Search Results - "Ellory, J. C"

Oxygen-sensitive membrane transporters in vertebrate red cells by Gibson, J S, Cossins, A R, Ellory, J C

“…Oxygen is essential for all higher forms of animal life. It is required for oxidative phosphorylation, which forms the bulk of the energy supply of most…”
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Chronic exercise reduces platelet activation in hypertension: upregulation of the l-arginine-nitric oxide pathway by De Meirelles, L. R., Mendes-Ribeiro, A. C., Mendes, M. A. P., Da Silva, M. N. S. B., John Clive Ellory, J. C., Mann, G. E., Brunini, T. M. C.

“…Nitric oxide (NO) inhibits platelet function and plays a key role in the regulation of cardiovascular homeostasis. Essential hypertension is characterized by…”
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Abnormalities in l-arginine transport and nitric oxide biosynthesis in chronic renal and heart failure by Mendes Ribeiro, A.C., Brunini, T.M.C., Ellory, J.C., Mann, G.E.

“…Abstract Patients with chronic renal and heart failure present with hypertension and widespread vasoconstriction, respectively. Although systemic release of…”
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Differential expression of volume-regulated anion channels during cell cycle progression of human cervical cancer cells by Shen, Meng‐Ru, Droogmans, Guy, Eggermont, Jan, Voets, Thomas, Ellory, J. Clive, Nilius, Bernd

“…This study investigated the volume-regulated anion channel (VRAC) of human cervical cancer SiHa cells under various culture conditions, testing the hypothesis…”
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Rubidium fluxes in Xenopus laevis (Amphibia) erythrocytes induced by swelling and relationship with taurine pathway by Katz, U, Lancaster, J. -A, Ellory, J. C

“…Rubidium (⁸⁶Rb⁺) fluxes were used to probe for K⁺ uptake in Xenopus erythrocytes in vitro following exposure to various ambient osmolalities. Rb⁺ uptake is…”
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The Properties of Red Blood Cells from Patients Heterozygous for HbS and HbC (HbSC Genotype) by Rees, David Charles, Hannemann, A., Gibson, John Stanley, Ellory, J. C., Dalibalta, S., Weiss, Erwin

“…Sickle cell disease (SCD) is one of the commonest severe inherited disorders, but specific treatments are lacking and the pathophysiology remains unclear…”
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Transport of diverse substrates into malaria-infected erythrocytes via a pathway showing functional characteristics of a chloride channel by KIRK, K, HORNER, H. A, ELFORD, B. C, ELLORY, J. C, NEWBOLD, C. I

“…Following infection by the malaria parasite, Plasmodium falciparum, human erythrocytes show increased permeability to a variety of low molecular weight…”
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The conductance of red blood cells from sickle cell patients: ion selectivity and inhibitors by Ma, Y.‐L., Rees, D. C., Gibson, J. S., Ellory, J. C.

“…Key points  •  The high cation permeability in red blood cells (RBCs) from patients with sickle cell disease (SCD) is central to pathogenesis and includes a…”
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ACTIVATION OF l-ARGININE TRANSPORT IN UNDIALYSED CHRONIC RENAL FAILURE AND CONTINUOUS AMBULATORY PERITONEAL DIALYSIS PATIENTS by Brunini, TMC, Roberts, NB, Yaqoob, MM, Ellory, JC, Mann, GE, Ribeiro, AC Mendes

“…SUMMARY 1 Treatment with haemodialysis and continuous ambulatory peritoneal dialysis (CAPD) presents different pathophysiological profiles and it has been…”
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Differential oxygen sensitivity of the K+‐Cl− cotransporter in normal and sickle human red blood cells by Gibson, J. S., Speake, P. F., Ellory, J. C.

“…1 K+ influx and efflux were measured in normal (HbA) and sickle (HbS) red blood cells to investigate the interaction of swelling, H+ ions and urea with O2 (0…”
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Membrane Transport in Sickle Cell Disease by Gibson, J.S., Ellory, J.C.

“…ABSTRACT We have reviewed here a number of membrane transport events in red cells from normal individuals and sickle cell patients which respond to changes in…”
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A non‐electrolyte haemolysis assay for diagnosis and prognosis of sickle cell disease by Milligan, C., Rees, D. C., Ellory, J. C., Osei, A., Browning, J. A., Hannemann, A., Gibson, J. S.

“…Key points Red blood cells (RBCs) from the two main genotypes of sickle cell disease (SCD) patients showed haemolysis in deoxygenated isosmotic sucrose…”
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Surviving in a matrix: membrane transport in articular chondrocytes by Wilkins, R J, Browning, J A, Ellory, J C

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O2 dependence of K+ transport in sickle cells: the effect of different cell populations and the substituted benzaldehyde 12C79 by GIBSON, J. S., KHAN, A, SPEAKE, P. F., ELLORY, J. C.

“…ABSTRACT The molecular basis of sickle cell disease (SCD) is well known but the pathophysiology is poorly understood. It remains intractable to therapy…”
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Transport of organic substrates via a volume-activated channel by KIRK, K, CLIVE ELLORY, J, YOUNG, J. D

“…We have investigated the volume-activated transport of organic solutes in flounder erythrocytes. Osmotic swelling of cells suspended in a Na(+)-free medium led…”
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Neutral amino acid transport in bovine articular chondrocytes by Barker, G. A., Wilkins, R. J., Golding, S., Ellory, J. C.

“…The sodium-dependent amino acid transport systems responsible for proline, glycine and glutamine transport, together with the sodium-independent systems for…”
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KCl cotransport activation in human erythrocytes by high hydrostatic pressure by Godart, H, Ellory, J C

“…1. Pressure induced a 4- to 5-fold stimulation of the residual (i.e. oubain-bumetanide insensitive) 86Rb+ influx across the human red cell membrane. This…”
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Swelling-activated amino acid efflux in the human neuroblastoma cell line CHP-100 by Basavappa, S, Huang, C C, Mangel, A W, Lebedev, D V, Knauf, P A, Ellory, J C

“…1. The effects of hypoosmotic stress on cell volume and amino acid efflux were evaluated in the human neuroblastoma cell line CHP-100 with the Coulter Counter…”
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Effects of low ionic strength media on passive human red cell monovalent cation transport by Bernhardt, I, Hall, A C, Ellory, J C

“…1. The effect of low ionic strength media on the residual, i.e. (ouabain + bumetanide + Ca2+)-insensitive, K+ influx was characterized in human red blood…”
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Variations of intracellular pH in human erythrocytes via K(+)(Na(+))/H(+) exchange under low ionic strength conditions by Kummerow, D, Hamann, J, Browning, J A, Wilkins, R, Ellory, J C, Bernhardt, I

“…The change of intracellular pH of erythrocytes under different experimental conditions was investigated using the pH-sensitive fluorescent dye BCECF and…”
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