Search Results - "Ellison, Stephanie J"

An essential role for Argonaute 2 in EGFR-KRAS signaling in pancreatic cancer development by Shankar, Sunita, Tien, Jean Ching-Yi, Siebenaler, Ronald F., Chugh, Seema, Dommeti, Vijaya L., Zelenka-Wang, Sylvia, Wang, Xiao-Ming, Apel, Ingrid J., Waninger, Jessica, Eyunni, Sanjana, Xu, Alice, Mody, Malay, Goodrum, Andrew, Zhang, Yuping, Tesmer, John J., Mannan, Rahul, Cao, Xuhong, Vats, Pankaj, Pitchiaya, Sethuramasundaram, Ellison, Stephanie J., Shi, Jiaqi, Kumar-Sinha, Chandan, Crawford, Howard C., Chinnaiyan, Arul M.

“…Both KRAS and EGFR are essential mediators of pancreatic cancer development and interact with Argonaute 2 (AGO2) to perturb its function. Here, in a mouse…”
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Antisense oligonucleotides to therapeutically target SARS-CoV-2 infection by Qiao, Yuanyuan, Wotring, Jesse W, Zhang, Charles J, Jiang, Xia, Xiao, Lanbo, Watt, Andy, Gattis, Danielle, Scandalis, Eli, Freier, Susan, Zheng, Yang, Pretto, Carla D, Ellison, Stephanie J, Swayze, Eric E, Guo, Shuling, Sexton, Jonathan Z, Chinnaiyan, Arul M

“…Although the COVID-19 pandemic began over three years ago, the virus responsible for the disease, SARS-CoV-2, continues to infect people across the globe. As…”
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Biological implications of polydimethylsiloxane-based microfluidic cell culture by Regehr, Keil J, Domenech, Maribella, Koepsel, Justin T, Carver, Kristopher C, Ellison-Zelski, Stephanie J, Murphy, William L, Schuler, Linda A, Alarid, Elaine T, Beebe, David J

“…Polydimethylsiloxane (PDMS) has become a staple of the microfluidics community by virtue of its simple fabrication process and material attributes, such as gas…”
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Decreased expression of the satiety signal receptor CCKAR is responsible for increased growth and body weight during the domestication of chickens by Dunn, Ian C, Meddle, Simone L, Wilson, Peter W, Wardle, Chloe A, Law, Andy S, Bishop, Valerie R, Hindar, Camilla, Robertson, Graeme W, Burt, Dave W, Ellison, Stephanie J H, Morrice, David M, Hocking, Paul M

“…Animal domestication has resulted in changes in growth and size. It has been suggested that this may have involved selection for differences in appetite…”
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Single-cell analyses of renal cell cancers reveal insights into tumor microenvironment, cell of origin, and therapy response by Zhang, Yuping, Narayanan, Sathiya P., Mannan, Rahul, Raskind, Gregory, Wang, Xiaoming, Vats, Pankaj, Su, Fengyun, Hosseini, Noshad, Cao, Xuhong, Kumar-Sinha, Chandan, Ellison, Stephanie J., Giordano, Thomas J., Morgan, Todd M., Pitchiaya, Sethuramasundaram, Alva, Ajjai, Mehra, Rohit, Cieslik, Marcin, Dhanasekaran, Saravana M., Chinnaiyan, Arul M.

“…Diverse subtypes of renal cell carcinomas (RCCs) display a wide spectrum of histomorphologies, proteogenomic alterations, immune cell infiltration patterns,…”
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Targeting transcriptional regulation of SARS-CoV-2 entry factors ACE2 and TMPRSS2 by Qiao, Yuanyuan, Wang, Xiao-Ming, Mannan, Rahul, Pitchiaya, Sethuramasundaram, Zhang, Yuping, Wotring, Jesse W., Xiao, Lanbo, Robinson, Dan R., Wu, Yi-Mi, Tien, Jean Ching-Yi, Cao, Xuhong, Simko, Stephanie A., Apel, Ingrid J., Bawa, Pushpinder, Kregel, Steven, Narayanan, Sathiya P., Raskind, Gregory, Ellison, Stephanie J., Parolia, Abhijit, Zelenka-Wang, Sylvia, McMurry, Lisa, Su, Fengyun, Wang, Rui, Cheng, Yunhui, Delekta, Andrew D., Mei, Zejie, Pretto, Carla D., Wang, Shaomeng, Mehra, Rohit, Sexton, Jonathan Z., Chinnaiyan, Arul M.

“…Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the virus responsible for COVID-19, employs two key host proteins to gain entry and replicate…”
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Temporal variation in estrogen receptor-α protein turnover in the presence of estrogen by Valley, Christopher C, Solodin, Natalia M, Powers, Ginny L, Ellison, Stephanie J, Alarid, Elaine T

“…Estrogen receptor-α (ERα) is essential in the maintenance of cellular responsiveness to estrogen in the reproductive system. It is established that ligand…”
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Repression of ESR1 through Actions of Estrogen Receptor Alpha and Sin3A at the Proximal Promoter by Ellison-Zelski, Stephanie J., Solodin, Natalia M., Alarid, Elaine T.

