited by noradrenaline (NA), chicken-II-luteinizing hormone-releasing…”
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Neurotransmitters acting via different G proteins inhibit N-type calcium current by an identical mechanism in rat sympathetic neurons by Ehrlich, I, Elmslie, K S

“…1. We studied the mechanism of voltage-dependent inhibition of N-type calcium current by norepinephrine (NE) and vasoactive intestinal peptide (VIP) in adult…”
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Transmitter modulation of neuronal calcium channels by Jones, S W, Elmslie, K S

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Concentration dependence of neurotransmitter effects on calcium current kinetics in frog sympathetic neurones by Elmslie, K S, Jones, S W

“…1. Noradrenaline (NA) slows the activation kinetics of N-type calcium channels, via G proteins. It has been suggested that the G proteins act by binding…”
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Calcium channel blockers in the treatment of disease by Elmslie, Keith S.

“…Over the last 20 years the combination of patch clamp and molecular biology techniques have resulted in an explosion in our knowledge of the different calcium…”
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LHRH and GTP-gamma-S modify calcium current activation in bullfrog sympathetic neurons by Elmslie, K S, Zhou, W, Jones, S W

“…LHRH (chicken II luteinizing hormone-releasing hormone) partially reduces calcium currents and slows the activation kinetics of part of the remaining current…”
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Effects of temperature on calcium current of bullfrog sympathetic neurons by van Lunteren, E, Elmslie, K S, Jones, S W

“…1. The temperature dependence of whole-cell calcium current was studied in bullfrog sympathetic neurons. 2. The factor by which the peak calcium current…”
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Calcium current modulation in frog sympathetic neurones: L-current is relatively insensitive to neurotransmitters by Elmslie, K S, Kammermeier, P J, Jones, S W

“…1. Neurotransmitters (noradrenaline, NA; chicken II luteinizing hormone-releasing hormone, LHRH) and activators of G proteins (GTP-gamma-S and AlF3) partially…”
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Reluctant Gating of Single N-Type Calcium Channels during Neurotransmitter-Induced Inhibition in Bullfrog Sympathetic Neurons by Lee, Hye Kyung, Elmslie, Keith S

“…Whole-cell recordings have been used to extensively characterize the voltage-dependent inhibition of N-type calcium current induced by various…”
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Identification of the Single Channels that Underlie the N-Type and L-Type Calcium Currents in Bullfrog Sympathetic Neurons by Elmslie, Keith S

“…Most of the whole-cell calcium current of frog sympathetic neurons is an N-type current, blocked by omega-conotoxin GVIA (omegaCGVIA). Thus, these cells should…”
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Phosphorylation enhances inactivation of N-type calcium channel current in bullfrog sympathetic neurons by WERZ, M. A, ELMSLIE, K. S, JONES, S. W

“…We have investigated the effects of phosphatase and protein kinase inhibitors on calcium channel currents of bullfrog sympathetic neurons using the whole cell…”
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Gating of single N-type calcium channels recorded from bullfrog sympathetic neurons by Lee, H K, Elmslie, K S

“…For many neurons, N-type calcium channels provide the primary pathway for calcium influx during an action potential. We investigated the gating properties of…”
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Progression to AIDS and predictors of AIDS in seroprevalent and seroincident cohorts of homosexual men by Schechter, M T, Craib, K J, Le, T N, Willoughby, B, Douglas, B, Sestak, P, Montaner, J S, Weaver, M S, Elmslie, K D, O'Shaughnessy, M V

“…As part of an ongoing prospective study of seropositive homosexual men in Vancouver, Canada, a seroprevalent cohort of 246 subjects (i.e. duration of infection…”
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Effects of kynurenate on root potentials evoked by synaptic activity and amino acids in the frog spinal cord by Elmslie, K S, Yoshikami, D

“…The effects of kynurenate (Kyn) on synaptic- and excitatory amino acid-mediated responses in isolated, hemisected spinal cords of frog were examined. Kyn (0.5…”
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National surveillance program on occupational exposure to the human immunodeficiency virus among health care workers in Canada

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AIDS and women by Elmslie, K D

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Intracellular ATP and GTP are both required to preserve modulation of N-type calcium channel current by norepinephrine by ELMSLIE, K. S, WERZ, M. A, OVERHOLT, J. L, JONES, S. W

“…Norepinephrine (NE) inhibits voltage-dependent calcium channels of sympathetic neurons. We investigated the role of intracellular nucleotides in this…”
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Reevaluation of Ca2+ channel types and their modulation in bullfrog sympathetic neurons by Elmslie, K S, Kammermeier, P J, Jones, S W

“…With 90 mM Ba2+, the main Ca2+ current in frog sympathetic neurons peaks near +30 mV and is blocked by omega-conotoxin GVIA (omega-CgTx). It is modulated by…”
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