Search Results - "Elmoselhi, Adel B."

Advantages of Understanding the Molecular Mechanisms of Angiogenesis in Various Physiological and Pathological Conditions by Elmoselhi, Adel B

“…The aim of this Special Issue is to highlight the diverse benefits and approaches to studying angiogenesis in various physiological and pathological…”
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Muscle unloading: A comparison between spaceflight and ground‐based models by Qaisar, Rizwan, Karim, Asima, Elmoselhi, Adel B.

“…Prolonged unloading of skeletal muscle, a common outcome of events such as spaceflight, bed rest and hindlimb unloading, can result in extensive metabolic,…”
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Circulating microRNAs as potential biomarkers of early vascular damage in vitamin D deficiency, obese, and diabetic patients by Elmoselhi, Adel B, Seif Allah, Mohamed, Bouzid, Amal, Ibrahim, Zeinab, Venkatachalam, Thenmozhi, Siddiqui, Ruqaiyyah, Khan, Naveed Ahmed, Hamoudi, Rifat A

“…Vitamin D3 deficiency, obesity, and diabetes mellitus (DM) have been shown to increase the risk of cardiovascular diseases (CVDs). However, the early detection…”
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Retinal vascular changes and arterial stiffness during 8-month isolation and confinement: the SIRIUS-21 space analog mission by Elmoselhi, Adel B, Shankhwar, Vishwajeet, Qaisar, Rizwan, Hamoudi, Rifat, Brix, Bianca, Salon, Adam, Goswami, Nandu

“…Isolation and confinement are significant stressors during space travel that can impact crewmembers' physical and mental health. Space travel has been shown to…”
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PRMT5 Selective Inhibitor Enhances Therapeutic Efficacy of Cisplatin in Lung Cancer Cells by Bajbouj, Khuloud, Ramakrishnan, Rakhee K., Saber-Ayad, Maha, Omar, Hany A., Saheb Sharif-Askari, Narjes, Shafarin, Jasmin, Elmoselhi, Adel B., Ihmaid, Ahmed, AlHaj Ali, Suhib, Alalool, Abdulla, Abdullah, Reem, Hamid, Qutayba

“…As a therapeutic approach, epigenetic modifiers have the potential to enhance the efficacy of chemotherapeutic agents. Protein arginine methyltransferase 5…”
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Gut matters in microgravity: potential link of gut microbiota and its metabolites to cardiovascular and musculoskeletal well-being by Ibrahim, Zeinab, Khan, Naveed A, Siddiqui, Ruqaiyyah, Qaisar, Rizwan, Marzook, Hezlin, Soares, Nelson C, Elmoselhi, Adel B

“…The gut microbiota and its secreted metabolites play a significant role in cardiovascular and musculoskeletal health and diseases. The dysregulation of the…”
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Space medicine: gut microbiome of hardy species is a potential source to counter disorders during space travel by Siddiqui, Ruqaiyyah, Elmoselhi, Adel B, Khan, Naveed Ahmed

“…It is proposed that gut microbiome of species like cockroaches may offer a potential source of novel mechanisms/molecules that can be translated into humans to…”
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Synergistic Anti-Angiogenic Effect of Combined VEGFR Kinase Inhibitors, Lenvatinib, and Regorafenib: A Therapeutic Potential for Breast Cancer by Bajbouj, Khuloud, Qaisar, Rizwan, Alshura, Mohammed A, Ibrahim, Zeinab, Alebaji, Mohamad B, Al Ani, Amenah W, Janajrah, Hanadi M, Bilalaga, Mariah M, Omara, Abdelrahman I, Abou Assaleh, Rebal S, Saber-Ayad, Maha M, Elmoselhi, Adel B

“…Background: Breast cancer currently affects more than two million women worldwide, and its incidence is steadily increasing. One of the most essential factors…”
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Vitamin D Exerts Significant Antitumor Effects by Suppressing Vasculogenic Mimicry in Breast Cancer Cells by Bajbouj, Khuloud, Al-Ali, Abeer, Shafarin, Jasmin, Sahnoon, Lina, Sawan, Ahmad, Shehada, Ahmed, Elkhalifa, Walaaeldin, Saber-Ayad, Maha, Muhammad, Jibran Sualeh, Elmoselhi, Adel B., Guraya, Salman Y., Hamad, Mawieh

“…Background Numerous clinical and experimental observations have alluded to the substantial anti-neoplastic role of vitamin D in breast cancer (BC), primarily…”
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Serum multi-omics analysis in hindlimb unloading mice model: Insights into systemic molecular changes and potential diagnostic and therapeutic biomarkers by Ibrahim, Zeinab, Khan, Naveed A., Qaisar, Rizwan, Saleh, Mohamed A., Siddiqui, Ruqaiyyah, Al-Hroub, Hamza M., Giddey, Alexander D., Semreen, Mohammad Harb, Soares, Nelson C., Elmoselhi, Adel B.