“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Regulation of Estrogen Receptor α N-Terminus Conformation and Function by Peptidyl Prolyl Isomerase Pin1 by Rajbhandari, Prashant, Finn, Greg, Solodin, Natalia M, Singarapu, Kiran K, Sahu, Sarata C, Markley, John L, Kadunc, Kelley J, Ellison-Zelski, Stephanie J, Kariagina, Anastasia, Haslam, Sandra Z, Lu, Kun Ping, Alarid, Elaine T

“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Proxalutamide reduces SARS-CoV-2 infection and associated inflammatory response by Qiao, Yuanyuan, Wotring, Jesse W, Zheng, Yang, Zhang, Charles J, Zhang, Yuping, Jiang, Xia, Pretto, Carla D, Eyunni, Sanjana, Parolia, Abhijit, He, Tongchen, Cheng, Caleb, Cao, Xuhong, Wang, Rui, Su, Fengyun, Ellison, Stephanie J, Wang, Yini, Qin, Jun, Yan, Honghua, Zhou, Qianxiang, Ma, Liandong, Sexton, Jonathan Z, Chinnaiyan, Arul M

“…Early in the COVID-19 pandemic, data suggested that males had a higher risk of developing severe disease and that androgen deprivation therapy might be…”
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Androgen receptor antagonism drives cytochrome P450 17A1 inhibitor efficacy in prostate cancer by Norris, John D, Ellison, Stephanie J, Baker, Jennifer G, Stagg, David B, Wardell, Suzanne E, Park, Sunghee, Alley, Holly M, Baldi, Robert M, Yllanes, Alexander, Andreano, Kaitlyn J, Stice, James P, Lawrence, Scott A, Eisner, Joel R, Price, Douglas K, Moore, William R, Figg, William D, McDonnell, Donald P

“…The clinical utility of inhibiting cytochrome P450 17A1 (CYP17), a cytochrome p450 enzyme that is required for the production of androgens, has been…”
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Autophagy Inhibition by Targeting PIKfyve Potentiates Response to Immune Checkpoint Blockade in Prostate Cancer by Qiao, Yuanyuan, Choi, Jae Eun, Tien, Jean C, Simko, Stephanie A, Rajendiran, Thekkelnaycke, Vo, Josh N, Delekta, Andrew D, Wang, Lisha, Xiao, Lanbo, Hodge, Nathan B, Desai, Parth, Mendoza, Sergio, Juckette, Kristin, Xu, Alice, Soni, Tanu, Su, Fengyun, Wang, Rui, Cao, Xuhong, Yu, Jiali, Kryczek, Ilona, Wang, Xiao-Ming, Wang, Xiaoju, Siddiqui, Javed, Wang, Zhen, Bernard, Amélie, Fernandez-Salas, Ester, Navone, Nora M, Ellison, Stephanie J, Ding, Ke, Eskelinen, Eeva-Liisa, Heath, Elisabeth I, Klionsky, Daniel J, Zou, Weiping, Chinnaiyan, Arul M

“…Multi-tyrosine kinase inhibitors (MTKIs) have thus far had limited success in the treatment of castration-resistant prostate cancer (CRPC). Here, we report a…”
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Maximum growth and survival of estrogen receptor-alpha positive breast cancer cells requires the Sin3A transcriptional repressor by Ellison-Zelski, Stephanie J, Alarid, Elaine T

“…Sin3A is an evolutionarily conserved transcriptional repressor which regulates gene expression as part of the multi-protein Sin3 repressive complex. It…”
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Inhibiting androgen receptor nuclear entry in castration-resistant prostate cancer by Pollock, Julie A, Wardell, Suzanne E, Parent, Alexander A, Stagg, David B, Ellison, Stephanie J, Alley, Holly M, Chao, Christina A, Lawrence, Scott A, Stice, James P, Spasojevic, Ivan, Baker, Jennifer G, Kim, Sung Hoon, McDonnell, Donald P, Katzenellenbogen, John A, Norris, John D

“…A cyclobutane compound competitively inhibits the activity of androgen receptors (AR) containing antiandrogen-resistant mutations through stabilization of the…”
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Antisense oligonucleotides to therapeutically target SARS-CoV-2 infection by Yuanyuan Qiao, Jesse W Wotring, Charles J Zhang, Xia Jiang, Lanbo Xiao, Andy Watt, Danielle Gattis, Eli Scandalis, Susan Freier, Yang Zheng, Carla D Pretto, Stephanie J Ellison, Eric E Swayze, Shuling Guo, Jonathan Z Sexton, Arul M Chinnaiyan

“…Although the COVID-19 pandemic began over three years ago, the virus responsible for the disease, SARS-CoV-2, continues to infect people across the globe. As…”
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Pin1 modulates ERα levels in breast cancer through inhibition of phosphorylation-dependent ubiquitination and degradation by Rajbhandari, P, Schalper, K A, Solodin, N M, Ellison-Zelski, S J, Ping Lu, K, Rimm, D L, Alarid, E T

“…Estrogen receptor-alpha (ERα) is an important biomarker used to classify and direct therapy decisions in breast cancer (BC). Both ERα protein and its…”
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Proteasome inhibition represses ERα gene expression in ER+ cells: a new link between proteasome activity and estrogen signaling in breast cancer by Powers, G L, Ellison-Zelski, S J, Casa, A J, Lee, A V, Alarid, E T

“…Estrogen receptor-α (ERα) is a major therapeutic target of hormonal therapies in breast cancer, and its expression in tumors is predictive of clinical…”
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Molecular determinants of gene repression in estrogen signaling in breast cancer by Ellison-Zelski, Stephanie J

“…The estrogen signaling pathway has been clearly linked to breast cancer growth and development for several decades. Because of this, estrogen receptor-alpha…”
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