Search Results - "Elmer, Gregory I"

Prenatal exposure to a repeated variable stress paradigm elicits behavioral and neuroendocrinological changes in the adult offspring: potential relevance to schizophrenia by Koenig, James I., Elmer, Gregory I., Shepard, Paul D., Lee, Paul R., Mayo, Cheryl, Joy, Brian, Hercher, Ericka, Brady, Dana L.

“…Exposure to stress during gestation induces marked changes in the behavior of the affected offspring. Examining the consequences of prenatal stress may prove…”
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New replicable anxiety-related measures of wall vs. center behavior of mice in the open field by Lipkind, Dina, Sakov, Anat, Kafkafi, Neri, Elmer, Gregory I, Benjamini, Yoav, Golani, Ilan

“…1 Department of Zoology, George S. Wise Faculty of Life Sciences, and 2 Department of Statistics and Operations Research, The Sackler Faculty of Exact…”
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SEE Locomotor Behavior Test Discriminates C57BL/6J and DBA/2J Mouse Inbred Strains Across Laboratories and Protocol Conditions by Kafkafi, Neri, Lipkind, Dina, Benjamini, Yoav, Mayo, Cheryl L, Elmer, Gregory I, Golani, Ilan

“…Conventional tests of behavioral phenotyping frequently have difficulties differentiating certain genotypes and replicating these differences across…”
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Activity density in the open field: a measure for differentiating the effect of psychostimulants by Kafkafi, Neri, Elmer, Gregory I.

“…Traditional open-field activity measures do not provide a sharp behavioral differentiation across psychomotor stimulants such as d-amphetamine (AMPH) and…”
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Genetic variance in nociception and its relationship to the potency of morphine-induced analgesia in thermal and chemical tests by Elmer, Gregory I, Pieper, Jeanne O, Negus, Stevens S, Woods, James H

“…The perceived intensity of a painful stimulus is determined in part by the stimulus intensity and environmental conditions. The purpose of this study was to…”
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Cocaine-induced locomotor activity and cocaine discrimination in dopamine D2 receptor mutant mice by CHAUSMER, Allison L, ELMER, Gregory I, RUBINSTEIN, Marcelo, LOW, Malcolm J, GRANDY, David K, KATZ, Jonathan L

“…Dopamine (DA) D2-like antagonists block several effects of cocaine, including its locomotor stimulant and interoceptive discriminative-stimulus effects…”
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Social memory in mice: Disruption with an NMDA antagonist and attenuation with antipsychotic drugs by Gao, Xue-Min, Elmer, Gregory I., Adams-Huet, Beverley, Tamminga, Carol A.

“…Social recognition reflects the ability of one animal to learn and remember the identity of another. Animal models of social learning and memory are pertinent…”
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Data Mining in a Behavioral Test Detects Early Symptoms in a Model of Amyotrophic Lateral Sclerosis by Kafkafi, Neri, Yekutieli, Daniel, Yarowsky, Paul, Elmer, Gregory I

“…"What's wrong with my genetically engineered animal?" is a common yet often difficult to answer question in behavioral phenotyping. We present here a method…”
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Associating quantitative behavioral traits with gene expression in the brain: searching for diamonds in the hay by Reiner-Benaim, Anat, Yekutieli, Daniel, Letwin, Noah E., Elmer, Gregory I., Lee, Norman H., Kafkafi, Neri, Benjamini, Yoav

“…Gene expression and phenotypic functionality can best be associated when they are measured quantitatively within the same experiment. The analysis of such a…”
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Darting behavior: a quantitative movement pattern designed for discrimination and replicability in mouse locomotor behavior by Kafkafi, Neri, Pagis, Michal, Lipkind, Dina, Mayo, Cheryl L., Bemjamini, Yoav, Golani, Ilan, Elmer, Gregory I.

“…In the open-field behavior of rodents, Software for Exploring Exploration (SEE) can be used for an explicit design of behavioral endpoints with high genotype…”
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Cocaine-induced locomotor activity and cocaine discrimination in dopamine D4 receptor mutant mice by KATZ, Jonathan L, CHAUSMER, Allison L, ELMER, Gregory I, RUBINSTEIN, Marcelo, LOW, Malcolm J, GRANDY, David K

“…Previous studies have found a role for dopamine D(2)-like receptors in many of the behavioral effects of cocaine, including its stimulation of locomotor…”
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Approaches to multiplicity issues in complex research in microarray analysis by Yekutieli, Daniel, Reiner-Benaim, Anat, Benjamini, Yoav, Elmer, Gregory I., Kafkafi, Neri, Letwin, Noah E., Lee, Norman H.

“…The multiplicity problem is evident in the simplest form of statistical analysis of gene expression data – the identification of differentially expressed…”
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Phentermine and Fenfluramine: Preclinical Studies in Animal Models of Cocaine Addiction by ROTHMAN, RICHARD B., ELMER, GREGORY I., SHIPPENBERG, TONI S., REA, WILLIAM, BAUMANN, MICHAEL H.

“…Combined dopamine (DA) and 5‐hydroxytryptamine (5‐HT) releasers such as phentermine (PHEN) and fenfluramine (FEN) are reported, in open label studies, to…”
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Opioid receptor selectivity of heroin given intracerebroventricularly differs in six strains of inbred mice by Rady, J J, Elmer, G I, Fujimoto, J M

“…Heroin administered i.c.v. acts on supraspinal mu opioid receptors in ICR mice but on delta receptors in Swiss Webster mice. The purpose of this study was to…”
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Operant rate depressant effects of ethanol in mice selectively bred for differential neurosensitivity to ethanol by Elmer, G I, George, F R

“…Few studies have investigated genetic differences in the effects of ethanol on operant schedule-controlled behaviors. The use of genetically defined…”
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Cocaine-induced locomotor activity and cocaine discrimination in dopamine D 4 receptor mutant mice by Katz, Jonathan L., Chausmer, Allison L., Elmer, Gregory I., Rubinstein, Marcelo, Low, Malcolm J., Grandy, David K.

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The neurobiology of opiate reinforcement by Shippenberg, T S, Elmer, G I

“…This article provides a basic introduction into two commonly used behavioral paradigms used for the assessment of the reinforcing and rewarding effects of…”
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Differential neuroendocrine responsiveness to morphine in Lewis, Fischer 344, and ACI inbred rats by Baumann, Michael H., Elmer, Gregory I., Goldberg, Steve R., Ambrosio, Emilio

“…Preclinical evidence suggests there is a link between the responsiveness to stress and the propensity to self-administer drugs of abuse. Our previous findings,…”
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Opioid operant self-administration, analgesia, stimulation and respiratory depression in μ-deficient mice by ELMER, G. I, PIEPER, J. O, GOLDBERG, S. R, GEORGE, F. R

“…It is commonly thought that mu-receptors play an important role in the reinforcing effects of opioids. In the present study, inbred strains widely divergent in…”
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The role of specific eicosanoids in mediating the acute narcotic effects of ethanol by Elmer, G I, George, F R

“…The pharmacological effects of ethanol may be in part due to increased membrane fluidity, resulting in increased phospholipase A2 activity and the subsequent…”
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