Search Results - "Elmaarouf, Abderrahman"
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Mutant three-repeat tau expression initiates retinal ganglion cell death through Caspase-2
Published in Neurobiology of disease (01-05-2021)“…The microtubule-associated protein tau is implicated in multiple degenerative diseases including retinal diseases such as glaucoma; however, the way tau…”
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Binding Characteristics of PRX012 Surrogate Demonstrate Potent Engagement of Toxic Amyloid Beta Protofibrils and Robust Clearance of Pyroglutamate-modified Amyloid Beta (P7-9.003)
Published in Neurology (09-04-2024)“…Abstract only…”
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Development of a dual Aβ‐tau vaccine for the prevention of Alzheimer’s disease
Published in Alzheimer's & dementia (01-12-2021)“…Background Alzheimer’s disease (AD) is characterized by two pathological hallmarks, Aβ plaques and tau tangles. Several antibodies targeting Aβ plaques showed…”
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PRX012 induces microglia‐mediated clearance of pyroglutamate‐modified Aβ in Alzheimer’s Disease brain tissue
Published in Alzheimer's & dementia (01-12-2021)“…Background Alzheimer’s disease (AD) is a devastating neurodegenerative disorder featuring hallmark Aβ plaques that spread throughout the brain as the disease…”
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