“…Microgravity, in space travel and prolonged bed rest conditions, induces cardiovascular deconditioning along with skeletal muscle mass loss and weakness. The…”
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Unveiling the molecular Culprit of arterial stiffness in vitamin D deficiency and obesity: Potential for novel therapeutic targets by Elmoselhi, Adel B., Bouzid, Amal, Allah, Mohamed Seif, Ibrahim, Zeinab, Bajbouj, Khuloud, Abou Assaleh, Rebal S., Venkatachalam, Thenmozhi, Madkour, Mohamed, Siddiqui, Ruqaiyyah, Khan, Naveed Ahmed, Hamoudi, Rifat A.

“…Cardiovascular diseases (CVDs) are highly associated with both vitamin D deficiency and obesity, two prevalent health conditions worldwide. Arterial stiffness,…”
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Antiamoebic Properties of Laboratory and Clinically Used Drugs against Naegleria fowleri and Balamuthia mandrillaris by Siddiqui, Ruqaiyyah, Mungroo, Mohammad Ridwane, Anuar, Tengku Shahrul, Alharbi, Ahmad M, Alfahemi, Hasan, Elmoselhi, Adel B, Khan, Naveed Ahmed

“…Naegleria fowleri and Balamuthia mandrillaris are pathogenic free-living amoebae that infect the central nervous system with over 95% mortality rates. Although…”
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Nicotinamide riboside kinase-2 alleviates ischemia-induced heart failure through P38 signaling by Ahmad, Firdos, Tomar, Dhanendra, Aryal A C, Smriti, Elmoselhi, Adel B., Thomas, Manfred, Elrod, John W., Tilley, Douglas G., Force, Thomas

“…Nicotinamide riboside kinase-2 (NRK-2), a muscle-specific β1 integrin binding protein, predominantly expresses in skeletal muscle with a trace amount expressed…”
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Cardiovascular changes under the microgravity environment and the gut microbiome by Siddiqui, Ruqaiyyah, Qaisar, Rizwan, Al-Dahash, Khulood, Altelly, Ahmad Hashem, Elmoselhi, Adel B, Khan, Naveed Ahmed

“…In view of the critical role the gut microbiome plays in human health, it has become clear that astronauts' gut microbiota composition changes after spending…”
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RhoA/ROCK inhibition attenuates endothelin-1–induced glomerulopathy in the rats by Saleh, Mohamed A., Shaaban, Ahmed A., Talaat, Iman M., Elmougy, Atef, Adra, Saryia F., Ahmad, Firdos, Qaisar, Rizwan, Elmoselhi, Adel B., Abu-Gharbieh, Eman, El-Huneidi, Waseem, Eladl, Mohamed A., Shehatou, George, Kafl, Hoda E.

“…Endothelin-1 (ET-1) contributes to the development of kidney diseases. However, the underlying molecular mechanism is largely undefined. Here we sought to…”
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Hind-limb unloading in rodents: Current evidence and perspectives by Hawliczek, Anna, Brix, Bianca, Al Mutawa, Shamma, Alsuwaidi, Hanan, Du Plessis, Stefan, Gao, Yunfang, Qaisar, Rizwan, Siddiqui, Ruqaiyyah, Elmoselhi, Adel B., Goswami, Nandu

“…Due to scarcity of available biological samples from returning space explorers, alternative models, which improve the understanding of spaceflight-related…”
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Suppression of endoplasmic reticulum stress restores renal microarchitecture in a mouse model of simulated microgravity by Ramachandran, Gopika, Elmoselhi, Adel B, Qaisar, Rizwan, Kamath, Deepika

“…ABSTRACT Background: Hindlimb-unloaded (HU) mice are animal models of simulated microgravity that exhibit pathological changes in several organs; however,…”
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Echocardiography as an important tool for teaching and learning in the preclinical phase of the medical school curriculum by Shehata, Mohamed Seif Allah, Eladl, Mohamed Ahmad, Alhuarrat, Majd Al-Deen, Elmoselhi, Adel B.

“…Background: A transformation in medical education is currently underway, prioritizing competency and clinical integration with basic sciences. This study…”
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Diversity in microbiota between Indian and Emiratis ethnicities is associated with benign prostatic hyperplasia by Al Shareef, Zainab, Khan, Naveed Ahmed, Ershaid, Mai Nidal Asad, Soliman, Sameh, Elmoselhi, Adel B.

“…Background: Herein, we investigated the correlation between microbiota profile and benign prostatic hyperplasia (BPH) in patients from two different…”
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Preconditioning attenuates ischemia-reperfusion-induced remodeling of Na+-K+-ATPase in hearts by Elmoselhi, Adel B, Lukas, Anton, Ostadal, Petr, Dhalla, Naranjan S

“…The aim of this study was to determine whether changes in protein content and/or gene expression of Na+-K+-ATPase subunits underlie its decreased enzyme…”
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