Search Results - "Elmehriki, Adam A H"
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A Remarkably Simple Protocol for the N-Formylation of Amino Acid Esters and Primary Amines
Published in Organic letters (05-08-2011)“…A simple, convenient, and wide scope protocol for the N-formylation of amino acid esters and primary amines has been developed utilizing only imidazole in warm…”
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A Spiroalkylation Method for the Stereoselective Construction of α‑Quaternary Carbons and Its Application to the Total Synthesis of (R)‑Puraquinonic Acid
Published in Organic letters (06-12-2019)“…Cyclic α-quaternary carbon stereocenters were prepared from biselectrophillic substrates and an easily prepared chiral bicyclic sulfonyl lactam. This was…”
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A DOTAM-based paraCEST agent favoring TSAP geometry for enhanced amide proton chemical shift dispersion and temperature sensitivity
Published in Contrast media and molecular imaging (01-05-2013)“…The Tm(3+) chelate of DOTAM [1,4,7,10-tetrakis(carbamoylmethyl)-1,4,7,10-tetraazacyclododecane] possessing sterically demanding t-butyl amide substitution…”
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Introduction of Peripheral Carboxylates to Decrease the Charge on Tm3+ DOTAM-Alkyl Complexes: Implications for Detection Sensitivity and in Vivo Toxicity of PARACEST MRI Contrast Agents
Published in Journal of medicinal chemistry (27-08-2015)“…A series of structurally modified Tm3+ DOTAM-alkyl complexes as potential PARACEST MRI contrast agents has been synthesized with the aim to decrease the…”
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Synthesis and spectral characterization of environmentally responsive fluorescent deoxycytidine analogs
Published in Artificial DNA, PNA & XNA (2014)“…Herein, we describe the synthesis and spectroscopic properties of five novel pyrrolodeoxycytidine analogs, and the related…”
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Complexes of selected late period lanthanide(III) cations with 1,4,7,10-tetraazacyclododecane-1,4,7,10-tetraacetic acid amide (DOTAM)-alkyl ligands — A new platform for the development of paramagnetic chemical exchange saturation transfer (PARACEST) magnetic resonance imaging (MRI) contrast agents
Published in Canadian journal of chemistry (01-03-2013)“…A series of 18 1,4,7,10-tetraazacyclododecane-1,4,7,10-tetraacetic acid amide (DOTAM)-alkyl derived complexes with selected late lanthanide(III) cations (Dy 3+…”
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Introduction of Peripheral Carboxylates to Decrease the Charge on Tm(3+) DOTAM-Alkyl Complexes: Implications for Detection Sensitivity and in Vivo Toxicity of PARACEST MRI Contrast Agents
Published in Journal of medicinal chemistry (27-08-2015)“…A series of structurally modified Tm(3+) DOTAM-alkyl complexes as potential PARACEST MRI contrast agents has been synthesized with the aim to decrease the…”
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